Kaviya Devaraja
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QLTI-14. Enhancing Awareness and Use of Support Services for Adolescents and Young Adults with High-Grade Glioma: Evaluating 1-Minute Videos and Centralized Resource Navigator Open
BACKGROUND Adolescents and young adults (AYAs) diagnosed with high-grade glioma (HGG) experience profound disruptions in education, employment, relationships, and identity during a pivotal stage of life. Previous work has revealed substant…
Sexual Health of Adolescent and Young Adults Assigned Female at Birth Post Pelvic Radiotherapy Open
Purpose Pelvic radiotherapy (PRT) is an effective cancer treatment for pelvic malignancies but often results in sexual dysfunction and long-term complications, particularly for patients with a vagina. This impact is heightened in adolescen…
View article: Navigating Life With High‐Grade Glioma: Experiences and Needs of Adolescents and Young Adults
Navigating Life With High‐Grade Glioma: Experiences and Needs of Adolescents and Young Adults Open
Background Adolescents and young adults (AYA, 18–39) with high‐grade glioma (HGG) face unique challenges at a life stage focused on autonomy, careers, relationships, and family planning. Aim This study explores their experiences to inform …
TMIC-80. HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC TUMOR MICROENVIRONMENT IN GLIOBLASTOMA Open
Gliobastoma (GBM) is a highly aggressive solid tumor of the brain, characterized by a hypoxic tumor microevironment (TME) leading to histopathological features of necrosis, microvascular proliferation and deregulated hypervascularization. …
TMIC-75. ICAM-1 PROMOTES AN IMMUNOSUPPRESSIVE LANDSCAPE IN GLIOBLASTOMAS BY REGULATING THE PHENOTYPIC POLARIZATION STATE OF TUMOR ASSOCIATED MACROPHAGES Open
Glioblastoma (GBM) is a fatal adult CNS tumor, with a median overall survival of 12-15 months. Intercellular adhesion molecule 1 (ICAM-1) is a cell adhesion molecule whose expression is significantly greater in the mesenchymal transcriptio…
View article: Insights from GoFundMe posts: Analyzing GoFundMe financial aid requests from brain tumor patients in Ontario, Canada
Insights from GoFundMe posts: Analyzing GoFundMe financial aid requests from brain tumor patients in Ontario, Canada Open
Background Primary central nervous system (CNS) tumors significantly affect individuals globally, with patients in Ontario, Canada, often bearing financial burdens for treatments such as oral chemotherapy due to insufficient coverage, resu…
Adapting an Adolescent and Young Adult Program Housed in a Quaternary Cancer Centre to a Regional Cancer Centre: Creating Equitable Access to Developmentally Tailored Support Open
Adolescents and young adults (AYAs) with cancer, representing those between 15 and 39 years of age, face distinctive challenges balancing their life stage with the physical, emotional, and social impacts of a cancer diagnosis. These challe…
TMIC-17. THE ROLE OF ICAM1 IN GLIOBLASTOMA TUMORIGENESIS UNDER HYPOXIC CONDITIONS Open
Glioblastoma (GBM) is a deadly brain cancer in adults with limited treatment options. Cell adhesion molecules (CAMs) mediate cell-cell interactions and migration. Intercellular adhesion molecule 1 (ICAM-1) is a CAM expressed by various cel…
View article: DISP-05. UNDERSTANDING THE INDIVIDUAL CHALLENGES AND EXPERIENCES OF YOUNG ADULTS WITH A DIAGNOSIS OF GLIOBLASTOMA AND HIGH-GRADE ASTROCYTOMA
DISP-05. UNDERSTANDING THE INDIVIDUAL CHALLENGES AND EXPERIENCES OF YOUNG ADULTS WITH A DIAGNOSIS OF GLIOBLASTOMA AND HIGH-GRADE ASTROCYTOMA Open
High-grade gliomas are highly aggressive and fatal primary malignant brain tumors in adults with ineffective existing treatment methods. Older adults are greatly impacted by high-grade gliomas as they are more common among this population.…
TMIC-31. MULTI-PLATFORM GENOMIC LANDSCAPE OF INTRA-TUMORAL HYPOXIA IN GLIOBLASTOMA Open
Hypoxia is a prominent characteristic of aggressive tumors, including glioblastoma (GB), and is linked to therapy resistance. Understanding the molecular mechanisms underlying hypoxia-induced changes in neoplastic and non-neoplastic cells …
TMIC-82. SPATIAL AND SINGLE-CELL PROTEOMIC LANDSCAPING OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA Open
Glioblastoma (GBM) is a fatal adult solid tumour with median overall survival of 18-20 months post-diagnosis; contributing factors to therapeutic inefficacy include acquisition of genomic alterations post-therapy, immune evasion, deregulat…
View article: QOL-24. FINANCIAL AID REQUESTS BY BRAIN TUMOR PATIENTS IN ONTARIO THROUGH GOFUNDME
QOL-24. FINANCIAL AID REQUESTS BY BRAIN TUMOR PATIENTS IN ONTARIO THROUGH GOFUNDME Open
Brain tumors affect individuals globally including Ontario residents. Numerous Ontario brain tumor patients suffer the unequal burden of responsibility to pay for treatments like oral chemotherapy. In addition to chemotherapy, patients and…
View article: SPCR-06 FINANCIAL AID REQUESTS BY BRAIN TUMOR PATIENTS IN ONTARIO THROUGH GOFUNDM
SPCR-06 FINANCIAL AID REQUESTS BY BRAIN TUMOR PATIENTS IN ONTARIO THROUGH GOFUNDM Open
OBJECTIVE/PURPOSE Ontario brain tumor patients sometimes suffer the burden of responsibility to pay for treatments like oral chemotherapy. However, less is known about other direct and indirect financial costs due to their diagnosis. The p…
BSBM-07 HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA Open
Rapidly growing solid tumors such as glioblastoma (GBM) are characteristically hypoxic, displaying large areas of necrosis surrounded by hyperproliferative pseudopalisading cells. Intra-tumoral hypoxia develops over time in the three-dimen…
THE ROLE OF ICAM1 IN TUMOR ASSOCIATED MACROPHAGES IN GLIOBLASTOMA TUMORIGENESIS Open
Glioblastoma (GBM) is a fatal brain cancer in adults with ineffective treatment methods. Cell adhesion molecules (CAMs) are proteins that are expressed on the surface of cells and enable them to interact with one another and the surroundin…
HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA Open
Rapidly growing solid tumors such as glioblastoma (GBM) are characteristically hypoxic, displaying large areas of necrosis surrounded by hyperproliferative pseudopalisading cells. Intra-tumoral hypoxia develops over time in the three-dimen…
TMIC-60. THE ROLE OF ICAM1 IN GLIOBLASTOMA TUMORIGENESIS UNDER HYPOXIC CONDITIONS Open
Glioblastoma (GBM) is a fatal brain cancer in adults with ineffective existing treatment methods. Cell adhesion molecules (CAMs) are proteins that are expressed on the surface of cells and enable them to interact with one another and the s…
TMIC-73. HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA Open
Rapidly growing solid tumors such as glioblastoma (GBM) are characteristically hypoxic, displaying large areas of necrosis surrounded by hyperproliferative pseudopalisading cells. Intra-tumoral hypoxia develops over time in the three-dimen…
BSCI-14 THE ROLE OF ICAM1 IN GLIOBLASTOMA TUMOUR ASSOCIATED MACROPHAGES UNDER HYPOXIC CONDITIONS Open
BACKGROUND Glioblastoma (GBM) is an aggressive and highly fatal brain cancer in adults. Existing treatment methods are ineffective and we are in need of new treatments that extend the overall survival and improve quality-of-life. Cell adhe…