Kayleigh Griffiths
YOU?
Author Swipe
View article: ALDH2 polymorphism and myocardial infarction: From alcohol metabolism to redox regulation
ALDH2 polymorphism and myocardial infarction: From alcohol metabolism to redox regulation Open
Acute myocardial infarction (AMI) remains a leading cause of death worldwide. Increased formation of reactive oxygen species (ROS) during the early reperfusion phase is thought to trigger lipid peroxidation and disrupt redox homeostasis, l…
View article: Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling Open
Aims Under hypoxic conditions, nitrite (NO2−) can be reduced to nitric oxide (NO) eliciting vasorelaxation. However, nitrite also exerts vasorelaxant effects of potential therapeutic relevance under normal physiological conditions via unde…
View article: Serum amyloid A levels are associated with polymorphic variants in the serum amyloid A 1 and 2 genes
Serum amyloid A levels are associated with polymorphic variants in the serum amyloid A 1 and 2 genes Open
We have identified novel genetic variants in the SAA genes associated with SAA levels, a biomarker of inflammation and chronic disease. The utility of SAA as a biomarker for inflammation and chronic disease may be influenced by underlying …
View article: Type 2 Diabetes in Young Females Results in Increased Serum Amyloid A and Changes to Features of High Density Lipoproteins in Both HDL<sub>2</sub>and HDL<sub>3</sub>
Type 2 Diabetes in Young Females Results in Increased Serum Amyloid A and Changes to Features of High Density Lipoproteins in Both HDL<sub>2</sub>and HDL<sub>3</sub> Open
Persons with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerosis. High-density lipoproteins (HDL) normally protect against cardiovascular disease (CVD), but this may be attenuated by serum amyloid A (SAA). In a case-co…