Kazeem Adeleke
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View article: Predictors of cervical precancerous lesions among women attending an urban Primary Health Centre in Lagos State, Nigeria
Predictors of cervical precancerous lesions among women attending an urban Primary Health Centre in Lagos State, Nigeria Open
Background: Cervical cancer remains a major public health issue in Nigeria, significantly contributing to women’s morbidity and mortality. This study aimed to identify predictors of cervical precancerous lesions among Nigerian women attend…
View article: Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency - Real World Evidence
Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency - Real World Evidence Open
Background: Growth hormone replacement is indicated in adults with severe growth hormone (GH) deficiency, adult growth hormone deficiency assessment (AGHDA) score of at least 11 and are receiving treatment for other pituitary hormone defic…
View article: 8407 Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency: Real World Evidence
8407 Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency: Real World Evidence Open
Disclosure: E. Ssemmondo: None. N. Nadarajah: None. S. Brooks: None. R. Akinyombo JNR: None. K.A. Adeleke: None. H. Deshmukh: None. T. Sathyapalan: None. Introduction: Growth hormone replacement is indicated in adults with severe growth ho…
View article: Exploring shared frailty models for cluster-specific risk estimation: A study on diabetes patients with a history of acute coronary syndrome
Exploring shared frailty models for cluster-specific risk estimation: A study on diabetes patients with a history of acute coronary syndrome Open
This study proposes the use of semiparametric log-normal shared frailty models to analyze time-to-event data for individuals with similar features referred to as clusters. Shared frailty models are useful for modeling and estimating common…
View article: Time to first remission and survival in patients with acromegaly: Evidence from the UK Acromegaly Register Study (UKAR)
Time to first remission and survival in patients with acromegaly: Evidence from the UK Acromegaly Register Study (UKAR) Open
Objective This study aimed to understand the effect of time to remission of acromegaly on survival in people living with acromegaly. Design, Patients and Measurement This cross‐sectional study used data from the UK Acromegaly Register. We …
View article: Effect of intermittently scanned continuous glucose monitoring in people with diabetes with a psychosocial indication for initiation
Effect of intermittently scanned continuous glucose monitoring in people with diabetes with a psychosocial indication for initiation Open
Aim To understand the effect of intermittently scanned continuous glucose monitoring (isCGM) in people with diabetes with a ‘psychosocial’ indication for access. Methods The study utilized baseline and follow‐up data from the Association o…
View article: Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study
Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study Open
Aims To evaluate the clinical features and impact of flash glucose monitoring in older adults with type 1 diabetes (T1D) across age groups defined as young‐old, middle‐old, and old‐old. Materials and Methods Clinicians were invited to subm…
View article: THU060 Time To First Remission, Medical Therapy And Survival In Acromegaly: UK Acromegaly Register (UKAR) Study
THU060 Time To First Remission, Medical Therapy And Survival In Acromegaly: UK Acromegaly Register (UKAR) Study Open
Disclosure: H. Deshmukh: None. E. Ssemmondo: None. K. Adeleke: None. L. Batten: None. M. Aye: None. T. Sathyapalan: None. Introduction: There are limited data on the effect of time to remission of acromegaly and survival in people living w…
View article: Assessing the androgenic and metabolic heterogeneity in polycystic ovary syndrome using cluster analysis
Assessing the androgenic and metabolic heterogeneity in polycystic ovary syndrome using cluster analysis Open
Introduction Some but not all women with polycystic ovary syndrome (PCOS) develop the metabolic syndrome (MS). The objective of this study was to determine if a subset of women with PCOS had higher androgen levels predisposing them to MS a…
View article: Generalized Beta-Exponential Weibull Distribution and its Applications
Generalized Beta-Exponential Weibull Distribution and its Applications Open
In this article, we investigate a distribution called the generalized beta-exponential Weibull distribution. Beta exponential x family of link function which is generated from family of generalized distributions is used in generating the n…
View article: Gamma and Inverse Gaussian Frailty Models with Time-varying co-variates Based on Some Parametric Baseline Hazards Functions
Gamma and Inverse Gaussian Frailty Models with Time-varying co-variates Based on Some Parametric Baseline Hazards Functions Open
Ignoring the existence of frailty term in the analysis of survival time data, when heterogeneity is present will produce a less accurate estimated parameters with higher standard errors. In survival analysis, Cox proportional hazards model…
View article: An Alternative Stratified Cox Model for Correlated Variables in Infant Mortality
An Alternative Stratified Cox Model for Correlated Variables in Infant Mortality Open
Often in epidemiological research, introducing a stratified Cox model can account for the existence of interactions of some inherent factors with some major/noticeable factors. This paper aims at modelling correlated variables in infant mo…
View article: Analysis of Diabetes Data using Extended Cox Model with Frailty under Partial and Penalized partial likelihood estimation methods
Analysis of Diabetes Data using Extended Cox Model with Frailty under Partial and Penalized partial likelihood estimation methods Open
Data on Diabetes were analyzed using partial likelihood (Pl) and penalized partial likelihood (Ppl) estimation methods in non-proportional hazards model with dichotomous time-varying covariates. Gamma and Inverse Gaussian frailty distribut…
View article: An Empirical Comparison between Partial Likelihood and Penalized Partial Likelihood Estimators for Semi-parametric Non-proportional Hazards Models with Frailty
An Empirical Comparison between Partial Likelihood and Penalized Partial Likelihood Estimators for Semi-parametric Non-proportional Hazards Models with Frailty Open
This study compared partial likelihood (PL) and penalized partial likelihood (PPL) estimators in non-proportional hazards model with dichotomous time-varying covariates and subject–specific frailty. We considered Gamma and Inverse Gaussian…
View article: Extended Cox Modelling of Survival Data with Guarantee Time
Extended Cox Modelling of Survival Data with Guarantee Time Open
Proportional Hazard regression model for censored survival data often specifies that covariates have a proportional fixed effect on the hazard function of the lifetime distribution of a subject. A modification of the proportional hazards m…
View article: Time-varying covariates and coefficients in Cox regression models
Time-varying covariates and coefficients in Cox regression models Open
Time-varying covariance occurs when a covariate changes over time during the follow-up period. Such variable can be analyzed with the Cox regression model to estimate its effect on survival time. For this it is essential to organize the da…
View article: Time-varying covariates and coefficients in Cox regression models
Time-varying covariates and coefficients in Cox regression models Open
Time-varying covariance occurs when a covariate changes over time during the follow-up period. Such variable can be analyzed with the Cox regression model to estimate its effect on survival time. For this it is essential to organize the da…