Kazue Uchida
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View article: Oncostatin M enhances the lengthening of sensory nerves and skin hypersensitivity
Oncostatin M enhances the lengthening of sensory nerves and skin hypersensitivity Open
Background Oncostatin M (OSM) is a cytokine that mediates inflammatory processes and is overexpressed in skin lesions of atopic dermatitis (AD). By amplifying neural responses to chemicals such as histamine, OSM increases sensitivity to pr…
View article: Intradermal injection of human sweat enhances production of specific IgG against antigens solved in the sweat
Intradermal injection of human sweat enhances production of specific IgG against antigens solved in the sweat Open
View article: Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching
Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching Open
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intermittent itchy rash. Type 2 inflammatory cytokines such as interleukin (IL)-4, IL-13, and IL-31 are strongly implicated in AD pathogenesis. Stimu…
View article: Time Course of Priming Effect of TF Inducers on Synergistic TF Expression and Intra-Cellular Gap Formation of Human Vascular Endothelial Cells via the Extrinsic Coagulation Cascade
Time Course of Priming Effect of TF Inducers on Synergistic TF Expression and Intra-Cellular Gap Formation of Human Vascular Endothelial Cells via the Extrinsic Coagulation Cascade Open
Chronic spontaneous urticaria (CSU) is characterized by daily recurring wheal and flare with itch for more than 6 weeks. The extrinsic coagulation system has been shown to be activated in correlation with CSU severity. We have reported tha…
View article: Identification of protein kinase C domains involved in its translocation induced by propofol
Identification of protein kinase C domains involved in its translocation induced by propofol Open
View article: Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic
Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic Open
Many anesthetics, including Propofol, have been reported to induce elevation of intracellular calcium, and we were interested to investigate the possible contribution of calcium elevation to the mechanism of the newly approved remimazolam …
View article: Effects of LPS and TNFα on the histamine responsiveness of vascular endothelial cells
Effects of LPS and TNFα on the histamine responsiveness of vascular endothelial cells Open
Patients with chronic spontaneous urticarial (CSU) are often resistant to treatment with H1 antihistamines and have an increased response to intradermal injection of histamine. In this study, we evaluated the changes of responsiveness of v…
View article: The Influence of a Legal Revision on Infectious Agent Surveillance in Local Public Health Institutes
The Influence of a Legal Revision on Infectious Agent Surveillance in Local Public Health Institutes Open
目的：感染症の予防及び感染症の患者に対する医療に関する法律（感染症法）の改正により，2016 年4 月から病原体サーベイランスの情報収集体制が強化された．そこで，5 類定点把握対象のウイルス性疾患について，その影響を検討した．
View article: Synergistic expression of tissue factors on vascular endothelial cells induce intercellular gap formation in the presence of plasma via extrinsic coagulation cascade and PAR-1
Synergistic expression of tissue factors on vascular endothelial cells induce intercellular gap formation in the presence of plasma via extrinsic coagulation cascade and PAR-1 Open
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