Kazuhito Oba
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View article: Area of center of pressure in closed eye setting as a measure of postural sway: Association with frailty and functional capacity in older adults with diabetes
Area of center of pressure in closed eye setting as a measure of postural sway: Association with frailty and functional capacity in older adults with diabetes Open
Older adults with diabetes mellitus are at a higher risk of frailty, which can lead to disability and death; therefore, effective frailty screening is necessary in such populations. However, evidence linking sway meter indices to frailty o…
View article: High red blood cell distribution width associated with incident frailty in patients with cardiometabolic diseases: A longitudinal study
High red blood cell distribution width associated with incident frailty in patients with cardiometabolic diseases: A longitudinal study Open
Frailty is an important health issue in older adults that leads to disability and increased mortality. Red blood cell distribution width (RDW), a measure of variability in red blood cell volume, is associated with inflammation, anemia, and…
View article: Reply to the comments of Saleh <i>et al</i>. on “Coexistence of high visceral fat area and sarcopenia and atherosclerotic markers in old‐old patients with diabetes: Is there an association?”
Reply to the comments of Saleh <i>et al</i>. on “Coexistence of high visceral fat area and sarcopenia and atherosclerotic markers in old‐old patients with diabetes: Is there an association?” Open
View article: Coexistence of high visceral fat area and sarcopenia is associated with atherosclerotic markers in old‐old patients with diabetes: A cross‐sectional study
Coexistence of high visceral fat area and sarcopenia is associated with atherosclerotic markers in old‐old patients with diabetes: A cross‐sectional study Open
Aims/Introduction To investigate whether sarcopenic obesity is associated with the progression of atherosclerotic lesions in older patients with diabetes and to identify the obesity components of sarcopenic obesity that best reflect athero…
View article: Changes in Physical Activity Before, During, and After the State of Emergency due to Covid-19 Pandemic and its Association with Incidence of Frailty in Older Outpatients with Cardiometabolic Disease
Changes in Physical Activity Before, During, and After the State of Emergency due to Covid-19 Pandemic and its Association with Incidence of Frailty in Older Outpatients with Cardiometabolic Disease Open
View article: Adrenal Insufficiency and Thyrotoxicosis Following Combined Immune Checkpoint Inhibitor Use: A Case Report and Literature Review
Adrenal Insufficiency and Thyrotoxicosis Following Combined Immune Checkpoint Inhibitor Use: A Case Report and Literature Review Open
Destructive thyroiditis and secondary adrenal insufficiency are major endocrinological immune-related adverse events of immune checkpoint inhibitors (ICIs). However, the timing at which each event occurs most frequently after drug administ…
View article: Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report
Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report Open
Background Although vaccination against coronavirus disease (COVID-19) has several side effects, hypopituitarism due to hypophysitis has rarely been reported. Case presentation An 83-year-old healthy woman, who had received her fourth COVI…
View article: Investigating the quality of TMT-B errors in MOCA-J.
Investigating the quality of TMT-B errors in MOCA-J. Open
View article: The cross-sectional area of erector spinae muscle and the liver-to-spleen ratio are associated with frailty in older patients with diabetes: a cross-sectional study
The cross-sectional area of erector spinae muscle and the liver-to-spleen ratio are associated with frailty in older patients with diabetes: a cross-sectional study Open
View article: Erector spinae muscle area and the ratio of the computed tomography values of the liver and spleen are associated with frailty in older patients with diabetes: A cross-sectional study
Erector spinae muscle area and the ratio of the computed tomography values of the liver and spleen are associated with frailty in older patients with diabetes: A cross-sectional study Open
Background Older patients with diabetes mellitus are more susceptible to frailty. Although some imaging markers of appendicular skeletal muscle mass obtained using dual-energy X-ray absorptiometry or computed tomography (CT) imaging can re…
View article: Association between white matter alterations on diffusion tensor imaging and incidence of frailty in older adults with cardiometabolic diseases
Association between white matter alterations on diffusion tensor imaging and incidence of frailty in older adults with cardiometabolic diseases Open
Diffusion tensor imaging (DTI) can be used for the early detection of abnormal changes in the integrity of cerebral white matter tracts, and we have previously reported that these changes are associated with indices of early atheroscleroti…
View article: ANGT_HUMAN[448–462], an Anorexigenic Peptide Identified Using Plasma Peptidomics
ANGT_HUMAN[448–462], an Anorexigenic Peptide Identified Using Plasma Peptidomics Open
The discovery of bioactive peptides is an important research target that enables the elucidation of the pathophysiology of human diseases and provides seeds for drug discovery. Using a large number of native peptides previously identified …
View article: A geriatric case of hyperosmolar hyperglycemic state with osmotic demyelination syndrome that manifested with dysphagia
A geriatric case of hyperosmolar hyperglycemic state with osmotic demyelination syndrome that manifested with dysphagia Open
The patient was an 84-year-old man who had been on insulin therapy for type 2 diabetes mellitus for 55 years. He had undergone bile duct stenting to avoid obstruction due to adenocarcinoma of the bile duct. The patient had suffered from fe…
View article: Dynapenic abdominal obesity is associated with mild cognitive impairment in patients with cardiometabolic disease: a cross-sectional study
Dynapenic abdominal obesity is associated with mild cognitive impairment in patients with cardiometabolic disease: a cross-sectional study Open
View article: Subclinical Atherosclerosis, Vascular Risk Factors, and White Matter Alterations in Diffusion Tensor Imaging Findings of Older Adults With Cardiometabolic Diseases
Subclinical Atherosclerosis, Vascular Risk Factors, and White Matter Alterations in Diffusion Tensor Imaging Findings of Older Adults With Cardiometabolic Diseases Open
White matter abnormalities may reflect cerebral microvessel disease. Diffusion tensor imaging (DTI) can help detect early changes in white matter integrity in each tract. However, studies investigating the relationship between subclinical …
View article: A case of hyperammonemia caused by urinary tract infection due to urease-producing bacteria in dementia with Lewy bodies
A case of hyperammonemia caused by urinary tract infection due to urease-producing bacteria in dementia with Lewy bodies Open
An 87-year-old woman diagnosed with dementia with Lewy bodies (DLB) 2 years earlier was referred to our institution because of difficulty walking. She was diagnosed with urinary tract infection and admitted to our hospital. During hospital…
View article: Suprabasin-derived bioactive peptides identified by plasma peptidomics
Suprabasin-derived bioactive peptides identified by plasma peptidomics Open
View article: Associations between sarcopenia and white matter alterations in older adults with diabetes mellitus: A diffusion tensor imaging study
Associations between sarcopenia and white matter alterations in older adults with diabetes mellitus: A diffusion tensor imaging study Open
Aims/Introduction Older adults with diabetes mellitus are susceptible to sarcopenia. Diffusion tensor imaging studies have also shown that patients with diabetes have altered white matter integrity. However, the relationship between these …
View article: Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma
Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma Open
A 47‐year‐old woman with a history of diabetes mellitus (DM) and obesity was admitted to our hospital for glucose control. She was detected to have hypertension (HT) and diagnosed with primary aldosteronism (PA) based on the high level of …
View article: Table of Contents
Table of Contents Open
View article: Thromboxane A<sub>2</sub>induces blood flow recovery via platelet adhesion to ischaemic regions
Thromboxane A<sub>2</sub>induces blood flow recovery via platelet adhesion to ischaemic regions Open
These results indicated that TP signalling facilitates ischaemia-induced angiogenesis via P-selectin-mediated platelet adhesion to PSGL-1 on the ECs at ischaemic sites and the supply of pro-angiogenic factors by the adherent platelets.