Kazuki Sakatoku
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View article: Improved Transplant Outcomes With Alternative Donors in Myelofibrosis: A 20‐Year Japanese Registry Analysis of Donor Sources and the Impact of Ruxolitinib
Improved Transplant Outcomes With Alternative Donors in Myelofibrosis: A 20‐Year Japanese Registry Analysis of Donor Sources and the Impact of Ruxolitinib Open
This study of 308 myelofibrosis patients shows that in recent years (2013-2019), alternative donors (mismatched unrelated donors and cord blood) achieved survival rates comparable to HLA-matched donors-a significant improvement compared to…
View article: Mogamulizumab Concentration-guided Allogeneic Transplantation and Successful Intrathecal Chemotherapy for Central Nervous System-relapsed Adult T-cell Leukemia/Lymphoma
Mogamulizumab Concentration-guided Allogeneic Transplantation and Successful Intrathecal Chemotherapy for Central Nervous System-relapsed Adult T-cell Leukemia/Lymphoma Open
Adult T-cell leukemia/lymphoma (ATL) has a poor prognosis, with mogamulizumab effectively controlling the disease but increasing graft-versus-host disease (GVHD) risk during transplantation if residual levels persist. We herein report a 61…
View article: T cells with high BCL-2 expression induced by venetoclax impact anti-leukemic immunity “graft-versus-leukemia effects”
T cells with high BCL-2 expression induced by venetoclax impact anti-leukemic immunity “graft-versus-leukemia effects” Open
View article: B-054 Potential of Autotaxin in the Early Diagnosis of Sinusoidal Obstruction Syndrome after Allogeneic Hematopoietic Cell Transplantation
B-054 Potential of Autotaxin in the Early Diagnosis of Sinusoidal Obstruction Syndrome after Allogeneic Hematopoietic Cell Transplantation Open
Background Sinusoidal obstruction syndrome (SOS) is a life-threatening complication after allogeneic hematopoietic cell transplantation (allo-HCT). Early intervention leads to a good prognosis, but it is often difficult to differentiate SO…
View article: Immunomodulatory and direct activities of ropeginterferon alfa‐2b on cancer cells in mouse models of leukemia
Immunomodulatory and direct activities of ropeginterferon alfa‐2b on cancer cells in mouse models of leukemia Open
Although ropeginterferon alfa‐2b has recently been clinically applied to myeloproliferative neoplasms with promising results, its antitumor mechanism has not been thoroughly investigated. Using a leukemia model developed in immunocompetent…
View article: Prognostic Impact of the Subcutaneous Adipose Tissue Loss on Survival Outcome in Patients with Multiple Myeloma
Prognostic Impact of the Subcutaneous Adipose Tissue Loss on Survival Outcome in Patients with Multiple Myeloma Open
Increasing evidence indicates that reduced mass of skeletal muscle or adipose tissue can predict negative outcomes in patients with solid tumors. But its significance and prognostic impact on outcomes in patients with multiple myeloma (MM)…
View article: Nodular Cytomegalovirus Pneumonia
Nodular Cytomegalovirus Pneumonia Open
A 68-year-old man presented with widespread lymphadenopathy.A lymph node biopsy showed peripheral T-cell lymphoma.Multiple nodules were detected in both lungs on CT.A transbronchial lung biopsy revealed cytomegalic inclusion bodies in the …