Kazuo Kondo
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View article: Egg Consumption and Coronary Artery Disease in Japanese Patients Undergoing Coronary Angiography
Egg Consumption and Coronary Artery Disease in Japanese Patients Undergoing Coronary Angiography Open
Many prospective studies of egg consumption and coronary artery disease (CAD) provided conflicting findings, and ethnicity may influence CAD risk. Two Japanese cohort studies, which were conducted around 1990, reported no significant assoc…
View article: The Inverse Association between Alcohol Consumption and Coronary Artery Disease in Japanese Men Undergoing Coronary Angiography
The Inverse Association between Alcohol Consumption and Coronary Artery Disease in Japanese Men Undergoing Coronary Angiography Open
Several Japanese cohort studies reported that alcohol consumption was inversely associated with coronary artery disease (CAD). However, these results were inconsistent. We investigated alcohol consumption and CAD in 802 patients undergoing…
View article: Supply Chain Market Linkage Strategies for Small Holder Tomato Producers in Zimbabwe
Supply Chain Market Linkage Strategies for Small Holder Tomato Producers in Zimbabwe Open
There is a lack of coordinated market linkages to assist the smallholder farmer, especially tomato producers in Zimbabwe. The study's goal was to establish supply chain market linkage strategies for small-holder tomato producers in Zimbabw…
View article: Glucose and Insulin Differently Regulate Gluconeogenic and Ureagenic Gene Expression
Glucose and Insulin Differently Regulate Gluconeogenic and Ureagenic Gene Expression Open
Glucose and insulin positively regulate glycolysis and lipogenesis through the activation of carbohydrate response element-binding protein (ChREBP) and sterol regulatory element-binding protein 1c (SREBP1c), but their respective roles in t…
View article: Associations between the Intakes of Plant Foods and Coronary Artery Disease in Japanese Patients Undergoing Coronary Angiography
Associations between the Intakes of Plant Foods and Coronary Artery Disease in Japanese Patients Undergoing Coronary Angiography Open
Several Japanese cohort studies have reported that the intakes of plant foods, such as vegetables, fruits, seaweed, and soy products, are inversely associated with coronary artery disease (CAD). However, the results of these studies have b…
View article: High Plasma Levels of Sestrin2 Are Associated with Cardiovascular Events in Patients Undergoing Coronary Angiography
High Plasma Levels of Sestrin2 Are Associated with Cardiovascular Events in Patients Undergoing Coronary Angiography Open
Atherosclerotic diseases, like coronary artery disease (CAD), are recognized to be associated with oxidative stress and inflammation. Sestrin2 is a stress-inducible protein that has anti-oxidant and anti-inflammatory properties. We previou…
View article: Age-Related Effects of Olive Oil Polyphenol Ingestion on Oxidation of Low-Density Lipoprotein in Healthy Japanese Men: A Randomized Controlled Double-Blind Crossover Trial
Age-Related Effects of Olive Oil Polyphenol Ingestion on Oxidation of Low-Density Lipoprotein in Healthy Japanese Men: A Randomized Controlled Double-Blind Crossover Trial Open
Background: The function of olive oil polyphenols in suppressing the oxidation of low-density lipoprotein (LDL) is well-known in Europeans. However, it remains unclear whether olive oil polyphenols exert antioxidant effects in Japanese peo…
View article: Association between Plasma Interleukin-27 Levels and Cardiovascular Events in Patients Undergoing Coronary Angiography
Association between Plasma Interleukin-27 Levels and Cardiovascular Events in Patients Undergoing Coronary Angiography Open
Atherosclerotic disease, including coronary heart disease (CHD), is one of the chronic inflammatory conditions, and an imbalance between pro-inflammatory and anti-inflammatory cytokines plays a role in the process of atherosclerosis. Inter…
View article: Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography
Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography Open
TGF-β is recognized as playing a protective role against atherosclerosis. Endoglin is a receptor for TGF-β, and its expression is upregulated in atherosclerotic plaques. Endoglin is secreted from the cell membrane into the circulation as a…
View article: EP07.01-31 Preoperative Respiratory Assessment Predicts Post-Operative Survival in Stage IA Non-small Cell Lung Cancer
EP07.01-31 Preoperative Respiratory Assessment Predicts Post-Operative Survival in Stage IA Non-small Cell Lung Cancer Open
View article: Association between the Japanese Diet and Coronary Artery Disease in Patients Undergoing Coronary Angiography
Association between the Japanese Diet and Coronary Artery Disease in Patients Undergoing Coronary Angiography Open
Several cohort studies have reported that the Japanese diet is associated with reduced cardiovascular disease mortality. However, the results were not always consistent, and most of those studies conducted dietary surveys around 1990. We i…
View article: Effects of acute strawberry consumption on serum levels of vitamin C and folic acid, the antioxidant potential of LDL and blood glucose response: a randomised cross-over controlled trial
Effects of acute strawberry consumption on serum levels of vitamin C and folic acid, the antioxidant potential of LDL and blood glucose response: a randomised cross-over controlled trial Open
Strawberry contains many bioactive compounds such as vitamin C and polyphenols as well as folate, a vitamin that is especially important for women of childbearing age. We investigated the effects of the acute consumption of strawberry on t…
View article: Plasma Concentrations of Vinculin versus Talin-1 in Coronary Artery Disease
Plasma Concentrations of Vinculin versus Talin-1 in Coronary Artery Disease Open
Vinculin and talin-1, which are cytoskeletal proteins affecting focal adhesions, were reported to be down-expressed in atherosclerotic lesions. Recently, we reported high concentrations of plasma talin-1 in patients with coronary artery di…
View article: High Plasma Levels of Fortilin in Patients with Coronary Artery Disease
High Plasma Levels of Fortilin in Patients with Coronary Artery Disease Open
Excessive apoptosis is known to be a common feature of atherosclerotic lesions. Fortilin is recognized to have potent antiapoptotic properties. An increased fortilin expression was demonstrated in atherosclerotic lesions, and fortilin knoc…
View article: No Significant Association Between Plasma Endosialin Levels and the Presence or Severity of Coronary Artery Disease
No Significant Association Between Plasma Endosialin Levels and the Presence or Severity of Coronary Artery Disease Open
Plasma endosialin levels in patients with CAD were found to be not higher than in those without CAD and to be not significantly associated with the presence or severity of CAD.
View article: Association between Plasma Follistatin-like Protein 1 Levels and the Presence and Severity of Coronary Artery Disease
Association between Plasma Follistatin-like Protein 1 Levels and the Presence and Severity of Coronary Artery Disease Open
Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein known for its role in inflammation. However, plasma FSTL1 levels in patients with coronary artery disease (CAD) have not been fully elucidated. Thus, in this study, we investiga…
View article: The Protective Role of Sestrin2 in Atherosclerotic and Cardiac Diseases
The Protective Role of Sestrin2 in Atherosclerotic and Cardiac Diseases Open
Atherosclerotic disease, such as coronary artery disease (CAD), is known to be a chronic inflammatory disease, as well as an age-related disease. Excessive oxidative stress produced by reactive oxygen species (ROS) contributes to the patho…
View article: Validation of Food-Frequency Questionnaires for Polyphenol Intake in Japanese Adults
Validation of Food-Frequency Questionnaires for Polyphenol Intake in Japanese Adults Open
Estimations of individuals' polyphenol intake contributes to the understanding of the health benefits of dietary polyphenol. We developed a food frequency questionnaire for polyphenol intake (FFQ) and a short-form FFQ for polyphenol intake…
View article: Effect of Ingestion of Medium-Chain Triglycerides on Substrate Oxidation during Aerobic Exercise Could Depend on Sex Difference in Middle-Aged Sedentary Persons
Effect of Ingestion of Medium-Chain Triglycerides on Substrate Oxidation during Aerobic Exercise Could Depend on Sex Difference in Middle-Aged Sedentary Persons Open
Fat oxidation (FAO) during aerobic exercise and whole-body FAO via lipid intake are thought to be important for the maintenance of health, such as the prevention of type 2 diabetes and obesity in sedentary persons in their 40s and 50s. Med…
View article: Associations Between Plasma Kinin B1 Receptor Levels and the Presence and Severity of Coronary Artery Disease
Associations Between Plasma Kinin B1 Receptor Levels and the Presence and Severity of Coronary Artery Disease Open
Aim: Kinin B1 receptor (KB1R) was shown to be up-regulated in human carotid atherosclerotic lesions. Serum KB1R levels were also reported to be high in patients with stroke. However, KB1R deficiency increased atherosclerotic lesions. There…
View article: Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease
Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease Open
Aims . Atherosclerotic disease, such as coronary artery disease (CAD), is recognized to be associated with inflammation and oxidative stress. We investigated the association between CAD and plasma levels of sestrin2 which is one of the str…
View article: Associations between Green Tea Consumption and Coffee Consumption and the Prevalence of Coronary Artery Disease
Associations between Green Tea Consumption and Coffee Consumption and the Prevalence of Coronary Artery Disease Open
Green tea and coffee contain various bioactive compounds (e.g., polyphenols), and their consumption has been proposed to decrease the risk of cardiovascular diseases. Here, we investigated the associations between the consumption of green …
View article: High Plasma Levels of Soluble Talin-1 in Patients with Coronary Artery Disease
High Plasma Levels of Soluble Talin-1 in Patients with Coronary Artery Disease Open
Aims. Talin-1 is a cytoskeletal protein that binds integrin, thereby leading to integrin activation and affecting focal adhesions. Recently, talin-1 expression was reported to be downregulated in human atherosclerotic plaques. However, blo…
View article: Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes
Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes Open
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease, sometimes ranges from simple steatosis to nonalcoholic steatohepatitis (NASH). Various hits including excessive hepatic steatosis, oxidativ…
View article: <p>Consumption of Polyphenols in Coffee and Green Tea Alleviates Skin Photoaging in Healthy Japanese Women</p>
Consumption of Polyphenols in Coffee and Green Tea Alleviates Skin Photoaging in Healthy Japanese Women Open
Higher consumption of TPs may be beneficial to alleviate photoaging of the skin, and coffee as well as green tea contribute to suppress skin hyperpigmentation through adding large amounts of TPs in the diet.
View article: Correction to: Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study
Correction to: Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study Open
The original version of this article unfortunately contained a mistake.
View article: High Plasma Levels of Legumain in Patients with Complex Coronary Lesions
High Plasma Levels of Legumain in Patients with Complex Coronary Lesions Open
Plasma legumain levels were associated with the presence of complex coronary lesions.
View article: Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study
Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study Open
View article: Plasma Betatrophin Levels and Carotid Atherosclerosis
Plasma Betatrophin Levels and Carotid Atherosclerosis Open
Aims. Betatrophin is a recently identified circulating adipokine that may affect lipid and glucose metabolism. However, the association between plasma betatrophin levels and carotid atherosclerosis has not been elucidated. Methods. We inve…
View article: Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3
Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3 Open
Aronia berry extract could exert anti-atherosclerotic effects on TNF-α-induced inflammation through inhibition of STAT3/IRF1 pathway in vascular endothelial cells.