Kazuo Sonoki
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View article: Short-Chain Fatty Acids Suppress MCP-1 and Cellular Aging Induced by Lipopolysaccharides under High-Concentration Glucose
Short-Chain Fatty Acids Suppress MCP-1 and Cellular Aging Induced by Lipopolysaccharides under High-Concentration Glucose Open
Background: High glucose levels, as observed in diabetic patients, enhances the inflammatory response of Porphyromonas gingivalis-Lipopolysaccharide (Pg-LPS) in various cell types and may thus worsen atherosclerosis and other inflammatory …
View article: Correlation of Salivary Occult Blood with the Plasma Concentration of Branched-Chain Amino Acids: A Cross-Sectional Study
Correlation of Salivary Occult Blood with the Plasma Concentration of Branched-Chain Amino Acids: A Cross-Sectional Study Open
Background: Plasma branched-chain amino acids (BCAA) levels are predictors of glycometabolic disorders, leading to diabetes. Microbes, including periodontal pathogens, are thought to be associated with elevated plasma BCAA levels. This stu…
View article: The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State
The Alteration of Brain Function by the Improvement of Periodontal Tissues and Occlusal State Open
Objective . In this study, we have introduced a case in which the effective blood oxygenation level‐dependent signal on functional magnetic resonance imaging (fMRI) was altered by the improvement of periodontal tissue and occlusal function…
View article: Effectiveness of Tongue cleaning as a component of Oral care on the fasting Plasma Desacyl Ghrelin concentration in very elderly individuals: Six-Week Randomized controlled trial
Effectiveness of Tongue cleaning as a component of Oral care on the fasting Plasma Desacyl Ghrelin concentration in very elderly individuals: Six-Week Randomized controlled trial Open
To investigate whether tongue cleaning as a component of oral care affects the fasting plasma desacyl ghrelin concentrations in elderly people with the peak expiratory flow (PEF) as the measure of coughing ability. This randomized controll…
View article: Swallowing function and the incidence of fever in older residents with special care needs: a one-year longitudinal prospective study
Swallowing function and the incidence of fever in older residents with special care needs: a one-year longitudinal prospective study Open
Background Infectious diseases including aspiration pneumonia are the most frequent causes of fever, common in older residents of nursing homes. We investigated whether swallowing dysfunction was related to fever in such residents. Methods…
View article: Effects of periodontal disease and diabetes mellitus on the life prognosis in an 80-year-old community population
Effects of periodontal disease and diabetes mellitus on the life prognosis in an 80-year-old community population Open
80歳地域住民において糖尿病と歯周病が生命予後に影響するのか検討した。平成10年福岡県北九州市とその近郊に在住する80歳697名が歯科・内科検診を受診した。697名の12年後の生存調査から，全死亡および肺炎，循環器疾患，悪性腫瘍による死亡に分けて解析を行った。4 mm以上の歯周ポケットのある歯数が0～4本を軽症歯周病群（526名，無歯顎者を含む），5本以上を重症歯周病群（169名）とした。糖尿病群は血糖値200 mg/dl以上または糖尿病の既往歴や血糖降下剤を服用している7…