Kazuya Moriwake
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View article: Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information
Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information Open
A risk stratification system based on liquid biopsy, specialised for each phase (pre- and post-surgery), has been proven to be a useful, simple, and practical prognostic prediction clinical tool to determine the optimal multidisciplinary t…
View article: ADAR1 as a prognostic marker for patients with colorectal cancer and synchronous liver metastasis and a predictor of chemotherapy efficacy
ADAR1 as a prognostic marker for patients with colorectal cancer and synchronous liver metastasis and a predictor of chemotherapy efficacy Open
RNA editing by adenosine deaminase acting on RNA (ADAR) enzymes plays a role in cancer progression. However, its clinical significance in metastatic colorectal cancer (CRC) remains unclear. This study aimed to evaluate whether ADAR1 expres…
View article: ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer
ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer Open
View article: Predictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients
Predictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients Open
Low NLR and high ADAR1 were predictive markers for a positive response to the FTD/TPI plus bevacizumab regimen associated with prolonged PFS. The FTD/TPI plus bevacizumab regimen should be proactively implemented in the low NLR and high AD…
View article: The ingenious drainage system controls persistent duodenal stump fistula due to pancreatic fistula after subtotal gastrectomy for advanced gastric cancer
The ingenious drainage system controls persistent duodenal stump fistula due to pancreatic fistula after subtotal gastrectomy for advanced gastric cancer Open
Duodenal stump fistula (DSF) is a dangerous complication after gastrectomy. There is no consensus on the management of DSF. Sometimes, emergency surgery may be necessary. We present the case who underwent subtotal gastrectomy with Roux-en-…
View article: Subtotal esophagectomy and concurrent reconstruction with free jejunal flap for primary esophageal cancer after pancreatoduodenectomy
Subtotal esophagectomy and concurrent reconstruction with free jejunal flap for primary esophageal cancer after pancreatoduodenectomy Open
Background Pancreatoduodenectomy and subtotal esophagectomy are widely considered the most invasive and difficult surgical procedures in gastrointestinal surgery. Subtotal esophagectomy after pancreatoduodenectomy is expected to be extreme…
View article: BRAF-mutant microsatellite-stable rectal cancer with acquired KRAS mutation leading to drug resistance in liver metastasis
BRAF-mutant microsatellite-stable rectal cancer with acquired KRAS mutation leading to drug resistance in liver metastasis Open
View article: Optimal Case Selection and Required Experience in Training for Elective Laparoscopic Cholecystectomy among Surgery Residents
Optimal Case Selection and Required Experience in Training for Elective Laparoscopic Cholecystectomy among Surgery Residents Open
目的：外科専攻医が安全に待機的腹腔鏡下胆囊摘出術（laparoscopic cholecystectomy；以下，LCと略記）を執刀し修練認定を得るために必要な症例数と適切な執刀症例選択の指標について検討する．方法：2018年4月から2021年12月の期間に当科専攻医5名が執刀した待機的LC症例124例を対象とした．それぞれの専攻医の手術時間について累積和（cumulative sum；以下，CUSUMと略記）法を用いてラーニングカーブを作成し習熟に必要な症例数について検討…
View article: A case report of splenic injury related to colonoscopy: Fortunately treated with conservative treatment
A case report of splenic injury related to colonoscopy: Fortunately treated with conservative treatment Open
Colonoscopy is a common procedure for screening of colon cancer. Although complications are rare, recently there have been reports of splenic injury associated with colonoscopy. Its causes are not clear. Herein, we report an 84‐year‐old ma…
View article: Safe and curative modified two-stage operation for T4 esophageal cancer after definitive chemoradiotherapy: a case report
Safe and curative modified two-stage operation for T4 esophageal cancer after definitive chemoradiotherapy: a case report Open