Rui Bi
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View article: Evaluating the Effectiveness of Insecticides on Spotted Lanternfly Lycorma delicatula (Hemiptera: Fulgoridae) in Kiwifruit
Evaluating the Effectiveness of Insecticides on Spotted Lanternfly Lycorma delicatula (Hemiptera: Fulgoridae) in Kiwifruit Open
The spotted lanternfly (SLF), Lycorma delicatula (Hemiptera: Fulgoridae), has invaded several countries and caused significant losses to agricultural economy, especially in grapes, apples and kiwifruit production. Currently, chemical contr…
View article: Epithelial characteristics of ovarian clear cell carcinoma at single-cell resolution
Epithelial characteristics of ovarian clear cell carcinoma at single-cell resolution Open
View article: The -124C>T Mutation of the TERT Promoter Indicates Favorable Prognosis in Ovarian Clear Cell Carcinoma: A Single Institutional Study in China
The -124C>T Mutation of the TERT Promoter Indicates Favorable Prognosis in Ovarian Clear Cell Carcinoma: A Single Institutional Study in China Open
Background: Ovarian clear cell carcinoma (OCCC) is characterized by chemoresistance and poor prognosis in advanced or recurrent cases. This study aimed to find specific prognostic markers for OCCC. Methods: We analyzed 169 OCCC patients fo…
View article: Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling
Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling Open
View article: Epigenetic characterization of adult rhesus monkey spermatogonial stem cells identifies key regulators of stem cell homeostasis
Epigenetic characterization of adult rhesus monkey spermatogonial stem cells identifies key regulators of stem cell homeostasis Open
Spermatogonial stem cells (SSCs) play crucial roles in the preservation of male fertility. However, successful ex vivo expansion of authentic human SSCs remains elusive due to the inadequate understanding of SSC homeostasis regulation. Usi…
View article: Clinical characteristics and genomic profiling of outpatients with endometrial cancer at a Chinese tertiary cancer center
Clinical characteristics and genomic profiling of outpatients with endometrial cancer at a Chinese tertiary cancer center Open
Outpatients department gathered a considerable proportion of recurrent patients with complex genomic features. Patients with worse prognosis could be well studied, and anti-PD1 therapy was a promising salvage therapy in the real world.
View article: TRPS1, a sensitive marker for different histological and molecular types of breast cancer
TRPS1, a sensitive marker for different histological and molecular types of breast cancer Open
View article: Exercise Enhances Cardiomyocytic Mitochondrial Homeostasis to Alleviate Left Ventricular Dysfunction in Pressure Overload-Induced Remodelling
Exercise Enhances Cardiomyocytic Mitochondrial Homeostasis to Alleviate Left Ventricular Dysfunction in Pressure Overload-Induced Remodelling Open
Background: This study aims to explore how exercise enhances mitochondrial regulation and mitigates pathological cardiac hypertrophy. Methods: Rat groups were assigned as CN, sham, SC, and SE. A bioinformatics analysis was conducted to unc…
View article: Germline Mutational Landscape and Novel Targetable <i>RAD51D</i> Variant in Chinese Patients With Ovarian Cancer
Germline Mutational Landscape and Novel Targetable <i>RAD51D</i> Variant in Chinese Patients With Ovarian Cancer Open
PURPOSE Genetic variants of ovarian cancer (OV) show ethnic differences, but data from the Chinese population are still insufficient. Here, we elucidate the inheritance landscape in Chinese patients with OV and examine the functional impli…
View article: Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics
Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics Open
View article: circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis
circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis Open
View article: Butyrate attenuates the stemness of lung cancer cells through lysosome Fe2+- and SLC7A11-mediated ferroptosis
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe2+- and SLC7A11-mediated ferroptosis Open
View article: Response to anti-HER2 neoadjuvant chemotherapy in HER2-positive invasive breast cancers with different HER2 FISH patterns
Response to anti-HER2 neoadjuvant chemotherapy in HER2-positive invasive breast cancers with different HER2 FISH patterns Open
Aims Human epidermal growth factor receptor 2 (HER2)-positive patients with breast cancer may have different HER2/CEP17 ratios and HER2 copy numbers, with inconsistent responses to anti-HER2 neoadjuvant chemotherapy (NACT). Our study aimed…
View article: The -124C&gt;T mutation of TERT promoter indicated a favorable prognosis in OCCC: a monoinstitutional study in China
The -124C>T mutation of TERT promoter indicated a favorable prognosis in OCCC: a monoinstitutional study in China Open
Purpose Ovarian clear cell carcinoma (OCCC) is the second most common type of epithelial ovarian cancer. Patients with advanced or recurrent OCCC were resistant to chemotherapy and had poor prognosis. The purpose of this study was to ident…
View article: A germline heterozygous<i>POLQ</i>nonsense mutation causes hereditary colorectal cancer
A germline heterozygous<i>POLQ</i>nonsense mutation causes hereditary colorectal cancer Open
The causal genes for a large proportion of hereditary colorectal adenomas and early-onset colorectal cancer (CRC) remain to be identified. Here, we identified a germline heterozygous stop-gain mutation p.Arg1953X (rs150312701) of the POLQ …
View article: Study of tree shrew biology and models: A booming and prosperous field for biomedical research
Study of tree shrew biology and models: A booming and prosperous field for biomedical research Open
The tree shrew ( Tupaia belangeri) has long been proposed as a suitable alternative to non-human primates (NHPs) in biomedical and laboratory research due to its close evolutionary relationship with primates. In recent years, signif…
View article: Supplementary Figure 1 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 1 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
BATF2 regulates targets of c-Jun/AP-1.
View article: Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Enhanced expression of MET correlates with progression in human CRC.
View article: Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
IC50 determination of PF-04217903 and IFN-β in LoVo and SW620 cells.
View article: Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Purpose: BATF2, a novel IFN-stimulated gene, inhibits tumor cell proliferation, invasion, and migration. The objectives of this study were to determine how BATF2 expression is associated with colorectal cancer progression and…
View article: Supplementary Figure 5 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 5 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
BATF2 is an IFN-stimulated gene.
View article: Supplementary Figure 7 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 7 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
IFN-β and MET inhibitors enhance apoptosis but inhibit the proliferation of CRC cells.
View article: Supplementary Figure 3 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 3 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
siMET transfection arrests proliferation and migration of CRC cells.
View article: Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Supplementary Table 1. The correlation of BATF2 expression with clinicopathological status in 148 patients with colorectal cancer. Supplementary Table 2. Multivariate Cox proportional hazard analysis of prognostic variables in CRC patients…
View article: Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Supplementary Table 1. The correlation of BATF2 expression with clinicopathological status in 148 patients with colorectal cancer. Supplementary Table 2. Multivariate Cox proportional hazard analysis of prognostic variables in CRC patients…
View article: Supplementary Figure 7 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 7 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
IFN-β and MET inhibitors enhance apoptosis but inhibit the proliferation of CRC cells.
View article: Supplementary Figure 3 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 3 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
siMET transfection arrests proliferation and migration of CRC cells.
View article: Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
IC50 determination of PF-04217903 and IFN-β in LoVo and SW620 cells.
View article: Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Enhanced expression of MET correlates with progression in human CRC.
View article: Supplementary Figure 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
siMET transfection arrests invasion of CRC cells.