Kecheng Li
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View article: Pan-cancer analysis reveals that tumor microbiomes generate specific epitopes through transcriptional reprogramming
Pan-cancer analysis reveals that tumor microbiomes generate specific epitopes through transcriptional reprogramming Open
The therapeutic promise of tumor microbial peptides faces a critical safety paradox: tumors and peritumor tissues harbor compositionally similar microbiomes, yet safe immunotherapy demands tumor-specific targeting. We performed comprehensi…
View article: Male Infertility Management: A Critical Appraisal of Clinical Practice Guidelines With the AGREE II Instrument
Male Infertility Management: A Critical Appraisal of Clinical Practice Guidelines With the AGREE II Instrument Open
To systematically evaluate the quality of both domestic and international clinical practice guidelines for male infertility using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) tool, identify methodological shortcoming…
View article: Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics
Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics Open
The findings highlight the bidirectional modulation of phosphorylation in opsins as a potential mechanism linking optical factors from induced myopia and hyperopia to the molecular signaling processes that regulate ocular growth and adapta…
View article: Loss of C-Terminal Coiled-Coil Domains in SDCCAG8 Impairs Centriolar Satellites and Causes Defective Sperm Flagellum Biogenesis and Male Fertility
Loss of C-Terminal Coiled-Coil Domains in SDCCAG8 Impairs Centriolar Satellites and Causes Defective Sperm Flagellum Biogenesis and Male Fertility Open
Sperm flagellum defects are tightly associated with male infertility. Centriolar satellites are small multiprotein complexes that recruit satellite proteins to the centrosome and play an essential role in sperm flagellum biogenesis, but th…
View article: Plasma exosomal tsRNA may be used as a marker for differential diagnosis of benign and malignant pulmonary nodules
Plasma exosomal tsRNA may be used as a marker for differential diagnosis of benign and malignant pulmonary nodules Open
View article: Identification of anoikis-related subtypes and a risk score prognosis model, the association with TME landscapes and therapeutic responses in hepatocellular carcinoma
Identification of anoikis-related subtypes and a risk score prognosis model, the association with TME landscapes and therapeutic responses in hepatocellular carcinoma Open
Introduction Anoikis is a distinct form of programmed cell death, differing from classical apoptosis, and its role in malignant tumor progression, particularly in hepatocellular carcinoma (HCC), remains insufficiently understood. This stud…
View article: Sensing-actuating performance of flexible piezoelectric composites by component optimization
Sensing-actuating performance of flexible piezoelectric composites by component optimization Open
View article: Preparation of Chitooligosaccharides with Specific Sequence Arrangement and Their Effect on Inducing Salt Resistance in Wheat Seedlings
Preparation of Chitooligosaccharides with Specific Sequence Arrangement and Their Effect on Inducing Salt Resistance in Wheat Seedlings Open
Chitooligosaccharides (COS) exhibits good activity of inducing plant resistance, but the structure–activity relationship is still unclear. In this study, chitin oligosaccharides (CHOS) with a degree of polymerization (DP) of 2~6 were used …
View article: Analysis of Current Status of Clinical Trial Registrations in Andrological Diseases: Insights from ClinicalTrials.gov and ICTRP Databases
Analysis of Current Status of Clinical Trial Registrations in Andrological Diseases: Insights from ClinicalTrials.gov and ICTRP Databases Open
This study aims to analyze the registration information and outcome transparency for five common andrological diseases, as well as the factors influencing result availability. A comprehensive search was performed on ClinicalTrials.gov and …
View article: Proteogenomics Reveals Microproteins in Activated T Cells
Proteogenomics Reveals Microproteins in Activated T Cells Open
Noncanonical micropeptides, or called novel microproteins, i.e., polypeptides mostly under 10 kDa, are encoded by genomic sequences that have been previously annotated as noncoding but now known as small open reading frames (sORFs). The re…
View article: Design of Compostable and Recyclable Modified Soybean Oil-Coated Paper with Enhanced Water and Oil Resistance
Design of Compostable and Recyclable Modified Soybean Oil-Coated Paper with Enhanced Water and Oil Resistance Open
View article: Investigation of monosaccharide colorimetric efficiency by phenol-sulfuric acid method and optimization of quantitative models for polysaccharides
Investigation of monosaccharide colorimetric efficiency by phenol-sulfuric acid method and optimization of quantitative models for polysaccharides Open
View article: Influence of microstructure on the wettability of tobacco leaves: a theoretical model and quantitative analysis
Influence of microstructure on the wettability of tobacco leaves: a theoretical model and quantitative analysis Open
Wettability has widespread applications in everyday life such as waterproof clothing, moisture-proof materials, and self-cleaning surfaces. It is also a common phenomenon observed in plants like the lotus, where superhydrophobicity is prim…
View article: R2R3-MYB Gene Family in Coptis teeta Wall.: Genome-Wide Identification, Phylogeny, Evolutionary Expansion, and Expression Analyses during Floral Development
R2R3-MYB Gene Family in Coptis teeta Wall.: Genome-Wide Identification, Phylogeny, Evolutionary Expansion, and Expression Analyses during Floral Development Open
The R2R3-MYB gene family represents a widely distributed class of plant transcription factors. This gene family plays an important role in many aspects of plant growth and development. However, the characterization of R2R3-MYB genes presen…
View article: Development and Validation of an Interpretable Machine Learning Model for Early Prognosis Prediction in ICU Patients with Malignant Tumors and Hyperkalemia
Development and Validation of an Interpretable Machine Learning Model for Early Prognosis Prediction in ICU Patients with Malignant Tumors and Hyperkalemia Open
This study aims to develop and validate a machine learning (ML) predictive model for assessing mortality in patients with malignant tumors and hyperkalemia (MTH). We extracted data on patients with MTH from the Medical Information Mart for…
View article: Impact of uniaxial cyclic stretching on matrix-associated endothelial cell responses
Impact of uniaxial cyclic stretching on matrix-associated endothelial cell responses Open
View article: Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach Open
Diabetic foot ulcers (DFUs) are a prevalent and profoundly debilitating complication that afflicts individuals with diabetes mellitus (DM). These ulcers are associated with substantial morbidity, recurrence rates, disability, and mortality…
View article: Synthesis of Water-Dispersible Poly(dimethylsiloxane) and Its Potential Application in the Paper Coating Industry as an Alternative for PFAS-Coated Paper and Single-Use Plastics
Synthesis of Water-Dispersible Poly(dimethylsiloxane) and Its Potential Application in the Paper Coating Industry as an Alternative for PFAS-Coated Paper and Single-Use Plastics Open
Polyethylene-, polyvinylidene chloride-, and per- and polyfluoroalkyl substance-coated paper generate microplastics or fluorochemicals in the environment. Here, we report an approach for the development of oil-resistant papers using an env…
View article: Performance of ChatGPT on Chinese Master’s Degree Entrance Examination in Clinical Medicine
Performance of ChatGPT on Chinese Master’s Degree Entrance Examination in Clinical Medicine Open
Background ChatGPT is a large language model designed to generate responses based on a contextual understanding of user queries and requests. This study utilised the entrance examination for the Master of Clinical Medicine in Traditional C…
View article: Association between weekend catch-up sleeping and BMI of the United States population from 2017 to 2018
Association between weekend catch-up sleeping and BMI of the United States population from 2017 to 2018 Open
Background Obesity represents a major public health issue worldwide. In this study, we aimed to investigate the association between weekend catch-up sleep (CUS) and BMI. Method Our data were derived from the National Health and Nutrition E…
View article: Association Between Depression and the Risk of Osteoporosis of the United States Adult Population: a cross-sectional study
Association Between Depression and the Risk of Osteoporosis of the United States Adult Population: a cross-sectional study Open
Background Adults frequently experience depression and osteoporosis as mental diseases. lt is yet unknown, nevertheless, how depression affects one's risk for osteoporosis. Therefore, this article aims to investigate the relationship betwe…
View article: Chitin extraction from crab shells by two-step fermentation with Lacticanttacllus pantarum and Pseudomonas aeruginosa
Chitin extraction from crab shells by two-step fermentation with Lacticanttacllus pantarum and Pseudomonas aeruginosa Open
There are few reports on the extraction of chitin from crab shells using microbiological methods. In this work, the strain Lacticanttacllus pantarum (LA01) for demineralization (DM) and the strain Pseudomonas aeruginosa (PS01) for deprotei…
View article: Serum amyloid beta 42 levels correlated with metabolic syndrome and its components
Serum amyloid beta 42 levels correlated with metabolic syndrome and its components Open
Introduction Beta-amyloid accumulation in the brain appears to be a key initiating event in Alzheimer’s disease (AD), and factors associated with increased deposition of beta-amyloid are of great interest. Enhanced deposition of amyloid-β …
View article: Bio‐Inspired Microreactors Continuously Synthesize Glucose Precursor from CO<sub>2</sub> with an Energy Conversion Efficiency 3.3 Times of Rice (Adv. Sci. 6/2024)
Bio‐Inspired Microreactors Continuously Synthesize Glucose Precursor from CO<sub>2</sub> with an Energy Conversion Efficiency 3.3 Times of Rice (Adv. Sci. 6/2024) Open
Bio‐Inspired Microreactors Inspired by the Chinese legend of Shen Nong, the image portrays him using magical powers to integrate enzyme/polyethyleneimine assembly structures, which mimics thylakoid structures, into a microfluidic chip to c…
View article: Growth and morphogenesis of an everted tubular biological tissue
Growth and morphogenesis of an everted tubular biological tissue Open
Eversion, a ubiquitous phenomenon in living organisms, significantly contributes to the growth and morphogenesis of soft biological tissues and organs. In this study, we examine the role of elasticity and geometry in the morphogenesis of e…
View article: Factors influencing wettability and surface/interface mechanics of plant surfaces: a review
Factors influencing wettability and surface/interface mechanics of plant surfaces: a review Open
A wide variety of abundant plant leaves exist in nature, and the wettability of their surfaces is formed to adapt to diverse external environments. In this paper we will focus on the factors influencing the wettability of various plant lea…
View article: Bio‐Inspired Microreactors Continuously Synthesize Glucose Precursor from CO<sub>2</sub> with an Energy Conversion Efficiency 3.3 Times of Rice
Bio‐Inspired Microreactors Continuously Synthesize Glucose Precursor from CO<sub>2</sub> with an Energy Conversion Efficiency 3.3 Times of Rice Open
Excessive CO 2 and food shortage are two grand challenges of human society. Directly converting CO 2 into food materials can simultaneously alleviate both, like what green crops do in nature. Nevertheless, natural photosynthesis has a limi…
View article: Prognostic value of high-sensitivity cardiac troponin for major adverse cardiovascular events in patients with diabetes: a systematic review and meta-analysis
Prognostic value of high-sensitivity cardiac troponin for major adverse cardiovascular events in patients with diabetes: a systematic review and meta-analysis Open
Background High-sensitivity cardiac troponin (hs-cTn) is associated with cardiovascular outcomes in the general population, but the prognostic value of hs-cTn in the diabetic population remains inconclusive. This study aimed to systematica…
View article: Effects of Scallop Visceral Mass and Mantle as Dietary Supplements on the Growth, Immune Response and Intestinal Microflora of Juvenile Sea Cucumber Apostichopus japonicus
Effects of Scallop Visceral Mass and Mantle as Dietary Supplements on the Growth, Immune Response and Intestinal Microflora of Juvenile Sea Cucumber Apostichopus japonicus Open
Scallop visceral mass and mantle are aquatic byproducts and waste, but they have high contents of protein. In this study, scallop visceral mass and mantle were used as supplements in the diet of juvenile sea cucumber (A. japonicus) and the…
View article: Association Between Depression and Osteoporosis of the United States population: a cross-sectional study
Association Between Depression and Osteoporosis of the United States population: a cross-sectional study Open
Depression and osteoporosis both are common mental illness for older people and the relationship between osteoporosis and depression is still unclear. This article aims to determine the relationship between depression and osteoporosis amon…