Keegan R Paulson
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View article: Homodimeric Granzyme A Opsonizes <i>Mycobacterium tuberculosis</i> and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14
Homodimeric Granzyme A Opsonizes <i>Mycobacterium tuberculosis</i> and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14 Open
Mycobacterium tuberculosis (Mtb)-specific γ9δ2 T cells secrete granzyme A (GzmA) protective against intracellular Mtb growth. However, GzmA-enzymatic activity is unnecessary for pathogen inhibition, and the mechanisms of GzmA-mediated prot…