Kei‐ichi Uchiya
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View article: Genotyping and drug susceptibility patterns of Mycobacterium avium subsp. hominissuis isolates from different hosts
Genotyping and drug susceptibility patterns of Mycobacterium avium subsp. hominissuis isolates from different hosts Open
Mycobacterium avium subsp. hominissuis (MAH) causes mainly pulmonary infection in immunocompetent hosts, disseminated infection in immunocompromised hosts, such as individuals infected with human immunodeficiency virus (HIV), and infection…
View article: Longitudinal Trend in Antimicrobial Susceptibility among <i>Haemophilus influenzae</i>: A Single-Centre Study in Japan
Longitudinal Trend in Antimicrobial Susceptibility among <i>Haemophilus influenzae</i>: A Single-Centre Study in Japan Open
Haemophilus influenzae presents significant concerns regarding antimicrobial resistance. The circumstances surrounding H. influenzae have been changing owing to changes in antimicrobial usage. In the present study, to determine the current…
View article: Molecular characterization of a novel putative pathogen, <i>Streptococcus nakanoensis</i> sp. nov., isolated from sputum culture
Molecular characterization of a novel putative pathogen, <i>Streptococcus nakanoensis</i> sp. nov., isolated from sputum culture Open
Reports of novel species of α-hemolytic Streptococcus have increased recently. However, limited information exists regarding the pathogenicity of these species, with the exception of Streptococcus pneumoniae and Streptococcus pseudopneumon…
View article: Development of a rapid detection method for the macrolide resistance gene in <i>Mycobacterium avium</i> using the amplification refractory mutation system–loop-mediated isothermal amplification method
Development of a rapid detection method for the macrolide resistance gene in <i>Mycobacterium avium</i> using the amplification refractory mutation system–loop-mediated isothermal amplification method Open
Macrolide antibiotics such as clarithromycin (CLR) and azithromycin are the key drugs used in multidrug therapy for Mycobacterium avium complex (MAC) diseases. For these antibacterial drugs, drug susceptibility has been correlated with cli…
View article: The Association between Transformation Ability and Antimicrobial Resistant Potential in <i>Haemophilus influenzae</i>
The Association between Transformation Ability and Antimicrobial Resistant Potential in <i>Haemophilus influenzae</i> Open
The prevalence of quinolone low-susceptible Haemophilus influenzae has increased in Japan. Low quinolone susceptibility is caused by point mutations in target genes; however, it can also be caused by horizontal gene transfer via natural tr…
View article: A Rapid Screening Assay for Clarithromycin-Resistant Mycobacterium avium Complex Using Melting Curve Analysis with Nonfluorescent Labeled Probes
A Rapid Screening Assay for Clarithromycin-Resistant Mycobacterium avium Complex Using Melting Curve Analysis with Nonfluorescent Labeled Probes Open
Since macrolide antibiotics such as clarithromycin or azithromycin are key drugs in multidrug therapy for Mycobacterium avium complex (MAC) lung diseases, the rapid detection of macrolide-resistant MAC strains has important implications fo…
View article: Salmonella fimbrial protein StcD induces cyclooxygenase-2 expression via Toll-like receptor 4
Salmonella fimbrial protein StcD induces cyclooxygenase-2 expression via Toll-like receptor 4 Open
StcD is a pathogen-associated molecular pattern of S. enterica serovar Typhimurium that is recognized by TLR4 and plays a significant role in the induction of COX-2 expression in macrophages.
View article: 1654. Evaluation of a rapid detection method of clarithromycin resistance genes in <i>Mycobacterium avium</i> using the Amplification Refractory Mutation System-Loop-Mediated Isothermal Amplification method
1654. Evaluation of a rapid detection method of clarithromycin resistance genes in <i>Mycobacterium avium</i> using the Amplification Refractory Mutation System-Loop-Mediated Isothermal Amplification method Open
Background Clarithromycin (CLR) is the key drug in multidrug therapy for Mycobacterium avium complex (MAC) diseases and the only drug for which drug susceptibility is correlated with a clinical response in these diseases. In the case of CL…
View article: Correction to: Cell-free synthesis of functionally active HSPB5
Correction to: Cell-free synthesis of functionally active HSPB5 Open
View article: Cell-free synthesis of functionally active HSPB5
Cell-free synthesis of functionally active HSPB5 Open
View article: <i>Salmonella</i>Fimbrial Protein FimH Is Involved in Expression of Proinflammatory Cytokines in a Toll-Like Receptor 4-Dependent Manner
<i>Salmonella</i>Fimbrial Protein FimH Is Involved in Expression of Proinflammatory Cytokines in a Toll-Like Receptor 4-Dependent Manner Open
Type 1 fimbriae are proteinaceous filamentous structures present on bacterial surfaces and are mainly composed of the major fimbrial protein subunit FimA and the adhesive protein FimH, which is located at the tip of the fimbrial shaft. Her…
View article: Antibiotic Susceptibility and Genotyping of Mycobacterium avium Strains That Cause Pulmonary and Disseminated Infection
Antibiotic Susceptibility and Genotyping of Mycobacterium avium Strains That Cause Pulmonary and Disseminated Infection Open
Mycobacterium avium subsp. hominissuis mainly causes disseminated infection in immunocompromised hosts, such as individuals with human immunodeficiency virus (HIV) infection, and pulmonary infection in immunocompetent hosts. However, many …
View article: Characterization of a Novel Plasmid, pMAH135, from Mycobacterium avium Subsp. hominissuis
Characterization of a Novel Plasmid, pMAH135, from Mycobacterium avium Subsp. hominissuis Open
Mycobacterium avium complex (MAC) causes mainly two types of disease. The first is disseminated disease in immunocompromised hosts, such as individuals infected by human immunodeficiency virus (HIV). The second is pulmonary disease in indi…