Keiji Kinoshita
YOU?
Author Swipe
View article: Effects of targeted deletion of a 284 bp avian-specific highly conserved element within the <i>Sim1</i> gene on flight feather development in chickens
Effects of targeted deletion of a 284 bp avian-specific highly conserved element within the <i>Sim1</i> gene on flight feather development in chickens Open
Flight feathers represent a hallmark innovation of avian evolution. Recent comparative genomic analyses identified a 284 bp avian-specific highly conserved element (ASHCE) located within the eighth intron of the SIM bHLH transcription fact…
View article: PGC-based cryobanking, regeneration through germline chimera mating, and CRISPR/Cas9-mediated TYRP1 modification in indigenous Chinese chickens
PGC-based cryobanking, regeneration through germline chimera mating, and CRISPR/Cas9-mediated TYRP1 modification in indigenous Chinese chickens Open
Primordial germ cells (PGCs) are vital for producing sperm and eggs and are crucial for conserving chicken germplasm and creating genetically modified chickens. However, efforts to use PGCs for preserving native chicken germplasm and genet…
View article: PGC-based cryobanking, regeneration through germline chimera mating, and CRISPR/Cas9-mediated TYRP1 modification in indigenous Chinese chickens
PGC-based cryobanking, regeneration through germline chimera mating, and CRISPR/Cas9-mediated TYRP1 modification in indigenous Chinese chickens Open
Primordial germ cells (PGCs) are essential precursors for sperm and eggs. PGCs are highly reliable for conserving chicken germplasm and producing genetically modified chickens. Currently, efforts to conserve native chicken germplasm throug…
View article: Identification of variation in<i>Fibromelanosis</i>region on chromosome 20 for determining the purity of Indonesian Cemani chicken
Identification of variation in<i>Fibromelanosis</i>region on chromosome 20 for determining the purity of Indonesian Cemani chicken Open
Ayam Cemani is a local Indonesian chicken with heavy pigmentation in plumage colour, skin, eyes, and inner body organs. This trait with dermal hyperpigmentation is identical to Fibromelanosis ( Fm ) mutation in a Silkie chicken. The causal…
View article: Clinical features and treatment strategies of febrile urinary tract infection caused by extended-spectrum beta-lactamase–producing Enterobacteriaceae in children: a multicenter retrospective observational study in Japan
Clinical features and treatment strategies of febrile urinary tract infection caused by extended-spectrum beta-lactamase–producing Enterobacteriaceae in children: a multicenter retrospective observational study in Japan Open
ESBL-producing bacteria should be considered in children with recurrent UTIs and recent antibiotic use. Most children with fUTI experience clinical improvement regardless of the choice of antibiotic.
View article: Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail Open
The precursor of heme, protoporphyrin IX (PPIX), accumulates abundantly in the uteri of birds, such as Japanese quail, Coturnix japonica , which has brown-speckled eggshells; however, the molecular basis of PPIX production in the uterus re…
View article: 森田賞 《臨床研究部門》 大西卓磨
森田賞 《臨床研究部門》 大西卓磨 Open
View article: Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail Open
The precursor of heme, protoporphyrin IX (PPIX), accumulates abundantly in the uterus of birds, such as Japanese quail, Coturnix japonica , resulting in brown-speckled eggshells. The molecular basis of PPIX production in the uterus remains…
View article: Pertussis Transmission in a Hospital Office that was Confirmed on the Basis of Loop-mediated Isothermal Amplification
Pertussis Transmission in a Hospital Office that was Confirmed on the Basis of Loop-mediated Isothermal Amplification Open
Objective A hospital clerk developed whooping cough and its infectious condition throughout the work place was investigated to clarify the spread of pertussis infection using highly sensitive Loop-mediated isothermal amplification (LAMP).
View article: Clinical characteristics of pediatric febrile urinary tract infection in Japan
Clinical characteristics of pediatric febrile urinary tract infection in Japan Open
View article: Geographic Origin and Genetic Characteristics of Japanese Indigenous Chickens Inferred from Mitochondrial D-Loop Region and Microsatellite DNA Markers
Geographic Origin and Genetic Characteristics of Japanese Indigenous Chickens Inferred from Mitochondrial D-Loop Region and Microsatellite DNA Markers Open
Japanese indigenous chickens have a long breeding history, possibly beginning 2000 years ago. Genetic characterization of Japanese indigenous chickens has been performed using mitochondrial D-loop region and microsatellite DNA markers. The…
View article: Transcriptome analysis revealed misregulated gene expression in blastoderms of interspecific chicken and Japanese quail F1 hybrids
Transcriptome analysis revealed misregulated gene expression in blastoderms of interspecific chicken and Japanese quail F1 hybrids Open
Hybrid incompatibility, such as sterility and inviability, prevents gene flow between closely-related populations as a reproductive isolation barrier. F1 hybrids between chickens and Japanese quail (hereafter, referred to as quail), exhibi…
View article: Combined deletions of IHH and NHEJ1 cause chondrodystrophy and embryonic lethality in the Creeper chicken
Combined deletions of IHH and NHEJ1 cause chondrodystrophy and embryonic lethality in the Creeper chicken Open
View article: Diagnostic Usefulness of Loop-mediated Isothermal Amplification for Intrafamilial Pertussis Infection
Diagnostic Usefulness of Loop-mediated Isothermal Amplification for Intrafamilial Pertussis Infection Open
As a Bordetella pertussis gene test, the loop-mediated isothermal amplification (LAMP) method has become widely used for the diagnosis in clinical practice. The diagnostic usefulness of the LAMP method was investigated in 11 infant patient…
View article: Genetic diversity of 21 experimental chicken lines with diverse origins and genetic backgrounds
Genetic diversity of 21 experimental chicken lines with diverse origins and genetic backgrounds Open
The genetic characteristics and diversity of 21 experimental chicken lines registered with the National BioResource Project of Japan were examined using mitochondrial D-loop sequences and 54 microsatellite DNA markers. A total of 12 haplot…
View article: Nonsense mutation in PMEL is associated with yellowish plumage colour phenotype in Japanese quail
Nonsense mutation in PMEL is associated with yellowish plumage colour phenotype in Japanese quail Open
View article: The “Extended Brown” Plumage Color Mutant of Blue-Breasted Quail (<i>Coturnix chinensis</i>) is Associated with a Mutation in the Melanocortin 1-Receptor Gene (<i>MC1R</i>)
The “Extended Brown” Plumage Color Mutant of Blue-Breasted Quail (<i>Coturnix chinensis</i>) is Associated with a Mutation in the Melanocortin 1-Receptor Gene (<i>MC1R</i>) Open
The mutant plumage color "extended brown (EB)" of the blue-breasted quail was genetically investigated. Mating experiments revealed that the EB plumage is controlled by an autosomal, incompletely dominant allele, for which we propose the s…
View article: Detection of Mumps Virus Vaccine Strain in Breast Milk After Postpartum Vaccination
Detection of Mumps Virus Vaccine Strain in Breast Milk After Postpartum Vaccination Open
Objective: To clarify whether a lactating mother can give breast milk after vaccination for the mumps virus.
View article: Identification of TENP as the Gene Encoding Chicken Egg White Ovoglobulin G2 and Demonstration of Its High Genetic Variability in Chickens
Identification of TENP as the Gene Encoding Chicken Egg White Ovoglobulin G2 and Demonstration of Its High Genetic Variability in Chickens Open
Ovoglobulin G2 (G2) has long been known as a major protein constituent of chicken egg white. However, little is known about the biochemical properties and biological functions of G2 because the gene encoding G2 has not been identified. The…
View article: Embryonic development and inviability phenotype of chicken-Japanese quail F1 hybrids
Embryonic development and inviability phenotype of chicken-Japanese quail F1 hybrids Open
View article: コドン中のGAT(Asp)をAAT(Asn)に置換したニワトリのオボトランスフェリン変異株OTFBとOTFC
コドン中のGAT(Asp)をAAT(Asn)に置換したニワトリのオボトランスフェリン変異株OTFBとOTFC Open
View article: Chicken Ovotransferrin Variants OTF<sup>B</sup> and OTF<sup>C</sup> Harboring Substitution of GAT (Asp) to AAT (Asn) in the Codon 500 and their Antimicrobial Activity
Chicken Ovotransferrin Variants OTF<sup>B</sup> and OTF<sup>C</sup> Harboring Substitution of GAT (Asp) to AAT (Asn) in the Codon 500 and their Antimicrobial Activity Open
Chicken egg white ovotransferrin (OTF) has been reported to exist in three electrophoretic variants (OTFA, OTFB and OTFC). In this report, we identified a causal polymorphism between the OTFB and…
View article: Wild-type and mottled plumage phenotypes with two different <i>extended black</i> (<i>E</i>) backgrounds in Cochin bantam (CB) and Ehime-jidori (EJ).
Wild-type and mottled plumage phenotypes with two different <i>extended black</i> (<i>E</i>) backgrounds in Cochin bantam (CB) and Ehime-jidori (EJ). Open
(A) The wild-type (Mo+/−) (A-1) and mottled plumage (mo/mo) (A-2) in adult CB females with an E/E genetic background. (B) The wild-type (Mo+/−) (B-1) and mottled plumage (m…
View article: Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging
Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging Open
Oca2(p-cas) (oculocutaneous albinism II; pink-eyed dilution castaneus) is a coat color mutant gene on mouse chromosome 7 that arose spontaneously in wild Mus musculus castaneus mice. Mice homozygous for Oca2(p-cas) usually exhibit pink eye…
View article: Genetic Differentiation among Populations of the Kurokashiwa Breed of Indigenous Japanese Chickens Assessed by Microsatellite DNA Polymorphisms
Genetic Differentiation among Populations of the Kurokashiwa Breed of Indigenous Japanese Chickens Assessed by Microsatellite DNA Polymorphisms Open
The Kurokashiwa breed of native Japanese chickens is primarily reared in Shimane and Yamaguchi Prefectures, Japan. To reveal the genetic diversity and differentiation among the Kurokashiwa populations in both prefectures, 29 microsatellite…