Keir McCutcheon
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View article: ACE-Net: A-line coordinates encoding network for vascular structure segmentation in ultrasound images
ACE-Net: A-line coordinates encoding network for vascular structure segmentation in ultrasound images Open
Ultrasound (US) imaging enables the evaluation of vascular structures in real time, and it can provide morphological and pathological information during US-guided procedures. Automatic prediction of vascular structure boundaries can help c…
View article: Cardiac and Renal Comorbidities in Aging People Living With HIV
Cardiac and Renal Comorbidities in Aging People Living With HIV Open
Contemporary World Health Organization data indicates that ≈39 million people are living with the human immunodeficiency virus. Of these, 24 million have been reported to have successfully accessed combination antiretroviral therapy. In 19…
View article: Heart Failure-Related Outcomes in Patients with Left Ventricular Dysfunction Undergoing Percutaneous Chronic Total Occlusion Revascularization
Heart Failure-Related Outcomes in Patients with Left Ventricular Dysfunction Undergoing Percutaneous Chronic Total Occlusion Revascularization Open
In patients with reduced LV systolic function (ejection fraction, EF 40%), CTO PCI is a safe and effective procedure and successful CTO PCI is independently associated with a lower risk of HFH during follow-up. Further expansion of this c…
View article: In vivo validation of intra-coronary absolute flow measurements and comparison of reliability between different microvascular indices and the microvascular resistance reserve
In vivo validation of intra-coronary absolute flow measurements and comparison of reliability between different microvascular indices and the microvascular resistance reserve Open
Background Coronary microvascular dysfunction plays a major role in patients with cardiac ischemia without flow limiting epicardial coronary stenosis, takotsubo cardiomyopathy, aortic valve stenosis and heart failure with preserved ejectio…
View article: Unravelling the Fate of Coronary Artery Disease in Patients Undergoing Valve Replacement for Severe Aortic Valve Stenosis
Unravelling the Fate of Coronary Artery Disease in Patients Undergoing Valve Replacement for Severe Aortic Valve Stenosis Open
Severe aortic valve stenosis is the most frequent valve pathology in the western world and approximately 50% of these patients have concomitant coronary artery disease (CAD). Revascularization of proximal obstructive CAD in patients underg…
View article: Postdischarge prognostic significance of periprocedural myocardial injury after percutaneous intervention of chronic total occlusion
Postdischarge prognostic significance of periprocedural myocardial injury after percutaneous intervention of chronic total occlusion Open
Background The postdischarge prognostic implication of periprocedural myocardial injury in patients undergoing percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) remains scarcely studied. Aims The aim of this study…
View article: Arteriovenous Fistulae in Chronic Kidney Disease and the Heart: Physiological, Histological, and Transcriptomic Characterization of a Novel Rat Model
Arteriovenous Fistulae in Chronic Kidney Disease and the Heart: Physiological, Histological, and Transcriptomic Characterization of a Novel Rat Model Open
Background Arteriovenous fistulae (AVFs) are the gold standard for vascular access in those requiring hemodialysis but may put an extra hemodynamic stress on the cardiovascular system. The complex interactions between the heart, kidney, an…
View article: Sex differences in the impact of coronary artery disease on long-term survival after transcatheter aortic valve implantation
Sex differences in the impact of coronary artery disease on long-term survival after transcatheter aortic valve implantation Open
Background It has been suggested that the complexity of coronary artery disease (CAD) is a determinant of worse outcomes after transcatheter aortic valve implantation (TAVI). However, no data is available showing this applies equally to bo…
View article: Impact of Loading and Myocardial Mechanical Properties on Natural Shear Waves
Impact of Loading and Myocardial Mechanical Properties on Natural Shear Waves Open
View article: Coronary physiology to guide treatment of coronary artery disease in a patient with severe aortic valve stenosis: friend or foe? A case report
Coronary physiology to guide treatment of coronary artery disease in a patient with severe aortic valve stenosis: friend or foe? A case report Open
Background Severe aortic valve stenosis (AS) is the most frequent valve pathology in the developed world requiring intervention. Due to common factors in pathogenesis, patients with AS frequently have concomitant coronary artery disease (C…
View article: How well does shear wave elastography predict elevated filling pressures? a comparison to the current guideline algorithm
How well does shear wave elastography predict elevated filling pressures? a comparison to the current guideline algorithm Open
Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): University Hospitals (Uz) Leuven Background The assessment of left ventricular diastolic function is complex, as there is no single invasive para…
View article: IMR or CFR - Which parameter is better suited to determine microvascular disease in patients with severe aortic stenosis?
IMR or CFR - Which parameter is better suited to determine microvascular disease in patients with severe aortic stenosis? Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Research Foundation Flanders Background Chest pain in patients with severe aortic stenosis (AS) may result from the valve ste…
View article: Wits Journal of Clinical Medicine (Volume 4, Issue 3)
Wits Journal of Clinical Medicine (Volume 4, Issue 3) Open
View article: Climate Change and Cardiovascular Disease in Africa
Climate Change and Cardiovascular Disease in Africa Open
View article: Revascularization strategies in patients with multivessel coronary artery disease: a Bayesian network meta-analysis
Revascularization strategies in patients with multivessel coronary artery disease: a Bayesian network meta-analysis Open
Summary Treatment modalities for multivessel disease have rapidly evolved, yet the preferred strategy remains controversial. This meta-analysis compared outcomes after on-pump (ONCAB), off-pump coronary artery bypass grafting (OPCAB), perc…
View article: Efficacy of MAVIG X-Ray Protective Drapes in Reducing CTO Operator Radiation
Efficacy of MAVIG X-Ray Protective Drapes in Reducing CTO Operator Radiation Open
Background. The MAVIG X-ray protective drape (MXPD) has been shown to reduce operator radiation dose during percutaneous coronary interventions (PCI). Whether MXPDs are also effective in reducing operator radiation during chronic total occ…
View article: Contemporary Strategies and Outcomes of Dedicated Chronic Total Occlusion Percutaneous Coronary Intervention Programs: A Prospective Multicentre Registry
Contemporary Strategies and Outcomes of Dedicated Chronic Total Occlusion Percutaneous Coronary Intervention Programs: A Prospective Multicentre Registry Open
Background. The field of CTO PCI is expanding, but successful and safe percutaneous coronary intervention (PCI) of coronary chronic total occlusions (CTO) requires a substantial resource and experience investment. We aimed to assess tempor…
View article: Human Immunodeficiency Virus and Cardiovascular Disease: Revisiting the Inflammation–Thrombosis Axis
Human Immunodeficiency Virus and Cardiovascular Disease: Revisiting the Inflammation–Thrombosis Axis Open
There are more than 37 million people living with the human immunodeficiency virus (PLWH) worldwide with an estimated 2 million new infections occurring annually. Antiretroviral medication has dramatically prolonged the life expectancy of …
View article: Natural shear wave propagation speed is influenced by both changes in myocardial structural properties as well as loading conditions
Natural shear wave propagation speed is influenced by both changes in myocardial structural properties as well as loading conditions Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Research Foundation - Flanders (FWO) Background Shear wave elastography (SWE) is a promising tool for the non-invasive assess…
View article: Efficacy of MAVIG X-Ray Protective Drapes in Reducing Operator Radiation Dose in the Cardiac Catheterization Laboratory
Efficacy of MAVIG X-Ray Protective Drapes in Reducing Operator Radiation Dose in the Cardiac Catheterization Laboratory Open
Background: Interventional cardiologists are occupationally exposed to high doses of ionizing radiation. The MAVIG X-ray protective drape (MXPD) is a commercially available light weight, lead-free shield placed over the pelvic area of pati…
View article: Angiotensin-converting enzyme 2, sex differences, and COVID-19: The missing link
Angiotensin-converting enzyme 2, sex differences, and COVID-19: The missing link Open
View article: Heart team 2.0: A decision tree for minimally invasive and hybrid myocardial revascularization
Heart team 2.0: A decision tree for minimally invasive and hybrid myocardial revascularization Open
Recent years have seen an important shift in the target population for myocardial revascularization. Patients are increasingly presenting with more complex coronary artery disease (CAD), but also with multiple comorbidities and frailty. At…
View article: Correlation between Serum Markers of Adverse Left Ventricular Remodelling and Gene Expression Levels Measured in the Myocardial Tissue of Patients with Chronic Primary Mitral Regurgitation
Correlation between Serum Markers of Adverse Left Ventricular Remodelling and Gene Expression Levels Measured in the Myocardial Tissue of Patients with Chronic Primary Mitral Regurgitation Open
Background: Chronic primary mitral regurgitation (CPMR) is characterized by progressive myocardial hypertrophy, fibrosis and dilatation. Although molecular markers of adverse left ventricular (LV) remodelling have been identified in the pr…
View article: Resorbable magnesium scaffold: The learning curve continues…
Resorbable magnesium scaffold: The learning curve continues… Open
View article: COVID-19 and the Cardiovascular System: A Review
COVID-19 and the Cardiovascular System: A Review Open
CARDIOVASCULAR COMORBIDITIES AND COVID-19COVID-19 affects all age groups but seems to be more severe in older patients (over the age of 60 years) and in patients with hypertension, diabetes, obesity, chronic lung disease and underlying car…
View article: Dynamic Changes in the Molecular Signature of Adverse Left Ventricular Remodeling in Patients With Compensated and Decompensated Chronic Primary Mitral Regurgitation
Dynamic Changes in the Molecular Signature of Adverse Left Ventricular Remodeling in Patients With Compensated and Decompensated Chronic Primary Mitral Regurgitation Open
Background: There is no proven medical therapy that attenuates adverse left ventricular remodeling in patients with chronic primary mitral regurgitation (CPMR). Identification of molecular pathways important in the progression of left vent…
View article: Left ventricular remodelling in chronic primary mitral regurgitation: implications for medical therapy
Left ventricular remodelling in chronic primary mitral regurgitation: implications for medical therapy Open
Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodell…
View article: Long-term outcomes after percutaneous revascularization of complex coronary bifurcation lesions using a dedicated self-expanding biolimus-eluting stent system
Long-term outcomes after percutaneous revascularization of complex coronary bifurcation lesions using a dedicated self-expanding biolimus-eluting stent system Open
Percutaneous revascularization of complex bifurcation lesions with the AXXESS stent is safe and provides excellent long-term results, especially in non-LM lesions.
View article: Unusually aggressive immature neo-intimal hyperplasia causing in-stent restenosis
Unusually aggressive immature neo-intimal hyperplasia causing in-stent restenosis Open
This image illustrates a very unusual pattern of early and aggressive immature neo-intimal hyperplasia in a 52-year-old man with unstable angina, two months after deployment of a drug-eluting stent in the proximal left anterior descending …
View article: Etiology and Long‐Term Outcome of Patients Undergoing Pericardiocentesis
Etiology and Long‐Term Outcome of Patients Undergoing Pericardiocentesis Open
Background Pericardial effusions can be caused by a variety of disorders. The frequency of the underlying diseases varies with patient population; therefore, previously reported series are not necessarily representative of other population…