Keisuke Kawata
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View article: Editorial: Assessment and treatment interventions for traumatic brain injury
Editorial: Assessment and treatment interventions for traumatic brain injury Open
View article: Assessing the capability of the corneal blink reflex to display neurological changes following subconcussive head impacts
Assessing the capability of the corneal blink reflex to display neurological changes following subconcussive head impacts Open
Introduction This study examines the capability of detecting neurological changes caused by subconcussive head impacts by analyzing the blink reflex of an individual when they encounter puffs of air as a stimulus. Methods Following attriti…
View article: 20 (2A) Unlocking asymptomatic subconcussive brain injury: blood biomarkers of oligodendrocyte-derived exosomes in athletes
20 (2A) Unlocking asymptomatic subconcussive brain injury: blood biomarkers of oligodendrocyte-derived exosomes in athletes Open
View article: Effects of Lifetime Exposure to Sports-Related Head Impacts on Brain Injury and Inflammatory Blood Biomarkers Among Former Middle-Aged Athletes
Effects of Lifetime Exposure to Sports-Related Head Impacts on Brain Injury and Inflammatory Blood Biomarkers Among Former Middle-Aged Athletes Open
Repetitive head impacts from contact sports are associated with an increased risk of neurodegenerative conditions. While studies have examined acute and chronic outcomes in young and deceased athletes, research on middle-aged former athlet…
View article: Return-to-Learn for the K-12 Student: a Mixed-Methods Systematic Review
Return-to-Learn for the K-12 Student: a Mixed-Methods Systematic Review Open
Objective: Our aim was to perform a systematic review of Return-to-Learn literature with the intent of determining what items are necessary to form a comprehensive Return-to-Learn policy. Data Sources: We searched CINAHL, Embase, PubMed, S…
View article: Association of Auditory Interference and Ocular-Motor Response with Subconcussive Head Impacts in Adolescent Football Players
Association of Auditory Interference and Ocular-Motor Response with Subconcussive Head Impacts in Adolescent Football Players Open
The aim of this study was to examine whether neuro-ophthalmological function, as assessed by the King-Devick test (KDT), alters during a high school football season and to explore the role of auditory interference on the sensitivity of KDT…
View article: Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes
Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes Open
Introduction Repetitive head impacts (RHI) have been suggested to increase the risk of developing a neurodegenerative disease, and many of these individuals develop a preceding mental health diagnosis. Given the lack of studies among amate…
View article: A Pilot Study Investigating the Use of Serum Glial Fibrillary Acidic Protein to Monitor Changes in Brain White Matter Integrity After Repetitive Head Hits During a Single Collegiate Football Game
A Pilot Study Investigating the Use of Serum Glial Fibrillary Acidic Protein to Monitor Changes in Brain White Matter Integrity After Repetitive Head Hits During a Single Collegiate Football Game Open
Repetitive head hits (RHHs) in sports and military settings are increasingly recognized as a risk factor for adverse neurological outcomes, but they are not currently tracked. Blood-based biomarkers of concussion have recently been shown t…
View article: Effectiveness of biomedical interventions on the chronic stage of traumatic brain injury: a systematic review of randomized controlled trials
Effectiveness of biomedical interventions on the chronic stage of traumatic brain injury: a systematic review of randomized controlled trials Open
Traumatic brain injury (TBI), in any form and severity, can pose risks for developing chronic symptoms that can profoundly hinder patients’ work/academic, social, and personal lives. In the past 3 decades, a multitude of pharmacological, s…
View article: An approach for the analysis of axonal neuroinflammation by measuring dual biomarkers of oligodendrocytes and inflammatory cytokine in human plasma
An approach for the analysis of axonal neuroinflammation by measuring dual biomarkers of oligodendrocytes and inflammatory cytokine in human plasma Open
The myelin sheath surrounding axons is vulnerable to mechanical stresses after head injuries, as well as autoimmune attacks and degeneration in neurological disorders. Unfortunately, there is currently no effective method to assess these a…
View article: Cerebral Cortical Surface Structure and Neural Activation Pattern Among Adolescent Football Players
Cerebral Cortical Surface Structure and Neural Activation Pattern Among Adolescent Football Players Open
Importance Recurring exposure to head impacts in American football has garnered public and scientific attention, yet neurobiological associations in adolescent football players remain unclear. Objective To examine cortical structure and ne…
View article: Longitudinal Associations of Clinical and Biochemical Head Injury Biomarkers With Head Impact Exposure in Adolescent Football Players
Longitudinal Associations of Clinical and Biochemical Head Injury Biomarkers With Head Impact Exposure in Adolescent Football Players Open
Importance Consequences of subconcussive head impacts have been recognized, yet most studies to date have included small samples from a single site, used a unimodal approach, and lacked repeated testing. Objective To examine time-course ch…
View article: The modulatory role of cannabis use in subconcussive neural injury
The modulatory role of cannabis use in subconcussive neural injury Open
View article: Editorial: Acute and chronic effects of sub-concussion on brain function
Editorial: Acute and chronic effects of sub-concussion on brain function Open
EDITORIAL article Front. Neurol., 06 January 2023Sec. Neurotrauma Volume 13 - 2022 | https://doi.org/10.3389/fneur.2022.1121589
View article: Association of Frequent Sexual Choking/Strangulation With Neurophysiological Responses: A Pilot Resting-State fMRI Study
Association of Frequent Sexual Choking/Strangulation With Neurophysiological Responses: A Pilot Resting-State fMRI Study Open
Being choked or strangled during partnered sex is an emerging sexual behavior, prevalent among young adult women. The goal of this study was to test whether, and to what extent, frequently being choked or strangled during sex is associated…
View article: The association between contact sport exposure and cervical sensorimotor dysfunction: a scoping review of implications for future musculoskeletal injury risk
The association between contact sport exposure and cervical sensorimotor dysfunction: a scoping review of implications for future musculoskeletal injury risk Open
Background While morphological changes to the cervical spine have been observed for over 40 years in response to contact sport participation, little is known about the secondary effects of the cervical impairment on future musculoskeletal …
View article: Association Between Serum Neurofilament Light and Glial Fibrillary Acidic Protein Levels and Head Impact Burden in Women's Collegiate Water Polo
Association Between Serum Neurofilament Light and Glial Fibrillary Acidic Protein Levels and Head Impact Burden in Women's Collegiate Water Polo Open
Recent investigations have identified water polo athletes as at risk for concussions and repetitive subconcussive head impacts. Head impact exposure in collegiate varsity women's water polo, however, has not yet been longitudinally quantif…
View article: Drill Intensity and Head Impact Exposure in Adolescent Football
Drill Intensity and Head Impact Exposure in Adolescent Football Open
BACKGROUND AND OBJECTIVES The objective of this study was to examine head-impact exposure by intensity level and position group, and to test the hypothesis that there would be an increase in cumulative head-impact exposure between drill in…
View article: Effects of Physical Exertion on Early Changes in Blood-Based Brain Biomarkers: Implications for the Acute Point of Care Diagnosis of Concussion
Effects of Physical Exertion on Early Changes in Blood-Based Brain Biomarkers: Implications for the Acute Point of Care Diagnosis of Concussion Open
Blood-based brain biomarkers (BBM) such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have potential to aid in the diagnosis of concussion. Recently developed point-of-care test devices woul…
View article: Frequency, Method, Intensity, and Health Sequelae of Sexual Choking Among U.S. Undergraduate and Graduate Students
Frequency, Method, Intensity, and Health Sequelae of Sexual Choking Among U.S. Undergraduate and Graduate Students Open
View article: Titrating the Translational Relevance of a Low-Level Repetitive Head Impact Model
Titrating the Translational Relevance of a Low-Level Repetitive Head Impact Model Open
Recently, there has been increased attention in the scientific community to the phenomenon of sub-concussive impacts, those hits to the head that do not cause the signs and symptoms of a concussion. Some authors suggest that sub-concussive…
View article: Frequent and Recent Non-fatal Strangulation/Choking During Sex and Its Association With fMRI Activation During Working Memory Tasks
Frequent and Recent Non-fatal Strangulation/Choking During Sex and Its Association With fMRI Activation During Working Memory Tasks Open
Being strangled, or “choked,” by a sexual partner has emerged as a prevalent, often wanted and consensual sexual behavior among adolescent and young adult women, yet the neurological consequences of repeated exposure to this behavior are u…
View article: Return to Learn: Preferences of College Educators When Receiving Concussion Medical Notes
Return to Learn: Preferences of College Educators When Receiving Concussion Medical Notes Open
The aim of this work is to uncover the preferences and perspectives of college educators as they interpret medical documentation outlining medically requested return-to-learn (RTL) instructions. Participants were recruited from five colleg…
View article: A preliminary model of football-related neural stress that integrates metabolomics with transcriptomics and virtual reality
A preliminary model of football-related neural stress that integrates metabolomics with transcriptomics and virtual reality Open
View article: Association of Plasma Tau With Mortality and Long-term Neurocognitive Impairment in Survivors of Pediatric Cerebral Malaria and Severe Malarial Anemia
Association of Plasma Tau With Mortality and Long-term Neurocognitive Impairment in Survivors of Pediatric Cerebral Malaria and Severe Malarial Anemia Open
In this study, plasma tau, a marker of injury to neuronal axons, was elevated in children with CM or SMA and was associated with mortality and persistent NCI in children with CM younger than 5 years.
View article: Chronic elevation of serum S100B but not neurofilament-light due to frequent choking/strangulation during sex in young adult women
Chronic elevation of serum S100B but not neurofilament-light due to frequent choking/strangulation during sex in young adult women Open
Being choked/strangled during a partnered sex is an emerging sexual behavior, particularly prevalent among adolescent and young adult women, but the neurobiological impact of choking remains unknown. This case-control study aimed to test w…
View article: Integrating multi-omics with neuroimaging and behavior: A preliminary model of dysfunction in football athletes
Integrating multi-omics with neuroimaging and behavior: A preliminary model of dysfunction in football athletes Open
View article: Educator perspectives on concussion management in the college classroom: a grounded theory introduction to collegiate return-to-learn
Educator perspectives on concussion management in the college classroom: a grounded theory introduction to collegiate return-to-learn Open
Objectives To gather the perspectives of collegiate instructors regarding how concussion is managed within the college classroom. To introduce the themes surrounding collegiate return-to-learn (RTL) and the classroom management of students…
View article: Classification of Comprehensive Neuro-Ophthalmologic Measures of Postacute Concussion
Classification of Comprehensive Neuro-Ophthalmologic Measures of Postacute Concussion Open
In this study, ET measures of slowed visual reaction time had high classification accuracy for concussion. Accurate, objective measures of NO function have the potential to improve concussion recognition and reduce the disability associate…
View article: 87842 The Effects of Head Impact Exposure on Changes in Neurocognitive and Oculomotor Function Across a High School American Football Season: A Pilot Study
87842 The Effects of Head Impact Exposure on Changes in Neurocognitive and Oculomotor Function Across a High School American Football Season: A Pilot Study Open
IMPACT: This work reveals the influence of a season of American football-related head impact exposure on two functional outcome measures in a cohort of adolescent boys, shedding light on the chronic effects of 'subconcussive head impacts.'…