Keith Dombrowski
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View article: Time to Acute Treatment in Intracerebral Hemorrhage Lags Significantly Behind Ischemic Stroke: A Multicenter, Observational Retrospective Study
Time to Acute Treatment in Intracerebral Hemorrhage Lags Significantly Behind Ischemic Stroke: A Multicenter, Observational Retrospective Study Open
BACKGROUND: Time-to-treatment goals for acute ischemic stroke (AIS) have substantially improved outcomes, yet similar metrics have not been studied in patients with intracerebral hemorrhage (ICH), where mortality rates are much higher. MET…
View article: Multicenter comparison of antiplatelet treatment strategies for urgent/emergent neuroendovascular stenting
Multicenter comparison of antiplatelet treatment strategies for urgent/emergent neuroendovascular stenting Open
Background Emergent neuroendovascular stenting presents challenges for the utilization of antiplatelet agents. Methods This was a multicenter, retrospective cohort of patients who underwent emergent neuroendovascular stenting. The primary …
View article: Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors
Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors Open
Background: Andexanet alfa is a modified recombinant inactive factor Xa (FXa) designed to reverse FXa inhibitors. ANNEXA-4 (Andexanet Alfa, a Novel Antidote to the Anticoagulation Effects of Factor Xa Inhibitors) was a multicenter, prospec…
View article: Post-Transplant Lymphoproliferative Disorder: A Rare Case of CNS Involvement following Renal Transplant
Post-Transplant Lymphoproliferative Disorder: A Rare Case of CNS Involvement following Renal Transplant Open
Background: Post-transplant lymphoproliferative disorders (PTLD) are rare immunosuppression complications affecting 5% of transplant patients. Isolated central nervous system (CNS)-PTLD without nodal or extra-nodal organ involvement is rar…
View article: Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke
Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke Open
ClinicalTrials.gov Identifier: NCT02415400.
View article: Acute inflammatory demyelinating polyneuropathy or Guillain-Barré syndrome associated with COVID-19: a case report
Acute inflammatory demyelinating polyneuropathy or Guillain-Barré syndrome associated with COVID-19: a case report Open
Background Coronavirus disease 2019 (COVID-19) is a global pandemic. The disease, typically characterized by bilateral pulmonary infiltrates and profound elevation of inflammatory markers, can range in severity from mild or asymptomatic il…
View article: Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies
Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies Open
This review discusses cerebral venous thrombosis (CVT), including diagnosis and treatment strategies, a rare class of stroke that, if unrecognized or untreated, can have devastating effects. Thrombosis of one or many cerebral veins leads t…
View article: Stroke in Patients With Peripheral Artery Disease
Stroke in Patients With Peripheral Artery Disease Open
Background and Purpose— Predictors of stroke and transient ischemic attack (TIA) in patients with peripheral artery disease (PAD) are poorly understood. The primary aims of this analysis were to (1) determine the incidence of ischemic/hemo…
View article: Acute Respiratory Distress Syndrome Associated With Clopidogrel in a Young Male Patient
Acute Respiratory Distress Syndrome Associated With Clopidogrel in a Young Male Patient Open
Background: Clopidogrel is a commonly prescribed antiplatelet drug in patients with stents and histories of arterial vascular disease. It generally has a favorable side effect profile with increasing bleeding risk as the main concern as an…
View article: American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography
American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography Open
2.1 ^*Recording electrodes should be free of inherent noise and drift.They should not significantly attenuate signals between 0.5 and 70 Hz.Experimental evidence suggests that silver-silver chloride or gold disk electrodes held on by collo…
View article: American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography
American Clinical Neurophysiology Society Guideline 1: Minimum Technical Requirements for Performing Clinical Electroencephalography Open
Although no single best method exists for recording EEGs under all circumstances, the following standards are considered the minimum for the usual clinical recording of EEGs in all age groups except the very young (see also Guideline 5: Mi…
View article: Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research
Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research Open
The Critical Care EEG Monitoring Research Consortium database has been successfully developed and implemented with a dual role as a collaborative research platform and a clinical reporting tool. It is now available for public download to b…