Keith Feldman
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View article: Incidence of probiotic sepsis and morbidity risk in premature infants: a meta-analysis
Incidence of probiotic sepsis and morbidity risk in premature infants: a meta-analysis Open
Background For preterm infants, supplementation with probiotics improves rates of necrotizing enterocolitis (NEC) and other morbidities. Case reports of probiotic sepsis have prompted warnings from the American Academy of Pediatrics and th…
View article: Black community member perceptions and ethics recommendations on epigenomic research
Black community member perceptions and ethics recommendations on epigenomic research Open
View article: Elevated Ambient Temperature Associated With Reduced Infectious Disease Test Positivity Rates: Retrospective Observational Analysis of Statewide COVID-19 Testing and Weather Across California Counties
Elevated Ambient Temperature Associated With Reduced Infectious Disease Test Positivity Rates: Retrospective Observational Analysis of Statewide COVID-19 Testing and Weather Across California Counties Open
Background From medication usage to the time of day, a number of external factors are known to alter human body temperature (BT), even in the absence of underlying pathology. In select cases, clinical guidance already suggests the consider…
View article: Impacts of zero-fare transit policy on health and social determinants: protocol for a natural experiment study
Impacts of zero-fare transit policy on health and social determinants: protocol for a natural experiment study Open
Population-level efforts are needed to increase levels of physical activity and healthy eating to reduce and manage chronic diseases such as obesity, cardiovascular disease, and type 2 diabetes. Interventions to increase public transit use…
View article: Complex trait associations in rare diseases and impacts on Mendelian variant interpretation
Complex trait associations in rare diseases and impacts on Mendelian variant interpretation Open
Emerging evidence implicates common genetic variation - aggregated into polygenic scores (PGS) - in the onset and phenotypic presentation of rare diseases. Here, we comprehensively map individual polygenic liability for 1102 open-source PG…
View article: Utilization of geospatial distribution in the measurement of study cohort representativeness
Utilization of geospatial distribution in the measurement of study cohort representativeness Open
Together, these metrics provide a comprehensive spatial assessment of a study cohort with respect to a broader target population. Such an approach offers researchers a toolset by which to target expected generalization of results derived f…
View article: A Shadow over Palestine
A Shadow over Palestine Open
View article: Issue Information
Issue Information Open
Corporate Responsibility & ESG: ESG (Environmental, Social, Governance) is essential to Wiley's mission of unlocking human potential.For over two centuries, Wiley has a history of helping the world's researchers, learners, innovators, and …
View article: Clarification of adverse drug reactions by a pharmacovigilance team results in increased antibiotic re-prescribing at a freestanding United States children’s hospital
Clarification of adverse drug reactions by a pharmacovigilance team results in increased antibiotic re-prescribing at a freestanding United States children’s hospital Open
Documentation of adverse drug reactions (ADRs) is a key factor in guiding future prescribing. However, incomplete documentation is common and often fails to distinguish implicated drugs as true allergies. This in turn leads to unnecessary …
View article: Complex trait associations in rare diseases and impacts on Mendelian variant interpretation
Complex trait associations in rare diseases and impacts on Mendelian variant interpretation Open
Emerging evidence implicates common genetic variation – aggregated into polygenic scores (PGS) – impacting the onset and phenotypic presentation of rare diseases. In this study, we quantified individual polygenic liability for 1,151 previo…
View article: Issue Information
Issue Information Open
Cost-utility analysis of 4% tetrasodium ethylenediaminetetraacetic acid, taurolidine, and heparin lock to prevent central line-associated bloodstream infections in children with intestinal failure Comparison of direct effects of rice-thick…
View article: Representing Outcome-driven Higher-order Dependencies in Graphs of Disease Trajectories
Representing Outcome-driven Higher-order Dependencies in Graphs of Disease Trajectories Open
The widespread application of machine learning techniques to biomedical data has produced many new insights into disease progression and improving clinical care. Inspired by the flexibility and interpretability of graphs (networks), as wel…
View article: Issue Information
Issue Information Open
and Rest of World), €670 (Europe), £560 (UK
View article: Issue Information
Issue Information Open
and Rest of World), €670 (Europe), £560 (UK
View article: Issue Information
Issue Information Open
and Rest of World), €670 (Europe), £560 (UK
View article: Issue Information
Issue Information Open
and Rest of World), €670 (Europe), £560 (UK
View article: Characterization of a Vigorous sucking style in early infancy and its predictive value for weight gain and eating behaviors at 12 months
Characterization of a Vigorous sucking style in early infancy and its predictive value for weight gain and eating behaviors at 12 months Open
View article: Issue Information
Issue Information Open
Stress, anxiety, depression, and health-related quality of life in caregivers of children with intestinal failure receiving parenteral nutrition: A cross-sectional survey study Outcomes in preterm infants who received a lipid emulsion with…
View article: Prevalence of Parenteral Nutrition-Associated Liver Disease in Neonates With Congenital Heart Disease
Prevalence of Parenteral Nutrition-Associated Liver Disease in Neonates With Congenital Heart Disease Open
Objective: Infants receiving parenteral nutrition (PN) are at increased risk of PN associated liver disease (PNALD) which can manifest in hepatic fibrosis. While congenital heart disease (CHD) represents a risk factor for hepatic fibrosis,…
View article: Utility of the <sup>13</sup>C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children
Utility of the <sup>13</sup>C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children Open
The 13 C‐pantoprazole breath test (PAN‐BT) is a safe, noninvasive, in vivo CYP2C19 phenotyping probe for adults. Our objective was to evaluate PAN‐BT performance in children, with a focus on discriminating individuals who, according to gui…
View article: Will Apple devices’ passive atrial fibrillation detection prevent strokes? Estimating the proportion of high-risk actionable patients with real-world user data
Will Apple devices’ passive atrial fibrillation detection prevent strokes? Estimating the proportion of high-risk actionable patients with real-world user data Open
Objective Utilizing integrated electronic health record (EHR) and consumer-grade wearable device data, we sought to provide real-world estimates for the proportion of wearers that would likely benefit from anticoagulation if an atrial fibr…
View article: Identifying HbA1c trajectories and modifiable risk factors of trajectories in 5‐ to 9‐year‐olds with recent‐onset type 1 diabetes from the United States
Identifying HbA1c trajectories and modifiable risk factors of trajectories in 5‐ to 9‐year‐olds with recent‐onset type 1 diabetes from the United States Open
Objective To explore glycated haemoglobin (HbA1c) patterns in 5‐ to 9‐year‐olds in the recent‐onset period of type 1 diabetes and identify parent psychosocial factors that may predict children's HbA1c trajectory using a prospective, longit…
View article: Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia
Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia Open
View article: Examining Response to Negative Life Events Through Fitness Tracker Data
Examining Response to Negative Life Events Through Fitness Tracker Data Open
Negative life events, such as the death of a loved one, are an unavoidable part of life. These events can be overwhelmingly stressful and may lead to the development of mental health disorders. To mitigate these adverse developments, prior…
View article: Utilization of the Naranjo scale to evaluate adverse drug reactions at a free-standing children’s hospital
Utilization of the Naranjo scale to evaluate adverse drug reactions at a free-standing children’s hospital Open
The relationship between the Naranjo scaling system and pediatric adverse drug reactions (ADR) is poorly understood. We performed a retrospective review of 1,676 pediatric ADRs documented at our hospital from 2014–2018. We evaluated patien…
View article: Deviations from normal bedtimes are associated with short-term increases in resting heart rate
Deviations from normal bedtimes are associated with short-term increases in resting heart rate Open
View article: Unraveling Complexity about Childhood Obesity and Nutritional Interventions: Modeling Interactions Among Psychological Factors
Unraveling Complexity about Childhood Obesity and Nutritional Interventions: Modeling Interactions Among Psychological Factors Open
View article: Examining the weekend effect across ICU performance metrics
Examining the weekend effect across ICU performance metrics Open
This work reinforces the importance of accounting for differences in clinical factors as well as patient cohorts in studies investigating the weekend effect.
View article: #identity: Hashtagging Race, Gender, Sexuality, and Nation
#identity: Hashtagging Race, Gender, Sexuality, and Nation Open
"Since its launch in 2006, Twitter has served as a major platform for political performance, social justice activism, and large-scale public debates over race, ethnicity, gender, sexuality, and nationality. It has empowered minoritarian gr…
View article: Sustainable Publishing for Digital Scholarship in the Humanities
Sustainable Publishing for Digital Scholarship in the Humanities Open
This is a link to a webinar recording of a Charleston Conference webinar titled "Sustainable Publishing for Digital Scholarship in the Humanities," sponsored by University of Michigan Press and hosted by the Charleston Conference. It was o…