Keith Grimaldi
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View article: The Association of VDR, CYP2R1, and GC Gene Polymorphisms, Dietary Intake, and BMI in Regulating Vitamin D Status
The Association of VDR, CYP2R1, and GC Gene Polymorphisms, Dietary Intake, and BMI in Regulating Vitamin D Status Open
Vitamin D plays a crucial role in bone health and immune function, with serum 25(OH)D levels influenced by genetic, dietary, and metabolic factors. Background/Objectives: This study investigated the impact of VDR rs731236, CYP2R1 rs1074165…
View article: Additional file 1 of Development and validation of next generation sequencing based 35-gene hereditary cancer panel
Additional file 1 of Development and validation of next generation sequencing based 35-gene hereditary cancer panel Open
Additional file 1: Table S1. Known associations between genes in the 35-gene hereditary cancer panel and caner type. Table S2. Prenetics hereditary cancer panel reportable range. Table S3. Quality control metrics. Table S4. Exonic coverage…
View article: Precision Nutrition and the Microbiome Part II: Potential Opportunities and Pathways to Commercialisation
Precision Nutrition and the Microbiome Part II: Potential Opportunities and Pathways to Commercialisation Open
Modulation of the human gut microbiota through probiotics, prebiotics and dietary fibre are recognised strategies to improve health and prevent disease. Yet we are only beginning to understand the impact of these interventions on the gut m…
View article: Mediterranean Diet Adherence and Genetic Background Roles within a Web-Based Nutritional Intervention: The Food4Me Study
Mediterranean Diet Adherence and Genetic Background Roles within a Web-Based Nutritional Intervention: The Food4Me Study Open
Mediterranean Diet (MedDiet) adherence has been proven to produce numerous health benefits. In addition, nutrigenetic studies have explained some individual variations in the response to specific dietary patterns. The present research aime…
View article: Genome-Wide Association Studies Identify 15 Genetic Markers Associated with Marmite Taste Preference
Genome-Wide Association Studies Identify 15 Genetic Markers Associated with Marmite Taste Preference Open
Marmite is a popular food eaten around the world, to which individuals have commonly considered themselves either “lovers” or “haters”. We aimed to determine whether this food preference has a genetic basis.Weperformed a genome-wide associ…
View article: A response to letter to the editor: A genetic-based algorithm for personalized resistance training
A response to letter to the editor: A genetic-based algorithm for personalized resistance training Open
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Jones N, Kiely J, Suraci B, et al. A response to letter to the editor: A genetic-based algorithm for personalized resistance training. Biology of Sport. 2017…
View article: The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study
The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study Open
ClinicalTrials.gov NCT01530139.
View article: Weekday sunlight exposure, but not vitamin D intake, influences the association between vitamin D receptor genotype and circulating concentration 25‐hydroxyvitamin D in a pan‐European population: the Food4Me study
Weekday sunlight exposure, but not vitamin D intake, influences the association between vitamin D receptor genotype and circulating concentration 25‐hydroxyvitamin D in a pan‐European population: the Food4Me study Open
Scope Little is known about diet– and environment–gene interactions on 25‐hydroxyvitamin D (25(OH)D concentration. This cross‐sectional study aimed to investigate (i) predictors of 25(OH)D concentration and relationships with vitamin D gen…
View article: Effect of personalized nutrition on health-related behaviour change: evidence from the Food4me European randomized controlled trial
Effect of personalized nutrition on health-related behaviour change: evidence from the Food4me European randomized controlled trial Open
Among European adults, PN advice via internet-delivered intervention produced larger and more appropriate changes in dietary behaviour than a conventional approach.
View article: A genetic-based algorithm for personalized resistance-training
A genetic-based algorithm for personalized resistance-training Open
Association studies have identified dozens of genetic variants linked to training responses and sport-related traits. However, no intervention studies utilizing the idea of personalised training based on athlete's genetic profile have been…
View article: Physical activity attenuates the effect of the <scp><i>FTO</i></scp> genotype on obesity traits in European adults: The <scp>Food4Me</scp> study
Physical activity attenuates the effect of the <span><i>FTO</i></span> genotype on obesity traits in European adults: The <span>Food4Me</span> study Open
Objective To examine whether the effect of FTO loci on obesity‐related traits could be modified by physical activity (PA) levels in European adults. Methods Of 1,607 Food4Me participants randomized, 1,280 were genotyped for FTO (rs9939609)…
View article: The Ketogenic Diet and Sport
The Ketogenic Diet and Sport Open
The ketogenic diet (KD) is used widely as a weight loss strategy and, more rarely, as therapy for some diseases. In many sports, weight control is often necessary (boxing, weightlifting, wrestling, etc.), but the KD usually is not consider…
View article: Effects of n-3 Polyunsaturated Fatty Acids (ω-3) Supplementation on Some Cardiovascular Risk Factors with a Ketogenic Mediterranean Diet
Effects of n-3 Polyunsaturated Fatty Acids (ω-3) Supplementation on Some Cardiovascular Risk Factors with a Ketogenic Mediterranean Diet Open
Background: the ketogenic diet (KD) has become a widely used nutritional approach for weight loss. Some of the KD’s positive effects on metabolism and cardiovascular risk factors are similar to those seen after n-3 polyunsaturated fatty ac…
View article: The influence of MTHFR risk knowledge on changes in folate intake: results from the Food4Me study
The influence of MTHFR risk knowledge on changes in folate intake: results from the Food4Me study Open
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