Kelly A. Dyer
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View article: Comparative Genomics of the Testacea Group of <i>Drosophila</i> Reveals Introgression and Variation in Chromosome Size and Structure
Comparative Genomics of the Testacea Group of <i>Drosophila</i> Reveals Introgression and Variation in Chromosome Size and Structure Open
Comparative genomic analyses among closely related species provide an opportunity to assess their evolutionary history. The relatedness between species can depend on a variety of factors, including reproductive isolation, introgression, an…
View article: An experimental test of the evolutionary consequences of sympatry in <i>Drosophila subquinaria</i>
An experimental test of the evolutionary consequences of sympatry in <i>Drosophila subquinaria</i> Open
Prezygotic isolation is often stronger between sympatric as opposed to allopatric taxa, but the underlying cause can be difficult to infer from comparative studies alone. Experimental evolution, where evolutionary responses to treatments m…
View article: Investigating the phylogenetic history of toxin tolerance in mushroom‐feeding <i>Drosophila</i>
Investigating the phylogenetic history of toxin tolerance in mushroom‐feeding <i>Drosophila</i> Open
Understanding how and when key novel adaptations evolved is a central goal of evolutionary biology. Within the immigrans‐tripunctata radiation of Drosophila , many mushroom‐feeding species are tolerant of host toxins, such as cyclopeptides…
View article: Investigating the phylogenetic history of toxin tolerance in mushroom-feeding<i>Drosophila</i>
Investigating the phylogenetic history of toxin tolerance in mushroom-feeding<i>Drosophila</i> Open
Understanding how and when key novel adaptations evolved is a central goal of evolutionary biology. Within the immigrans-tripunctata radiation of Drosophila , many mushroom-feeding species are tolerant of host toxins, such as cyclopeptides…
View article: <i>Drosophila</i> Evolution over Space and Time (DEST): A New Population Genomics Resource
<i>Drosophila</i> Evolution over Space and Time (DEST): A New Population Genomics Resource Open
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome data sets from natural populations of this species have been published over the last years. A major challenge is the integ…
View article: Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Open
To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele freque…
View article: <i>Drosophila</i> Evolution over Space and Time (DEST) - A New Population Genomics Resource
<i>Drosophila</i> Evolution over Space and Time (DEST) - A New Population Genomics Resource Open
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last 20 years. A major challenge is the int…
View article: Fitness consequences of a non-recombining<i>sex-ratio</i>drive chromosome can explain its prevalence in the wild
Fitness consequences of a non-recombining<i>sex-ratio</i>drive chromosome can explain its prevalence in the wild Open
Understanding the pleiotropic consequences of gene drive systems on host fitness is essential to predict their spread through a host population. Here, we study sex-ratio (SR) X-chromosome drive in the fly Drosophila recens , where SR cause…
View article: Ongoing hybridization obscures phylogenetic relationships in the <i>Drosophila subquinaria</i> species complex
Ongoing hybridization obscures phylogenetic relationships in the <i>Drosophila subquinaria</i> species complex Open
Inferring evolutionary relationships among recently diverged lineages is necessary to understand how isolating barriers produce independent lineages. Here, we investigate the phylogenetic relationships between three incompletely isolated a…
View article: Supplementary material from "Fitness consequences of a non-recombining <i>sex-ratio</i> drive chromosome can explain its prevalence in the wild"
Supplementary material from "Fitness consequences of a non-recombining <i>sex-ratio</i> drive chromosome can explain its prevalence in the wild" Open
Understanding the pleiotropic consequences of gene drive systems on host fitness is essential to predict their spread through a host population. Here, we study sex-ratio (SR) X-chromosome drive in the fly Drosophila recens, where SR causes…
View article: A fast‐evolving X‐linked duplicate of <i>importin‐α2</i> is overexpressed in <i>sex‐ratio</i> drive in <i>Drosophila neotestacea</i>
A fast‐evolving X‐linked duplicate of <i>importin‐α2</i> is overexpressed in <i>sex‐ratio</i> drive in <i>Drosophila neotestacea</i> Open
Selfish genetic elements that manipulate gametogenesis to achieve a transmission advantage are known as meiotic drivers. Sex‐ratio X chromosomes (SR) are meiotic drivers that prevent the maturation of Y‐bearing sperm in male carriers to re…
View article: Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States
Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States Open
Our whole genome sequence (WGS) pipeline was assessed for accurate prediction of antimicrobial phenotypes. For 2316 invasive pneumococcal isolates recovered during 2015 we compared WGS pipeline data to broth dilution testing (BDT) for 18 a…
View article: Occasional recombination of a selfish X‐chromosome may permit its persistence at high frequencies in the wild
Occasional recombination of a selfish X‐chromosome may permit its persistence at high frequencies in the wild Open
The sex‐ratio X‐chromosome ( SR ) is a selfish chromosome that promotes its own transmission to the next generation by destroying Y‐bearing sperm in the testes of carrier males. In some natural populations of the fly D rosophila neotestace…
View article: Patterns of reproductive isolation in the<i>Drosophila subquinaria</i>complex: can reinforced premating isolation cascade to other species?
Patterns of reproductive isolation in the<i>Drosophila subquinaria</i>complex: can reinforced premating isolation cascade to other species? Open
The reinforcement of premating barriers due to reduced hybrid fitness in sympatry may cause secondary sexual isolation within a species as a by-product. Consistent with this, in the fly Drosophila subquinaria, females that are sympatric wi…
View article: Phylogenetic Patterns of Codon Evolution in the ACTIN-DEPOLYMERIZING FACTOR/COFILIN (ADF/CFL) Gene Family
Phylogenetic Patterns of Codon Evolution in the ACTIN-DEPOLYMERIZING FACTOR/COFILIN (ADF/CFL) Gene Family Open
The actin-depolymerizing factor/cofilin (ADF/CFL) gene family encodes a diverse group of relatively small proteins. Once known strictly as modulators of actin filament dynamics, recent research has demonstrated that these proteins are invo…
View article: Convergent evolution of strigolactone perception enabled host detection in parasitic plants
Convergent evolution of strigolactone perception enabled host detection in parasitic plants Open
How plant parasites evolved to find hosts The seeds of parasitic plants need to be able to sense their host's presence to germinate at the correct time and in the correct place. This is done through the detection of plant hormones, strigol…