Kelly X. Huang
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View article: Analysis of Craniofacial Microsomia and Facial Asymmetry: Approaches in Facial Feminization Surgery
Analysis of Craniofacial Microsomia and Facial Asymmetry: Approaches in Facial Feminization Surgery Open
Background Comprehensive facial analysis among transgender and gender-diverse (TGD) individuals undergoing facial feminization surgery (FFS) has created new opportunities to investigate facial asymmetry in adults. Although craniofacial mic…
View article: Surgical Strategies for Tumors of the Pancreas and Duodenum
Surgical Strategies for Tumors of the Pancreas and Duodenum Open
The recommended surgery for pancreatic tumors is dependent on the diagnosis. For pancreatic adenocarcinoma, duodenal, and ampullary adenocarcinoma, a Whipple pancreaticoduodenectomy with lymph node dissection is recommended. For small < 2 …
View article: Orai1 is Required for Osteogenic Differentiation on Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials
Orai1 is Required for Osteogenic Differentiation on Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials Open
The role of the extracellular matrix (ECM) in guiding cell fate has spurred the development of synthetic, ECM‐inspired regenerative biomaterials. We previously described a porous, open‐cell foam composed of nanoparticulate mineralized coll…
View article: Resorbable Poly-(D,L)-Lactide Anchorage of Nanoparticulate Mineralized Collagen Materials Maximizes <i>In Vivo</i> Skull Regeneration
Resorbable Poly-(D,L)-Lactide Anchorage of Nanoparticulate Mineralized Collagen Materials Maximizes <i>In Vivo</i> Skull Regeneration Open
Background A clinical demand exists for bone biomaterials that mirror tissue-specific extracellular matrix (ECM) properties and regulate progenitor cell fate. Nanoparticulate mineralized collagen glycosaminoglycan (MC-GAG) scaffolds have d…
View article: 125. Addressing Facial Asymmetry and Craniofacial Microsomia For Gender-affirming Reconstruction
125. Addressing Facial Asymmetry and Craniofacial Microsomia For Gender-affirming Reconstruction Open
View article: 40. Psychosocial Growth Chart for Children With Craniofacial Anomalies: A Prospective Longitudinal Study
40. Psychosocial Growth Chart for Children With Craniofacial Anomalies: A Prospective Longitudinal Study Open
View article: 155. Decellularized Adipose Matrices and Fat Grafting in Wound Healing Following Radiation-induced Fibrosis
155. Decellularized Adipose Matrices and Fat Grafting in Wound Healing Following Radiation-induced Fibrosis Open
View article: 51. Fixation of Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials With Poly(D,L-lactide) Implants Improves In Vivo Skull Regeneration
51. Fixation of Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials With Poly(D,L-lactide) Implants Improves In Vivo Skull Regeneration Open
View article: The Type I+ Forehead in Facial Feminization Surgery
The Type I+ Forehead in Facial Feminization Surgery Open
Background Feminizing fronto-orbital reconstruction involves one of four possibilities with the Ousterhout Type III anterior table frontal sinus osteotomy and setback performed in most patients while the Type I reduction recontouring is re…
View article: Estrogen hormone therapy stabilizes lateral hairline in transfeminine patients: Implications for facial feminization surgery
Estrogen hormone therapy stabilizes lateral hairline in transfeminine patients: Implications for facial feminization surgery Open
Although older age is a predictor of lateral hairline recession in TGNB AMAB individuals, lateral forehead length was also predicted to decrease by 0.07 cm with each year of feminizing hormone therapy in patients over 30 years of age.
View article: Correlating Material Properties to Osteoprotegerin Expression on Nanoparticulate Mineralized Collagen Glycosaminoglycan Scaffolds
Correlating Material Properties to Osteoprotegerin Expression on Nanoparticulate Mineralized Collagen Glycosaminoglycan Scaffolds Open
Precision material design directed by cell biological processes represents a frontier in developing clinically translatable regenerative technologies. While understanding cell‐material interactions on multipotent progenitor cells yields in…
View article: Medicaid coverage for gender‐affirming surgery: A state‐by‐state review
Medicaid coverage for gender‐affirming surgery: A state‐by‐state review Open
Objective To systematically review Medicaid policies state‐by‐state for gender‐affirming surgery coverage. Data Sources and Study Setting Primary data were collected for each US state utilizing the LexisNexis legal database, state legislat…
View article: Ethnic variation in lower face anthropometry on facial computed tomography scans for patients seeking facial feminization surgery
Ethnic variation in lower face anthropometry on facial computed tomography scans for patients seeking facial feminization surgery Open
Specific target areas of FFS should be carefully considered to account for possible baseline ethnic differences. Relative facial proportions may also be a more salient surgical planning tool in transgender and gender nonbinary patients rat…
View article: 91. Patient-Reported Anxiety, Depression, And Emotional Support: Key Predictors Of Postoperative Psychosocial Outcomes In Facial Feminization Surgery
91. Patient-Reported Anxiety, Depression, And Emotional Support: Key Predictors Of Postoperative Psychosocial Outcomes In Facial Feminization Surgery Open
Purpose: Individuals experiencing gender dysphoria often confront heightened levels of misunderstanding, persecution, and societal stigmatization. Particularly among transgender and gender non-conforming (TGNC) individuals assigned male at…
View article: Long-term outcomes of sphincter pharyngoplasty in patients with cleft palate
Long-term outcomes of sphincter pharyngoplasty in patients with cleft palate Open
View article: Indole-Based and Cyclopentenylindole-Based Analogues Containing Fluorine Group as Potential 18F-Labeled Positron Emission Tomography (PET) G-Protein Coupled Receptor 44 (GPR44) Tracers
Indole-Based and Cyclopentenylindole-Based Analogues Containing Fluorine Group as Potential 18F-Labeled Positron Emission Tomography (PET) G-Protein Coupled Receptor 44 (GPR44) Tracers Open
Recently, growing evidence of the relationship between G-protein coupled receptor 44 (GPR44) and the inflammation-cancer system has garnered tremendous interest, while the exact role of GPR44 has not been fully elucidated. Currently, there…
View article: Physician behaviors associated with increased physician and nurse communication during bedside interdisciplinary rounds
Physician behaviors associated with increased physician and nurse communication during bedside interdisciplinary rounds Open
Background Effective team communication during interdisciplinary rounds (IDRs) is a hallmark of safe, efficient, patient‐centered care. However, there is limited understanding of optimal IDR structures and procedures. Objective This study …
View article: An enhanced recovery after surgery protocol for facial feminization surgery reduces perioperative opioid usage, pain, and hospital stay
An enhanced recovery after surgery protocol for facial feminization surgery reduces perioperative opioid usage, pain, and hospital stay Open
The current work details an ERAS protocol for facial feminization surgery that reduces perioperative opioid consumption, patient-reported pain scores, and hospital stays.
View article: Design, Synthesis, Computational and Biological Evaluation of Novel Structure Fragments Based on Lithocholic Acid (LCA)
Design, Synthesis, Computational and Biological Evaluation of Novel Structure Fragments Based on Lithocholic Acid (LCA) Open
The regulation of bile acid pathways has become a particularly promising therapeutic strategy for a variety of metabolic disorders, cancers, and diseases. However, the hydrophobicity of bile acids has been an obstacle to clinical efficacy …
View article: Convergence of Calcium Channel Regulation and Mechanotransduction in Skeletal Regenerative Biomaterial Design
Convergence of Calcium Channel Regulation and Mechanotransduction in Skeletal Regenerative Biomaterial Design Open
Cells are known to perceive their microenvironment through extracellular and intracellular mechanical signals. Upon sensing mechanical stimuli, cells can initiate various downstream signaling pathways that are vital to regulating prolifera…
View article: 165. Nanoparticulate Mineralized Collagen Scaffolds Activate The Integrin B1 Signaling Pathway
165. Nanoparticulate Mineralized Collagen Scaffolds Activate The Integrin B1 Signaling Pathway Open
PURPOSE: The capabilities of the extracellular matrix (ECM) to instruct progenitor cell fate determination has resulted in a significant interest in developing ECM-inspired materials for regenerative applications. We previously reported on…
View article: 106. Increased Length of Gender-Affirming Hormone Therapy is Associated with Greater Facial Fat Pad Volume in Transfeminine Patients
106. Increased Length of Gender-Affirming Hormone Therapy is Associated with Greater Facial Fat Pad Volume in Transfeminine Patients Open
PURPOSE: Patterns in facial soft tissue distribution and volumes are known to vary based on the assigned gender at birth of the individual. In patients who are transgender and assigned male at birth, augmentation of facial volumes via non-…
View article: 22. The Role of Orai1 in Osteogenic Differentiation Induced by Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials
22. The Role of Orai1 in Osteogenic Differentiation Induced by Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials Open
PURPOSE: Development of synthetic regenerative materials inspired by the extracellular matrix (ECM) has been a topic of significant interest due to the known properties of the ECM to direct cell fate determination via tunable material comp…
View article: 192. Dynamic Changes In Temporospatial Phosphate Equilibrium By Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials Induces Osteogenesis Via Pit-1 And Pit-2
192. Dynamic Changes In Temporospatial Phosphate Equilibrium By Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials Induces Osteogenesis Via Pit-1 And Pit-2 Open
PURPOSE: Fabrication of biomaterials that emulate properties of tissue-specific extracellular matrix (ECM) and consequently regulate progenitor cell fate are of particular interest in the development of a "materials-only" regenerative appl…
View article: Association of Patient-Reported Anxiety and Pain After Alveolar Bone Grafting
Association of Patient-Reported Anxiety and Pain After Alveolar Bone Grafting Open
Objective To evaluate the role of psychosocial well-being on perioperative pain and opioid use among patients with cleft lip and palate (CLP) undergoing alveolar bone grafting (ABG). Design Retrospective review. Setting Tertiary level cran…
View article: Modulating Temporospatial Phosphate Equilibrium by Nanoparticulate Mineralized Collagen Materials Induces Osteogenesis via PiT‐1 and PiT‐2
Modulating Temporospatial Phosphate Equilibrium by Nanoparticulate Mineralized Collagen Materials Induces Osteogenesis via PiT‐1 and PiT‐2 Open
The temporospatial equilibrium of phosphate contributes to physiological bone development and fracture healing, yet optimal control of phosphate content has not been explored in skeletal regenerative materials. Nanoparticulate mineralized …
View article: Talimogene Laherparepvec (T-VEC): A Review of the Recent Advances in Cancer Therapy
Talimogene Laherparepvec (T-VEC): A Review of the Recent Advances in Cancer Therapy Open
The landscape of melanoma treatment has undergone a dramatic revolution in the past decade. The use of oncolytic viruses (OVs) represents a novel therapeutic approach that can selectively infect and lyse tumor cells and induce local and sy…
View article: Osteoprotegerin-eluting nanoparticulate mineralized collagen scaffolds improve skull regeneration
Osteoprotegerin-eluting nanoparticulate mineralized collagen scaffolds improve skull regeneration Open
View article: QS77. Implementation of an Enhanced Recovery After Surgery Protocol for Facial Feminization Surgery Reduces Pain, Opioid Usage, and Length of Hospital Stay
QS77. Implementation of an Enhanced Recovery After Surgery Protocol for Facial Feminization Surgery Reduces Pain, Opioid Usage, and Length of Hospital Stay Open
Purpose: Patients undergoing gender-affirming surgeries represent a potentially vulnerable cohort for prolonged opioid use. In addition to gender dysphoria, transgender patients are frequently diagnosed with anxiety or depression, known ri…
View article: 33. Uncoupling of Osteogenic and Osteoclastogenic Differentiation on Nanoparticulate Mineralized Collagen Scaffolds Through Physisorption of Osteoprotegerin
33. Uncoupling of Osteogenic and Osteoclastogenic Differentiation on Nanoparticulate Mineralized Collagen Scaffolds Through Physisorption of Osteoprotegerin Open
Purpose: Osteoprotegerin (OPG) plays an important role in bone metabolism by functioning as a decoy receptor for receptor activator of nuclear factor kB (RANK) ligand (RANKL) in the RANK/RANKL/OPG axis, resulting in the inhibition of osteo…