Kelsey Caetano-Anollés
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View article: Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration Open
View article: Accelerating Biomedical Discoveries in Aging and Neurodegeneration Through Transformative Neuropathology
Accelerating Biomedical Discoveries in Aging and Neurodegeneration Through Transformative Neuropathology Open
Transformative neuropathology is redefining human brain research by integrating foundational descriptive pathology with advanced methodologies to drive discoveries that inform diagnostics, therapeutics, and disease prevention. These approa…
View article: Tracing the birth and intrinsic disorder of loops and domains in protein evolution
Tracing the birth and intrinsic disorder of loops and domains in protein evolution Open
View article: On Protein Loops, Prior Molecular States and Common Ancestors of Life
On Protein Loops, Prior Molecular States and Common Ancestors of Life Open
View article: Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease
Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease Open
Importance Factors associated with clinical heterogeneity in Alzheimer disease (AD) lay along a continuum hypothesized to associate with tangle distribution and are relevant for understanding glial activation considerations in therapeutic …
View article: Seasonal effects decouple SARS-CoV-2 haplotypes worldwide
Seasonal effects decouple SARS-CoV-2 haplotypes worldwide Open
Background: Variants of concern (VOCs) have been replacing each other during the still rampant COVID-19 pandemic. As a result, SARS-CoV-2 populations have evolved increasingly intricate constellations of mutations that often enhance transm…
View article: Clinicoradiologic Correlates of Corticolimbic Index (CLix) and Glial Activation Differences Among Neuropathologic Subtypes of Alzheimer's Disease: A Retrospective Study
Clinicoradiologic Correlates of Corticolimbic Index (CLix) and Glial Activation Differences Among Neuropathologic Subtypes of Alzheimer's Disease: A Retrospective Study Open
View article: Recruitment: A Problem of Entangled Temporal Parts
Recruitment: A Problem of Entangled Temporal Parts Open
Recruitment is a pervasive activity of life that is at the center of novelty generation and persistence. Without recruitment, novelties cannot spread and biological systems cannot maintain identity through time. Here we explore the problem…
View article: Author Correction: Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Author Correction: Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle Open
View article: Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle Open
Background Africa is an important watershed in the genetic history of domestic cattle, as two lineages of modern cattle, Bos taurus and B. indicus , form distinct admixed cattle populations. Despite the predominant B. indicus nuclear ances…
View article: Additional file 2 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Additional file 2 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle Open
Additional file 2: Table S2. Summary of mitochondrial genome sequences.
View article: The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality
The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality Open
View article: Additional file 4 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Additional file 4 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle Open
Additional file 4: Dataset S1. Bos taurus and Bos indicus cattle mitochondrial genome sequences generated from 216 whole-genome sequencing data.
View article: The seasonal behaviour of COVID-19 and its galectin-like culprit of the viral spike
The seasonal behaviour of COVID-19 and its galectin-like culprit of the viral spike Open
View article: Additional file 1 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Additional file 1 of Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle Open
Additional file 1: Table S1. Summary of genome re-sequencing using whole-genome sequencing data.
View article: Emergence of Hierarchical Modularity in Evolving Networks Uncovered by Phylogenomic Analysis
Emergence of Hierarchical Modularity in Evolving Networks Uncovered by Phylogenomic Analysis Open
Networks describe how parts associate with each other to form integrated systems which often have modular and hierarchical structure. In biology, network growth involves two processes, one that unifies and the other that diversifies. Here,…
View article: Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits
Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits Open
African indigenous cattle breeds have been reared within the continent for millennia. Due to the harsh tropical environmental conditions (e.g. sever disease and parasite prevalence, high temperature, feed and water scarcity) where they evo…
View article: Microbial community and functions associated with digestion of algal polysaccharides in the visceral tract of Haliotis discus hannai: Insights from metagenome and metatranscriptome analysis
Microbial community and functions associated with digestion of algal polysaccharides in the visceral tract of Haliotis discus hannai: Insights from metagenome and metatranscriptome analysis Open
Haliotis discus hannai, a species of Pacific abalone, is a highly valuable food source throughout Northeast Asia. As H. discus hannai primarily feed on brown algae and largely extract their energy from algal polysaccharides, understanding …
View article: Origin and spread of Thoroughbred racehorses inferred from complete mitochondrial genome sequences: Phylogenomic and Bayesian coalescent perspectives
Origin and spread of Thoroughbred racehorses inferred from complete mitochondrial genome sequences: Phylogenomic and Bayesian coalescent perspectives Open
The Thoroughbred horse breed was developed primarily for racing, and has a significant contribution to the qualitative improvement of many other horse breeds. Despite the importance of Thoroughbred racehorses in historical, cultural, and e…
View article: Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes
Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes Open
View article: Artificial selection increased body weight but induced increase of runs of homozygosity in Hanwoo cattle
Artificial selection increased body weight but induced increase of runs of homozygosity in Hanwoo cattle Open
Artificial selection has been demonstrated to have a rapid and significant effect on the phenotype and genome of an organism. However, most previous studies on artificial selection have focused solely on genomic sequences modified by artif…
View article: Additional file 3: of Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes
Additional file 3: of Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes Open
FASTA sequences for scaffolds which have locations with depthâ >â 10Ă . (XLSX 9907 kb)
View article: Additional file 4: of Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes
Additional file 4: of Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes Open
Protein sequences which have locations with depthâ >â 10Ă . (XLSX 101 kb)
View article: Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits
Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits Open
African indigenous cattle breeds have been reared within the continent for millennia. Due to the harsh tropical environmental conditions (e.g. sever disease and parasite prevalence, high temperature, feed and water scarcity) where they evo…
View article: Structures in 4D: a 'double tale' of biological accretion
Structures in 4D: a 'double tale' of biological accretion Open
View article: Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits
Exploring the genomes of East African Indicine cattle breeds reveals signature of selection for tropical environmental adaptation traits Open
African indigenous cattle breeds have been reared within the continent for millennia. Due to the harsh tropical environmental conditions (e.g. sever disease and parasite prevalence, high temperature, feed and water scarcity) where they evo…
View article: Genome sequence of the Japanese oak silk moth, Antheraea yamamai: the first draft genome in the family Saturniidae
Genome sequence of the Japanese oak silk moth, Antheraea yamamai: the first draft genome in the family Saturniidae Open
Here we present the genome sequence of A. yamamai, the first genome sequence of the wild silk moth. These results provide valuable genomic information, which will help enrich our understanding of the molecular mechanisms relating to not on…
View article: Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance
Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance Open
As African indigenous cattle evolved in a hot tropical climate, they have developed an inherent thermotolerance; survival mechanisms include a light‐colored and shiny coat, increased sweating, and cellular and molecular mechanisms to cope …
View article: Genome sequence of pacific abalone (Haliotis discus hannai): the first draft genome in family Haliotidae
Genome sequence of pacific abalone (Haliotis discus hannai): the first draft genome in family Haliotidae Open
Abalones are large marine snails in the family Haliotidae and the genus Haliotis belonging to the class Gastropoda of the phylum Mollusca. The family Haliotidae contains only one genus, Haliotis, and this single genus is known to contain s…
View article: Whole genome scan reveals the genetic signature of African Ankole cattle breed and potential for higher quality beef
Whole genome scan reveals the genetic signature of African Ankole cattle breed and potential for higher quality beef Open