Kelsie J. Anson
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View article: Zn<sup>2+</sup>influx activates ERK and Akt signaling pathways through a common mechanism
Zn<sup>2+</sup>influx activates ERK and Akt signaling pathways through a common mechanism Open
Zinc (Zn 2+ ) is an essential metal in biology and its bioavailability is highly regulated. Many cell types exhibit fluctuations in Zn 2+ that appear to play an important role in cellular function. However, the detailed molecular mechanism…
View article: Factors That Improve RT-QuIC Detection of Prion Seeding Activity
Factors That Improve RT-QuIC Detection of Prion Seeding Activity Open
Rapid and sensitive detection of prions is important in managing prion diseases. The real-time quaking-induced conversion (RT-QuIC) assay for prion seeding activity has been applied to many prion diseases and provides for specific antemort…
View article: Prion Protein Prolines 102 and 105 and the Surrounding Lysine Cluster Impede Amyloid Formation
Prion Protein Prolines 102 and 105 and the Surrounding Lysine Cluster Impede Amyloid Formation Open