Kemala Isnainiasih Mantilidewi
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View article: Comparison of Chondroitin Sulfate-E Expression in Benign and Malignant Epithelial Type Ovarian Tumors
Comparison of Chondroitin Sulfate-E Expression in Benign and Malignant Epithelial Type Ovarian Tumors Open
Objective: Ovarian cancer is the fifth leading cause of cancer-related death in women, due to late diagnosis and limited screening methods. Chondroitin Sulfate-E (CS-E) has shown potential as biomarkers. This study aims to evaluate CS-E ex…
View article: HALP and SII: Innovative Biomarkers for Diagnosing Ovarian Cancer in Both Epithelial and Non-Epithelial Subtypes
HALP and SII: Innovative Biomarkers for Diagnosing Ovarian Cancer in Both Epithelial and Non-Epithelial Subtypes Open
Objective: To evaluate the diagnostic utility of PHAL (Platelet, Hemoglobin, Albumin, and Lymphocyte), SII (Systemic Immune Inflammation Index), and SIRI (Systemic Inflammatory Response Index) for both epithelial and non-epithelial ovarian…
View article: Management paradigm for ovarian neuroendocrine carcinoma: a systematic review
Management paradigm for ovarian neuroendocrine carcinoma: a systematic review Open
Introduction Neuroendocrine neoplasms (NENs) of the female genital tract are rare, comprising only 1–2% of gynecologic tumors, with ovarian neuroendocrine carcinoma (O-NEC) accounting for less than 1% of all ovarian cancers. Despite its ra…
View article: Integration of Portable PCR and a Lateral Flow Assay for the Rapid Detection of HPV Type 16
Integration of Portable PCR and a Lateral Flow Assay for the Rapid Detection of HPV Type 16 Open
This simplified and cost-effective method provides a user-friendly alternative to traditional electrophoresis, making it suitable for resource-limited settings. Further large-scale clinical validation is warranted, including cost analyses …
View article: Systemic Inflammatory Biomarkers as a Predictive Markers for Ovarian Cancer
Systemic Inflammatory Biomarkers as a Predictive Markers for Ovarian Cancer Open
Systemic inflammatory biomarkers, particularly SII may aid in the predictive markers of early ovarian with diagnostic values nearly as good as CA125 (sensitivity 71.64% vs 75.97%). These biomarkers can serve as complementary predictive mar…
View article: Postmenopausal endometriosis
Postmenopausal endometriosis Open
A postmenopausal woman, in her 60s, married with no history of pregnancy, presented to our facility with an abdominal mass of 2 months duration that progressively increased in size. Physical examination revealed a mobile abdominal cystic m…
View article: A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights
A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights Open
Double primer cancer of the ovary and thyroid, which is a clear cell ovarian carcinoma metachronous with papillary thyroid carcinoma, is possible.
View article: Wound Dehiscence Following Obstetrics and Gynecology Surgeries: An Observational Study at a Tertiary Hospital in Bandung
Wound Dehiscence Following Obstetrics and Gynecology Surgeries: An Observational Study at a Tertiary Hospital in Bandung Open
Introduction: Wound dehiscence is a severe postoperative complication that disrupts an abdominal wound closure which can be caused by endogenous or exogenous flora that infect a surgical wound. Many factors are responsible for surgical sit…
View article: Nomogram development for predicting ovarian tumor malignancy using inflammatory biomarker and CA-125
Nomogram development for predicting ovarian tumor malignancy using inflammatory biomarker and CA-125 Open
Global challenges in ovarian cancer underscore the need for cost-effective screening. This study aims to assess the role of pretreatment Neutrophil-to-Lymphocyte Ratio (NLR), Lymphocyte-to-Monocyte-Ratio (LMR), Platelet-to-Lymphocyte Ratio…
View article: Association between CD103 and E-cadherin Immunoexpression with Pelvic Lymph Node Metastasis in Cervical Squamous Cell Carcinoma
Association between CD103 and E-cadherin Immunoexpression with Pelvic Lymph Node Metastasis in Cervical Squamous Cell Carcinoma Open
Background Lymph node (LN) metastasis is a poor prognostic factor for cervical squamous cell carcinoma (SCC). One important predictor of LN metastasis is lymphocytic inflammatory reaction, which may be indicated by infiltration of CD103 + …
View article: Allogeneic human umbilical cord mesenchymal stem cell secretome effect on apoptosis of HeLa cells
Allogeneic human umbilical cord mesenchymal stem cell secretome effect on apoptosis of HeLa cells Open
Introduction: Cervical cancer treatment typically involves surgery, chemotherapy, and radiotherapy. However, exploring novel treatment approaches is crucial. Stem cell secretome therapy provides new insights as an additional option in the …
View article: Results Comparison of Cervical Cancer Early Detection Using Cerviray with VIA Test
Results Comparison of Cervical Cancer Early Detection Using Cerviray with VIA Test Open
Objectives This study investigates the performance of Cerviray A.I. and evaluation of Cerviray A.I. by an expert, an artificial intelligence (AI) technology for diagnosing cervical cancer, aiming to compare its sensitivity, specificity, po…
View article: Characteristics of Endometrioma Recurrence Patients
Characteristics of Endometrioma Recurrence Patients Open
Objective: To identify the characteristics of endometrioma recurrence cases. Method: This study was a descriptive retrospective, using secondary data taken from all medical records of Clinic Aster and Medical Records Installation in Dr. Ha…
View article: Characteristics of Endometrioma Recurrence Patients
Characteristics of Endometrioma Recurrence Patients Open
Objective: To identify the characteristics of endometrioma recurrence cases. Method: This study was a descriptive retrospective, using secondary data taken from all medical records of Clinic Aster and Medical Records Installation in Dr. Ha…
View article: Characteristics of Referral Patients with Gestational Trophoblastic Neoplasia in Dr. Hasan Sadikin General Hospital Bandung
Characteristics of Referral Patients with Gestational Trophoblastic Neoplasia in Dr. Hasan Sadikin General Hospital Bandung Open
Background: : Gestational trophoblastic disease (GTD) is a heterogeneous group of lesions caused by abnormal trophoblast proliferation and the malignant form is called gestational trophoblastic neoplasia (GTN). Dr. Hasan Sadikin General Ho…
View article: Clinicopathological Characteristics of Cervical Carcinoma with Pelvic Lymph Node Metastases in Dr. Hasan Sadikin General Hospital, Bandung 2013-2021
Clinicopathological Characteristics of Cervical Carcinoma with Pelvic Lymph Node Metastases in Dr. Hasan Sadikin General Hospital, Bandung 2013-2021 Open
Background: Carcinoma of the cervix is the most common gynecological malignancy, which ranks first among carcinomas in Indonesia. Lymph node metastasis is a risk of recurrence, affecting survival and therapy. The purpose of this study was …
View article: Comparison of Extravillous Intermediate Trophoblast Invasion Depth and Distribution Pattern Between Placenta Accreta and Non-Accreta
Comparison of Extravillous Intermediate Trophoblast Invasion Depth and Distribution Pattern Between Placenta Accreta and Non-Accreta Open
BACKGROUND Placenta accreta spectrum (PAS) is a complex obstetric complication that poses a major risk for life-threatening hemorrhage. The pathogenesis of PAS is known to be related to placentogenesis, trophoblastic cells invasion, and pr…
View article: Laparoscopic Cystectomy of Endometrioma Outcomes on Follicle Stimulating Hormone and Anti-Müllerian Hormone Levels as Predictors of the Ovarian Reserve
Laparoscopic Cystectomy of Endometrioma Outcomes on Follicle Stimulating Hormone and Anti-Müllerian Hormone Levels as Predictors of the Ovarian Reserve Open
Objectives: This study aimed to examine the effect of a laparoscopic cystectomy on ovarian reserve assessed by measuring the levels of serum follicle stimulating hormone (FSH) and anti-Müllerian hormone (AMH). Materials and Methods: This p…
View article: Risk Factors That Correlate with Resistance to First-Line Chemotherapy on High-risk Gestational Trophoblastic Neoplasia
Risk Factors That Correlate with Resistance to First-Line Chemotherapy on High-risk Gestational Trophoblastic Neoplasia Open
BACKGROUND: Gestational trophoblastic neoplasia (GTN) is a condition arising from abnormal proliferation of the trophoblastic cells. GTN incidence in Indonesia, precisely in Hasan Sadikin General Hospital, as many as 730 cases are reported…
View article: Myxoid Liposarcoma of the Vulva: A Rare Malignancy Mimicking Benign Vulvar Mass
Myxoid Liposarcoma of the Vulva: A Rare Malignancy Mimicking Benign Vulvar Mass Open
BACKGROUND Liposarcoma of the vulva is an exceptionally rare malignant tumor. Clinically, vulvar liposarcoma often mimics benign lesions, thus misdiagnosis is common. Herein, we present a case of myxoid liposarcoma of the vulva. To the bes…
View article: Bacteriological Profile and Antibiotic Sensitivity Pattern of Surgical Site Infection Following Gynecologic Oncology Surgery at Hasan Sadikin General Hospital
Bacteriological Profile and Antibiotic Sensitivity Pattern of Surgical Site Infection Following Gynecologic Oncology Surgery at Hasan Sadikin General Hospital Open
Introduction: Surgical site infection (SSI) is the most common complication of gynecologic oncology surgeries. Understanding the characteristics, bacteriological profile, and antibiotic sensitivity pattern of SSI patients can help guide pa…
View article: Cervical Pre-cancerous Lesion Detection: Development of Smartphone-Based VIA Application Using Artificial Intelligence
Cervical Pre-cancerous Lesion Detection: Development of Smartphone-Based VIA Application Using Artificial Intelligence Open
ObjectiveAbout 90% of deaths caused by cervical cancer in 2020 occurred in low-and middle-income countries, due to limited access to screening programs. Visual inspection of cervix after acetic acid application (VIA) has been considered an…
View article: A Rare Case of Squamous Cell Carcinoma Arising in Mature Cystic Teratoma
A Rare Case of Squamous Cell Carcinoma Arising in Mature Cystic Teratoma Open
BACKGROUND: Mature cystic teratoma (MCT) is a common benign adnexal tumor contributing to about 20% of all ovarian tumors, and it may occur in 10–20% of women during their lifetime. Although the nature of MCT of the ovary is benign, about …
View article: Natural History of Paclitaxel-associated Acute Pain Syndrome: A Case Report of Rare Side Effect of Paclitaxel
Natural History of Paclitaxel-associated Acute Pain Syndrome: A Case Report of Rare Side Effect of Paclitaxel Open
BACKGROUND: One of the harshest side effects following anticancer agent treatments is chemotherapy-induced neuropathic pain. After surgical staging, chemotherapy combination of paclitaxel carboplatin could be a choice of therapy for Stage …
View article: Relationship of Histopathological Representation of Excessive Proliferation of Trophoblast Cells with the Possibility of Malignant Events After Complete Hydatidiform Mole
Relationship of Histopathological Representation of Excessive Proliferation of Trophoblast Cells with the Possibility of Malignant Events After Complete Hydatidiform Mole Open
The conclusion of the study was there is a significant correlation between marked trophoblastic cell proliferation with the incidence of post-complete hydatidiform mole malignancy.
View article: A Rare Case of Early Transformation of Gestational Trophoblastic Neoplasia Following Molar Pregnancy
A Rare Case of Early Transformation of Gestational Trophoblastic Neoplasia Following Molar Pregnancy Open
BACKGROUND Gestational trophoblastic disease (GTD) encompasses a group of disorders that arise from abnormal growth of trophoblastic tissue. The spectrum of GTD includes 2 major groups: benign and malignant. The benign form is a hydatidifo…
View article: The Impact of Nifedipine on Maternal and Fetal Blood Stream on the Threat of Preterm Labor: an Experimental Study
The Impact of Nifedipine on Maternal and Fetal Blood Stream on the Threat of Preterm Labor: an Experimental Study Open
Background: Preterm birth is a significant cause of perinatal morbidity and mortality and that becomes a major challenge in perinatal health care. Various pharmacological agents that inhibit uterine contractions are used in clinical practi…