Ken‐ichi Ogura
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View article: <scp>IRE</scp>‐1/<scp>XBP</scp>‐1 pathway of the unfolded protein response is required for properly localizing neuronal <scp>UNC</scp>‐6/Netrin for axon guidance in <i>C. elegans</i>
<span>IRE</span>‐1/<span>XBP</span>‐1 pathway of the unfolded protein response is required for properly localizing neuronal <span>UNC</span>‐6/Netrin for axon guidance in <i>C. elegans</i> Open
During developing nervous system, neurons project axons to their targets precisely. In this process, axon guidance molecules provide positional information to the axons. Therefore, the spatially and temporally controlled localization of th…
View article: A Seven-Transmembrane Receptor That Mediates Avoidance Response to Dihydrocaffeic Acid, a Water-Soluble Repellent in<i>Caenorhabditis elegans</i>
A Seven-Transmembrane Receptor That Mediates Avoidance Response to Dihydrocaffeic Acid, a Water-Soluble Repellent in<i>Caenorhabditis elegans</i> Open
The ability to detect harmful chemicals rapidly is essential for the survival of all animals. In Caenorhabditis elegans ( C. elegans ), repellents trigger an avoidance response, causing animals to move away from repellents. Dihydrocaffeic …
View article: Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in<i>Caenorhabditis elegans</i>
Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in<i>Caenorhabditis elegans</i> Open
UNC-51 is a serine/threonine protein kinase conserved from yeast to humans. The yeast homolog Atg1 regulates autophagy (catabolic membrane trafficking) required for surviving starvation. In C. elegans, UNC-51 regulates the axon guidance of…
View article: Genes Required for Cellular UNC-6/Netrin Localization in <i>Caenorhabditis elegans</i>
Genes Required for Cellular UNC-6/Netrin Localization in <i>Caenorhabditis elegans</i> Open
UNC-6/Netrin is an evolutionarily conserved, secretory axon guidance molecule. In Caenorhabditis elegans, UNC-6 provides positional information to the axons of developing neurons, probably by establishing a concentration gradient from the …
View article: Roles of adenine anchoring and ion pairing at the coenzyme B<sub>12</sub>‐binding site in diol dehydratase catalysis
Roles of adenine anchoring and ion pairing at the coenzyme B<sub>12</sub>‐binding site in diol dehydratase catalysis Open
The X‐ray structure of the diol dehydratase–adeninylpentylcobalamin complex revealed that the adenine moiety of adenosylcobalamin is anchored in the adenine‐binding pocket of the enzyme by hydrogen bonding of N3 with the side chain OH grou…
View article: Survey of Catalytic Residues and Essential Roles of Glutamate-α170 and Aspartate-α335 in Coenzyme B12-dependent Diol Dehydratase
Survey of Catalytic Residues and Essential Roles of Glutamate-α170 and Aspartate-α335 in Coenzyme B12-dependent Diol Dehydratase Open
The importance of each active-site residue in adenosylcobalamin-dependent diol dehydratase of Klebsiella oxytoca was estimated using mutant enzymes in which one of the residues interacting with substrate and/or K(+) was mutated to Ala or a…
View article: Translational control of maternal glp-1 mRNA by POS-1 and its interacting protein SPN-4 in Caenorhabditis elegans
Translational control of maternal glp-1 mRNA by POS-1 and its interacting protein SPN-4 in Caenorhabditis elegans Open
The translation of maternal glp-1 mRNAs is regulated temporally and spatially in C. elegans embryos. The 3′ UTR (untranslated region) of the maternal glp-1 mRNA is important for both kinds of regulation. The spatial control region is requi…
View article: Abundance and Productivity of Microphytobenthos on a Rocky Shore in Southern Hokkaido
Abundance and Productivity of Microphytobenthos on a Rocky Shore in Southern Hokkaido Open