Ken Zhu
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View article: Influence of T Cell-Mediated Immune Surveillance on Somatic Mutation Occurrences in Melanoma
Influence of T Cell-Mediated Immune Surveillance on Somatic Mutation Occurrences in Melanoma Open
Background Neoantigens are presented on the cancer cell surface by peptide-restricted human leukocyte antigen (HLA) proteins and can subsequently activate cognate T cells. It has been hypothesized that the observed somatic mutations in tum…