Explanipedia

Unplanned coronary artery bypass grafting during elective aortic root surgery increases peri-operative morbidity and mortality Open

Sankrit R. Kapoor, Nimesh D. Desai, Daniel D. Bazianos, Chase R. Brown, Waseem Lutfi , et al. · 2025

Surgical Repair of Massive Ascending Aortic Pseudoaneurysm Open

Daniel D. Bazianos, Chia-Yi Chin, Kendall M. Lawrence · 2025

This surgical approach may be considered by surgical teams for management of high-risk reoperative aortic surgery.

Effect of Transcatheter Aortic Valve Replacement Program Ratings on Case Selection Open

Yousuf Shah, Lauren A. Eberly, Dharam J. Kumbhani, Mohamad Alkhouli, Suzanne J. Baron , et al. · 2025

Since 2020, there has been a substantial decline in the number of high-risk patients receiving TAVR across the United States, driven predominantly by hospitals that received lower USNWR TAVR ratings. This is likely, in part, driven by risk…

Cardiac valve prosthesis choice for left-sided infective endocarditis in Medicare patients Open

Waseem Lutfi, Ziwei Pan, Madison A. Grasty, Neha Goel, Michael A. Catalano , et al. · 2025

Aortic Valve–Sparing Root Operation in Patients With Marfan and Loeys-Dietz Syndrome Open

Murat Yıldız, Victoria Werdecker, Maria Nucera, Selim Mosbahi, Nicholas Goel , et al. · 2025

VSRR shows excellent midterm outcomes in patients with MFS and LDS. There are no outcome differences between patients with MFS and patients with LDS. The use of a Valsalva graft may be considered to reduce aortic reintervention rates in pa…

Postinfarction Left Ventricular Inferior Wall Aneurysm With Contained Rupture and Tamponade Physiology Open

David F. Painter, Varun Bhasin, Rohan Savoor, Ray Hu, Alvaro A. Ordoñez , et al. · 2025

Management of the dissected aortic root in young patients: A propensity score-matched analysis of mechanical versus bioprosthetic aortic root replacement Open

Michael A. Catalano, Omar Toubat, Lauren Gillinov, Kendall M. Lawrence, Yu Zhao , et al. · 2025

There is no survival advantage of mech-Bentall in ATAAD in young patients at 10 years, and it is associated with a significantly higher rate of morbid complications. When the aortic valve cannot be spared, bio-Bentall should be considered …

First reported surgical explantation of infected thoracic branched endograft requiring complex arch and descending thoracic aortic repair Open

Michael A. Catalano, Chia-Yi Chin, Nimesh D. Desai, Kendall M. Lawrence · 2025

We present a 51-year-old woman with thoracic aortitis and rapidly enlarging descending thoracic aortic aneurysm in the setting of Clostridium septicum bacteraemia. After antibiotic treatment, she underwent left carotid–subclavian transposi…

Advances and Innovation in Acute Type a Aortic Dissection Open

Madison A. Grasty, Kendall M. Lawrence · 2024

The prompt and appropriate management of acute type A aortic dissections is imperative for patient survival. Advances in medical technology have broadened the adjuncts available to treat the spectrum of pathology within this population. Th…

Deployment of a novel hybrid stent for open repair of acute DeBakey type I aortic dissection with malperfusion Open

John J. Kelly, Joshua C. Grimm, Kendall M. Lawrence, Michael Ibrahim, Lourdes F.S. Al Ghofaily , et al. · 2024

The AMDS Hybrid Prosthesis is a novel hybrid device for the treatment of acute DeBakey I aortic dissection in patients without an intimal tear in the arch. Central Picture Legend:The AMDS Hybrid Prosthesis is deployed antegrade during circ…

The AMDS Stent Reduces Postoperative Distal Anastomotic New Re-Entry (DANE) Tears, But Will It Reduce the Need for Late Aortic Reintervention? Open

Kendall M. Lawrence, Nimesh D. Desai · 2024

Contemporary outcomes of open repair of acute complicated type B aortic dissection Open

Christopher Lau, Giovanni Soletti, Kendall M. Lawrence, Mohamed Rahouma, Erin Iannacone , et al. · 2023

Mitral Valve Repair Is Effective When Performed With Valve-Sparing Aortic Root Replacement Open

Kendall M. Lawrence, Joseph E. Bavaria, John J. Kelly, Amit Iyengar, Brittany J. Cannon , et al. · 2023

Results of a Multimodal Approach for the Launch of a Ross Program Open

Michael E. Ibrahim, Kendall M. Lawrence, Joseph E. Bavaria, Joshua C. Grimm, Michael Acker , et al. · 2022

We demonstrate that with multidisciplinary education and extensive hands-on surgical preparation under proctored supervision, a Ross program can be initiated safely with excellent short-term results and perioperative risk that mimics that …

Balancing quality and quaternary care imperative using a high-risk case review committee in adults Open

Michael Ibrahim, Andrew Acker, Steve Weiss, Kendall M. Lawrence, Stephanie Ottemiller , et al. · 2022

OBJECTIVES Quaternary care centres have an imperative to serve as hospitals of last resort and must also meet professional quality targets. We developed a high-risk committee (HRC) to evaluate cases meeting pre-defined predicted risk cut-o…

With increasing data, can guidelines continue to overlook the Ross in adults? Open

Kendall M. Lawrence, Vasiliki Courelli, Karissa Tauber, Michael Ibrahim · 2022

Journal Article With increasing data, can guidelines continue to overlook the Ross in adults? Get access Kendall M Lawrence, Kendall M Lawrence Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA, USA Search fo…

Chronic hypoxemia induces mitochondrial respiratory complex gene expression in the fetal sheep brain Open

James K. Moon, Kendall M. Lawrence, Mallory L. Hunt, Marcus G. Davey, Alan W. Flake , et al. · 2022

Table of contents Open

Edward Buratto, Igor E. Konstantinov, Anusha Jegatheeswaran, Neil D. Patel, Connie Friedman , et al. · 2021

Contrast‐enhanced ultrasound imaging can be used to evaluate fetal cerebral perfusion: potential implications for fetal surgery Open

Kendall M. Lawrence, Barbara E. Coons, Anush Sridharan, Avery C. Rossidis, Marcus G. Davey , et al. · 2021

Background Fetal surgery is increasingly performed to correct congenital defects. Currently, fetal brain perfusion cannot be assessed intra-operatively. The purpose of this study was to determine if contrast-enhanced ultrasound (CEUS) coul…

Contrast-enhanced Ultrasound Imaging Can be Used to Evaluate Fetal Cerebral Perfusion: Potential Implications for Fetal Surgery Open

Kendall M. Lawrence, Barbara E. Coons, Anush Sridha, Avery C. Rossidis, Marcus G. Davey , et al. · 2020

Background : Fetal surgery is increasingly performed to correct congenital defects . Currently, fetal brain perfusion cannot be assessed intra-operatively. The purpose of this study was to determine if contrast-enhanced ultrasound (CEUS) c…

The EXTrauterine Environment for Neonatal Development Supports Normal Intestinal Maturation and Development Open

Heron D. Baumgarten, Christina M. Wright, Avery C. Rossidis, Kendall M. Lawrence, Aimee G. Kim , et al. · 2020

Prenatal hypoxemia alters microglial morphology in fetal sheep Open

Kendall M. Lawrence, Patrick E. McGovern, Ali Y. Mejaddam, Avery C. Rossidis, Heron D. Baumgarten , et al. · 2019

Magnet ingestion leading to intestinal fistulae, phytobezoar formation, and small bowel obstruction Open

Kendall M. Lawrence, Matthew K. Iyer, Prerana Baranwal, Aliza Solomon, Nitsana Spigland · 2019

Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep Open

Kendall M. Lawrence, Patrick E. McGovern, Ali Y. Mejaddam, Avery C. Rossidis, Heron D. Baumgarten , et al. · 2019

Fetal hypoxemia causes abnormal myocardial development in a preterm ex utero fetal ovine model Open

Kendall M. Lawrence, Samson Hennessy-Strahs, Patrick E. McGovern, Ali Y. Mejaddam, Avery C. Rossidis , et al. · 2018

In utero hypoxia is a major cause of neonatal morbidity and mortality and predisposes to adult cardiovascular disease. No therapies exist to correct fetal hypoxia. In a new ex utero fetal support system, we tested the hypothesis that hypox…

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