Kathryn A. Ellis
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View article: Balance on the Brain: Facilitators and barriers of intervention implementation
Balance on the Brain: Facilitators and barriers of intervention implementation Open
Introduction: Balance on the Brain is a balance-focused multi-modal community-based exercise intervention aimed at reducing falls and improving health outcomes for people living with Mild Cognitive Impairment (MCI). This study completed an…
View article: Development of a Pilot Specialist Dementia Nurse at a Tertiary Victorian Hospital
Development of a Pilot Specialist Dementia Nurse at a Tertiary Victorian Hospital Open
The pathway to a diagnosis of dementia and post-diagnostic support can be complicated for people living with dementia and their support networks, leading to delays in care. This paper describes the development and subsequent pilot of a spe…
View article: Associations between physical activity, sedentary behaviour and cognitive domain performance of people living with mild cognitive impairment in the community
Associations between physical activity, sedentary behaviour and cognitive domain performance of people living with mild cognitive impairment in the community Open
Introduction Physical activity is known to positively influence cognitive performance. For adults with mild cognitive impairment (MCI), the relationship between physical activity levels and cognitive performance is unknown. This cross‐sect…
View article: 3T sodium-MRI as predictor of neurocognition in nondemented older adults: a cross sectional study
3T sodium-MRI as predictor of neurocognition in nondemented older adults: a cross sectional study Open
Dementia is a burgeoning global problem. Novel magnetic resonance imaging (MRI) metrics beyond volumetry may bring new insight and aid clinical trial evaluation of interventions early in the Alzheimer’s disease course to complement existin…
View article: The dopaminergic system and human spatial working memory: a behavioural, eletrophysiological and cerebral blood flow investigation
The dopaminergic system and human spatial working memory: a behavioural, eletrophysiological and cerebral blood flow investigation Open
Dopamine appears to play a critical role in regulating spatial working memory (SWM) in non-human primates, and SWM deficits are observed in patients with Parkinson's disease and schizophrenia. Unfortunately, the current experimental litera…
View article: EXCEL ‐ EXercise for Cognitive hEaLth: A pilot 12‐week online home‐based physical activity program for middle‐aged and older adults with cognitive and mental health concerns.
EXCEL ‐ EXercise for Cognitive hEaLth: A pilot 12‐week online home‐based physical activity program for middle‐aged and older adults with cognitive and mental health concerns. Open
Background Physical inactivity significantly increases dementia risk (DR). For middle‐aged and older adults with co‐occurring cognitive concerns/impairment and mental health symptoms, DR increases further. Clinical trials indicate lower ad…
View article: Later life Body composition and Alzheimer’s disease
Later life Body composition and Alzheimer’s disease Open
Background Mid‐life obesity is linked with increased risk for late‐life dementia, however relationships between later‐life body composition and dementia are less clear. Method Using a combined cohort from two major observational studies (A…
View article: Designing EXercise for Cognitive hEalth in depression and anxiety: the EXCEL study
Designing EXercise for Cognitive hEalth in depression and anxiety: the EXCEL study Open
Background Physical inactivity significantly contributes to chronic disease burden, including increasing dementia risk. Physical activity (PA) can benefit cognitive health for groups at high‐risk of dementia, such as people experiencing co…
View article: P56: Exercising your worries away – what do older adults think about physical activity and technology interventions to reduce anxiety
P56: Exercising your worries away – what do older adults think about physical activity and technology interventions to reduce anxiety Open
Objective: Older adults have low levels of mental health literacy relating to anxiety which may contribute to delaying or not seeking help. Lifestyle interventions, including physical activity (PA), have increasing evidence supporting thei…
View article: The potential of physical activity and technology interventions to reduce anxiety in older adults
The potential of physical activity and technology interventions to reduce anxiety in older adults Open
Background: Older adults have low levels of mental health literacy relating to anxiety, which may explain why they delay or do not seek help. Emerging evidence supports effectiveness of lifestyle interventions, including physical activity …
View article: <i>Lrrn1</i>Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti
<i>Lrrn1</i>Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti Open
One of the most striking aspects of the sensory epithelium of the mammalian cochlea, the organ of Corti (OC), is the presence of precise boundaries between sensory and nonsensory cells at its medial and lateral edges. A particular example …
View article: Physical Activity for Cognitive Health: A Model for Intervention Design for People Experiencing Cognitive Concerns and Symptoms of Depression or Anxiety
Physical Activity for Cognitive Health: A Model for Intervention Design for People Experiencing Cognitive Concerns and Symptoms of Depression or Anxiety Open
Background: People experiencing cognitive concerns and symptoms of depression or anxiety are at risk for Alzheimer’s disease and dementia. We know physical activity can benefit cognition but understanding how to best support engagement is …
View article: Effects of a Multi-component, Resistance-Based Exercise Program Combined with Additional Lean Red Meat on Health-Related Quality of Life in Older Adults: Secondary Analysis of a 6-Month Randomized Controlled Trial
Effects of a Multi-component, Resistance-Based Exercise Program Combined with Additional Lean Red Meat on Health-Related Quality of Life in Older Adults: Secondary Analysis of a 6-Month Randomized Controlled Trial Open
A multi-component resistance-based training program performed with and without the provision of lean red meat in line with current Australian dietary guidelines on each of the three training days, did not improve HR-QoL in healthy communit…
View article: Linking self-perceived cognitive functioning questionnaires using item response theory: The subjective cognitive decline initiative.
Linking self-perceived cognitive functioning questionnaires using item response theory: The subjective cognitive decline initiative. Open
This was the first study to calibrate self-perceived cognitive functioning data of geographically diverse older adults. The resulting item scores are on the same metric, facilitating joint or pooled analyses across international studies. R…
View article: Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit
Adrenaline auto-injector injuries: Practical considerations in emergency management in a tertiary hand surgery unit Open
Adrenaline auto-injectors are the first line treatment for anaphylaxis in the community setting. Both anaphylaxis and auto-injector carriage are increasing in prevalence. Adrenaline auto-injector injuries are common and most often involve …
View article: Examination of the Feasibility, Acceptability, and Efficacy of the Online Personalised Training in Memory Strategies for Everyday Program for Older Adults: Single-Arm Pre-Post Trial
Examination of the Feasibility, Acceptability, and Efficacy of the Online Personalised Training in Memory Strategies for Everyday Program for Older Adults: Single-Arm Pre-Post Trial Open
Background Memory strategy training for older adults helps maintain and improve cognitive health but is traditionally offered face-to-face, which is resource intensive, limits accessibility, and is challenging during a pandemic. Web-based …
View article: Daily emotion regulation and emotional well-being: A replication and extension in Egypt
Daily emotion regulation and emotional well-being: A replication and extension in Egypt Open
Emotion regulation (ER) strategies have been linked to emotional well-being. However, most studies on this topic have been conducted on Western samples. Furthermore, related studies that have been conducted with non-Western samples have ex…
View article: Examination of the Feasibility, Acceptability, and Efficacy of the Online Personalised Training in Memory Strategies for Everyday Program for Older Adults: Single-Arm Pre-Post Trial (Preprint)
Examination of the Feasibility, Acceptability, and Efficacy of the Online Personalised Training in Memory Strategies for Everyday Program for Older Adults: Single-Arm Pre-Post Trial (Preprint) Open
BACKGROUND Memory strategy training for older adults helps maintain and improve cognitive health but is traditionally offered face-to-face, which is resource intensive, limits accessibility, and is challenging during a pandemic. Web-based…
View article: Changing Care: Applying the Transtheoretical Model of Change to Embed Equity, Diversity, and Inclusion in Long-Term Care Research in Canada
Changing Care: Applying the Transtheoretical Model of Change to Embed Equity, Diversity, and Inclusion in Long-Term Care Research in Canada Open
Healthcare policy reform is evident when considering the past, present and future of long-term care (LTC) in Canada. Some of the most pressing issues facing the LTC sector include the changing demographic composition in Canadian LTC homes,…
View article: Balance on the Brain: a randomised controlled trial evaluating the effect of a multimodal exercise programme on physical performance, falls, quality of life and cognition for people with mild cognitive impairment—study protocol
Balance on the Brain: a randomised controlled trial evaluating the effect of a multimodal exercise programme on physical performance, falls, quality of life and cognition for people with mild cognitive impairment—study protocol Open
Introduction Exercise and physical activity have been shown to improve cognition for people living with mild cognitive impairment (MCI). There is strong evidence for the benefits of aerobic exercise and medium evidence for participating in…
View article: The Support Person's Preferences and Perspectives of Physical Activity Programs for Older Adults With Cognitive Impairment
The Support Person's Preferences and Perspectives of Physical Activity Programs for Older Adults With Cognitive Impairment Open
Objectives: Physical activity (PA) is beneficial for older adults' cognition. There is limited research investigating perspectives of support persons (SPs) of next-of-kins (NOKs) with cognitive impairment. This exploratory study aimed to i…
View article: Ethnic Differences in Barriers and Enablers to Physical Activity Among Older Adults
Ethnic Differences in Barriers and Enablers to Physical Activity Among Older Adults Open
Despite its well-known health benefits, most older adults do not commit to undertaking sufficient physical activity (PA). In this study we aimed to examine the perceived benefits of and barriers and enablers to PA from the perspectives of …
View article: Dementia knowledge and associated factors among older Chinese adults: a cross-national comparison between Melbourne and Beijing
Dementia knowledge and associated factors among older Chinese adults: a cross-national comparison between Melbourne and Beijing Open
Older Chinese adults living in Melbourne and Beijing share similar levels of dementia knowledge, but factors associated with their knowledge are different. These findings will inform the development of culturally and socially appropriate d…
View article: Fifteen Years of the Australian Imaging, Biomarkers and Lifestyle (AIBL) Study: Progress and Observations from 2,359 Older Adults Spanning the Spectrum from Cognitive Normality to Alzheimer’s Disease
Fifteen Years of the Australian Imaging, Biomarkers and Lifestyle (AIBL) Study: Progress and Observations from 2,359 Older Adults Spanning the Spectrum from Cognitive Normality to Alzheimer’s Disease Open
Background: The Australian Imaging, Biomarkers and Lifestyle (AIBL) Study commenced in 2006 as a prospective study of 1,112 individuals (768 cognitively normal (CN), 133 with mild cognitive impairment (MCI), and 211 with Alzheimer’s diseas…
View article: Online Personalised Training in Memory Strategies for Everyday (OPTIMiSE) Program for Older Adults with Cognitive Concerns: Pilot Study Protocol
Online Personalised Training in Memory Strategies for Everyday (OPTIMiSE) Program for Older Adults with Cognitive Concerns: Pilot Study Protocol Open
Memory interventions for older adults with cognitive concerns result in improved memory performance and maintenance of cognitive health. These programs are typically delivered face-to-face, which is resource intensive and creates access ba…
View article: Deferiprone to delay dementia (the 3D trial)
Deferiprone to delay dementia (the 3D trial) Open
Background Potential therapeutic targets for Alzheimer’s disease (AD) outside of β‐amyloid are of increased interest. Brain iron has been reported to predict accelerated AD progression when measured using fluid biomarkers (CSF ferritin), q…
View article: Dementia knowledge among older Chinese adults: A cross‐national comparison between Melbourne and Beijing
Dementia knowledge among older Chinese adults: A cross‐national comparison between Melbourne and Beijing Open
Background Improving dementia knowledge among older populations has the potential to reduce risk factors or enable early diagnosis and timely treatment. This study compared dementia knowledge between older Chinese adults in Melbourne, Aust…