Explanipedia

125 Contactless Assessment of Vital Signs Using Remote Photoplethysmography in the Emergency Department Open

R.P. Kin Lam, Ryuhei So, M. Kow, Po Yee Mia Leung, KH Cheung , et al. · 2025

Outcome of Rotation Flap Combined with Incisional Negative Pressure Wound Therapy for Plantar Diabetic Foot Ulcers Open

Jiajun Feng, Coeway Boulder Thng, Jason Wong, Quah Mei Fern Alison, Nicole Tao Ying Lim , et al. · 2025

Background Diabetic foot ulcers (DFUs) affect approximately 20% of diabetic patients and pose significant risks, especially for plantar wounds that bear weight. Conventional treatments often have suboptimal results, necessitating the explo…

Mesenchymal Stem Cell Exosome and Fibrin Sealant Composite Enhances Rabbit Anterior Cruciate Ligament Repair Open

Keng Lin Wong, K. Teo, Gin Way Law, Shipin Zhang, Tianqi Wang , et al. · 2025

Background: The anterior cruciate ligament (ACL) fails to heal after rupture, leading to joint instability and an increased risk of osteoarthritis. Mesenchymal stem/stromal cell (MSC) exosomes have reported wide-ranging therapeutic efficac…

Pathological Site Pain During Injections as a Predictive Sign for Clinical Response in Autologous Protein Solution and Hyaluronic Acid Injections for Knee Osteoarthritis Open

Edmund Jia Xi Zhang, Craigven Hao Sheng Sim, Zachariah Gene Wing Ow, Erina Lie, Krishmen Rasu , et al. · 2024

Level III.

Polymer‐MOF Network Enabling Ultrathin Coating for Post‐Combustion Carbon Capture Open

Shuting Fan, Canzeng Liang, Fan Feng, Keng Lin Wong, Kaiyu Wang , et al. · 2024

Permeance‐selectivity trade‐off and high temperature resilience are key challenges in development of membranes for post‐combustion carbon capture. While mixed matrix membranes (MMMs) consisting of polymers and metal–organic frameworks (MOF…

Arthroscopic Cartilage Repair of the Patella With Minced Cartilage and Collagen Membrane Scaffold With Bone Marrow Aspirate Concentrate Open

Edmund Jia Xi Zhang, Zachariah Gene Wing Ow, Erina Lie, Ian Dominic Dhanaraj, Keng Lin Wong · 2024

The single-staged repair technique of patellofemoral cartilage lesions has previously been described, with the utility of a bilayer scaffold and minced cartilage via an open mini-arthrotomy, showing great clinical efficacy. We describe a p…

Addressing the Peri‐Wound Intact Skin of Hard‐To‐Heal Diabetic Foot Ulcers With Topical Red Deer Conditioned Media (PTT‐6<sup>TM</sup>) Skin Conditioner: A Case Series on Clinical Efficacy Open

Kimberley Leow, Leon Timothy Charles Alvis, Bernd Yuen, Lei Cheng, Shiqi Chiam , et al. · 2024

Background and Aim The healing of diabetic foot ulcers (DFUs) can be hindered by the susceptibility of the surrounding intact skin to pro‐inflammatory proteases. A conditioned media, known as PTT‐6 TM , derived from mesenchymal stem cells …

LIPO-AMIC Technique Description: Autologous Matrix Induced–Chondrogenesis With Microfragmented Adipose Tissue Graft Open

Pedro Debieux, G G Ribeiro, Keng Lin Wong, Moisés Cohen, Camila Cohen Kaleka · 2024

Cartilage injuries have historically been challenging to manage, but recent advancements have rapidly expanded treatment options. The incorporation of mesenchymal stem cell sources, such as bone marrow or adipose tissue, has improved repai…

Impact of Centrifugation Parameters on Platelet-Rich Plasma Injection for Patella Tendinopathy: A Systematic Review and Meta-Analysis Open

E Zhang, Vincentius Edward Lie, Keng Lin Wong · 2024

Patellar tendinopathy (PT) is a chronic, degenerative form of tendinitis commonly affecting young, active individuals. Numerous nonsurgical treatments exist, of which platelet-rich plasma (PRP) is a frontrunner. However, heterogeneity amon…

Exploring the potential of mesenchymal stem/stromal cell-derived extracellular vesicles as cell-free therapy for osteoarthritis: a narrative review Open

Kazunori Shimomura, Keng Lin Wong, Samundeeswari Saseendar, Sathish Muthu, Sebastian Concaro , et al. · 2024

Introduction: Mesenchymal stem/stromal cell (MSC)-based therapies in cartilage repair and osteoarthritis (OA) treatment have gained attention. Recently, there has been increasing evidence to suggest that MSCs secrete a wide range of trophi…

Corrigendum to ‘Noninferiority meta-analysis of autologous vs allogeneic osteochondral transplantation for the treatment of osteochondral defects of the knee confounded by defect size differences’ [J Cartil Joint Preserv 3 (2023) 100130] Open

Dexter Seow, Jin Hean Koh, Hannah Li Xin Cheang, Gin Way Law, Glenys Poon , et al. · 2024

The authors regret that there was an error in the affiliation list. The correct affiliations are shown above. The authors would like to apologize for any inconvenience caused. Noninferiority meta-analysis of autologous vs allogeneic osteoc…

Assessing acellular scaffold viability with T2-weighted relaxation time value imaging: imaging variables and early clinical associations at 6 months following patellofemoral cartilage repair Open

Zachariah Gene Wing Ow, Dean Wang, Edmund Jia Xi Zhang, Hamid Rahmatullah Bin Abd Razak, Steven Bak Siew Wong , et al. · 2024

This study aims to describe novel magnetic resonance imaging (MRI) imaging characteristics using T2-weighted relaxation time values (T2RVs) for evaluating acellular graft status following cartilage repair, addressing the limitations identi…

Acellular scaffolds, cellular therapy and next generation approaches for knee cartilage repair Open

Pedro Debieux, Enzo Salviato Mameri, Giovanna Medina, Keng Lin Wong, Camila Cohen Keleka · 2024

Introduction: Full-thickness knee cartilage defects are a potential source of significant morbidity for patients and incur an increased risk for early degenerative joint disease. Recent decades have seen several advancements in the field o…

Single-Stage Arthroscopic Cartilage Repair With Chondrectomy and Implantation of a Templated Membrane Collagen Scaffold With Bone Marrow Aspirate Concentrate Augmentation (AMIC Plus) Open

Zachariah Gene Wing Ow, Keng Lin Wong · 2023

Small extracellular vesicles from mesenchymal stromal cells: the next therapeutic paradigm for musculoskeletal disorders Open

Kristeen Ye Wen Teo, Rachel Tan, Keng Lin Wong, Hwee Weng Dennis Hey, James Hoi Po Hui , et al. · 2023

Noninferiority meta-analysis of autologous vs allogeneic osteochondral transplantation for the treatment of osteochondral defects of the knee confounded by defect size differences Open

Dexter Seow, Jin Hean Koh, Hannah Li Xin Cheang, Gin Way Law, Glenys Poon , et al. · 2023

Background: Autologous and allogeneic osteochondral transplantations are widely employed for knee osteochondral defects (OCDs). However, there has been a lack of consensus on the efficacy of autografts vs allografts. Objectives: To evaluat…

Similar short-term results between scaffold implanted mesenchymal stem cells vs acellular scaffolds with concentrated bone marrow aspirate augmentation for the repair of chondral defects of the knee: evidence from a meta-analysis Open

Zachariah Gene Wing Ow, Katelyn Kaye-Ling Lim, Shant Qinxiang Sin, Hannah Li Xin Cheang, Dean Wang , et al. · 2023

Background: Scaffold-implanted mesenchymal stem cells (MSCs) are gaining popularity for the treatment of cartilage defects. However, there is little evidence comparing its efficacy against the currently well-established technique of utiliz…

Radiographic Outcomes Following the Suture Fixation of Mid-pole Patellar Fractures Open

Bing Howe Lee, Michael Shen Xuanrong, Colin Wang Tzong-Yee, Huang Yilun, Keng Lin Wong , et al. · 2021

Are primary care referrals to the paediatric orthopaedic speciality clinic always clinically indicated? Open

Nazrul Nashi, Selena Xueli Choo, Chintan Doshi, Keng Lin Wong, Kean Seng Andrew Lim · 2021

Biomaterials for meniscus and cartilage in knee surgery: state of the art Open

Louis Kluyskens, Pedro Debieux, Keng Lin Wong, Aaron J. Krych, Daniël B.F. Saris · 2021

SARS-CoV-2 not detected in pus from forearm abscess in a COVID-19-infected patient Open

Aprine Tan, Keng Lin Wong, Hamid Rahmatullah Bin Abd Razak, Biauw-Chi Ong, Merng Koon Wong · 2021

Dear Sir, COVID-19 is transmitted mainly via respiratory droplets, and diagnosis is typically confirmed with polymerase chain reaction (PCR) tests of nasopharyngeal swabs.[1] So far, COVID-19 has been found in faecal, blood and cerebrospin…

The Painful Anterior Apprehension Test – An Indication of Occult Shoulder Instability Open

Yau Hong Ng, Gin Way Law, Zhaowen Dennis Ng, Jun Tan, Keng Lin Wong , et al. · 2020

Background To evaluate the clinical relevance of the painful anterior apprehension test in shoulder instability.MethodsWe performed a retrospective study of 155 patients that underwent arthroscopic anterior Bankart repair between 2014–2016…

Cervical Spine Fracture after a Bone Cracking Traditional (Tui Na) Massage Open

Glenys Poon, Keng Lin Wong, Haobin Chen, Sandip Singh Saggi, Maksim Lai , et al. · 2020

Cervical Spine Fracture after a Bone Cracking Traditional (Tui Na) MassageDear Editor, "Tui Na" (推拿) or traditional chinese medicine (TCM) massage is an alternative medicine therapy practised in many Chinese communities for the management …

Cervical Spine Fracture after a Bone Cracking Traditional (Tui Na) Massage. Open

Glenys Poon, Keng Lin Wong, Haobin Chen, Sandip Singh Saggi, Maksim Lai , et al. · 2020

Cardiothoracic surgery in the midst of a pandemic: Operative outcomes and maintaining a coronavirus disease 2019 (COVID-19)–free environment Open

Damian Balmforth, Martin T. Yates, Kelvin Lau, Azhar Hussain, Ana López-Marco , et al. · 2020

The Painful Anterior Apprehension Test – An Indication Of Occult Shoulder Instability Open

Yau Hong Ng, Gin Way Law, Zhaowen Dennis Ng, Jun Hao Tan, Keng Lin Wong , et al. · 2020

Background To evaluate the clinical relevance of the painful anterior apprehension test in shoulder instability. Methods We performed a retrospective study of 155 patients that underwent arthroscopic anterior Bankart repair between 2014–20…

Mesenchymal stem cell exosomes in bone regenerative strategies—a systematic review of preclinical studies Open

Si Heng Sharon Tan, Joshua Rui Yen Wong, Sharmaine Sim, Calvin Kai En Tjio, Keng Lin Wong , et al. · 2020

The ability of bone for regeneration has long been recognized. However, once beyond a critical size, spontaneous regeneration of bone is limited. Several studies have focused on enhancing bone regeneration by applying mesenchymal stromal/s…

Arthroscopic debridement has lower re-operation rates than arthrotomy in the treatment of acute septic arthritis of the knee: a meta-analysis Open

Taufiq Panjwani, Keng Lin Wong, Si Heng Sharon Tan, Zi Qiang Glen Liau, Narendra Vaidya , et al. · 2019

Chemoprophylaxis in addition to mechanical prophylaxis after total knee arthroplasty surgery does not reduce the incidence of venous thromboembolism Open

Jing Loong Moses Loh, Stephrene Chan, Keng Lin Wong, Sanjay De Mel, Eng Soo Yap · 2019

Correlations between ultrasonographic and subsequent radiographic findings of developmental dysplasia of the hips Open

Si Heng Sharon Tan, Chenghan Wu, Keng Lin Wong, James Hoi Po Hui · 2019

The current study suggests that ultrasonographic findings evaluated in the first 3 months of life have a close correlation with radiographic findings evaluated at 1 year of life. The ultrasonographic parameters showed an excellent negative…

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