Keng-Ru Lin
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View article: The RElationship of Advanced Education and ADherence (ReAHEAD) on antithrombotic in younger patients with non-valvular atrial fibrillation in Taiwan
The RElationship of Advanced Education and ADherence (ReAHEAD) on antithrombotic in younger patients with non-valvular atrial fibrillation in Taiwan Open
NCT04532528.
View article: DHX9 SUMOylation is required for the suppression of R-loop-associated genome instability
DHX9 SUMOylation is required for the suppression of R-loop-associated genome instability Open
RNA helicase DHX9 is essential for genome stability by resolving aberrant R-loops. However, its regulatory mechanisms remain unclear. Here we show that SUMOylation at lysine 120 (K120) is crucial for DHX9 function. Preventing SUMOylation a…
View article: ATR phosphorylates DHX9 at serine 321 to suppress R-loop accumulation upon genotoxic stress
ATR phosphorylates DHX9 at serine 321 to suppress R-loop accumulation upon genotoxic stress Open
Aberrant DNA/RNA hybrids (R-loops) formed during transcription and replication disturbances pose threats to genome stability. DHX9 is an RNA helicase involved in R-loop resolution, but how DHX9 is regulated in response to genotoxic stress …