Kengo Nishimura
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View article: Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury
Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury Open
There is a growing body of evidence that the delivery of cell-derived exosomes normally involved in intracellular communication can reduce secondary injury mechanisms after brain and spinal cord injury and improve outcomes. Exosomes are na…
View article: Risk factors and management of intraprocedural rupture during coil embolization of unruptured intracranial aneurysms: role of balloon guiding catheter
Risk factors and management of intraprocedural rupture during coil embolization of unruptured intracranial aneurysms: role of balloon guiding catheter Open
Introduction Intraprocedural rupture (IPR) is a serious complication of endovascular coil embolization of unruptured intracranial aneurysms (UIAs). Although outcomes after IPR are poor, methods to prevent subsequent neurological deteriorat…
View article: A Case of Isolated Superior Mesenteric Artery Dissection Resulting in Recurrent Necrosis of the Small Intestine
A Case of Isolated Superior Mesenteric Artery Dissection Resulting in Recurrent Necrosis of the Small Intestine Open
Isolated superior mesenteric artery dissection (ISMAD) is a rare cause of acute abdominal conditions. Most cases of ISMAD have a favorable prognosis, and only a few cases of ISMAD-associated intestinal necrosis have been reported. A 75-yea…
View article: A Case of Two Separate Surgical Repairs with Occlusion Balloon Catheter for an Isolated Internal Iliac Artery Aneurysm
A Case of Two Separate Surgical Repairs with Occlusion Balloon Catheter for an Isolated Internal Iliac Artery Aneurysm Open
症例は70歳，男性。孤立性左内腸骨動脈瘤破裂による出血性ショックに対してコイル塞栓直後に開腹下に空置術を施行した。術後瘤の拡大があったためコイル塞栓を施行したが瘤が再拡大しため空置術後3年目に破裂時同様にオクリュージョンバルン（OB）を併用して後腹膜経路で瘤内へ流入する動脈の結紮と瘤縫縮を施行した。OBを併用することで術中の出血のコントロールができ再手術を安全に施行できた。
View article: Safety and Efficacy of Intra-arterial Mesenchymal Stem Cell Therapy in an Endovascular Canine Model of Ischemic Stroke
Safety and Efficacy of Intra-arterial Mesenchymal Stem Cell Therapy in an Endovascular Canine Model of Ischemic Stroke Open
The safety and benefit of intra-arterial (IA) allogeneic Mesenchymal Stem Cells (MSCs) administered within 1-2 days of stroke in rodent models hold transformative potential for treating acute ischemic stroke (AIS). However, the lack of lar…
View article: A Case of a Systemic Lupus Erythematosus Patient with a Right Common Iliac Artery (CIA) Aneurysm after Endovascular Stenting for an Occluded Right CIA
A Case of a Systemic Lupus Erythematosus Patient with a Right Common Iliac Artery (CIA) Aneurysm after Endovascular Stenting for an Occluded Right CIA Open
症例は57歳，女性。全身性エリテマトーデスにてステロイドを長期内服中。2015年右総腸骨動脈（CIA）閉塞症に対して右CIAから右外腸骨動脈（EIA）にステントを留置された。2021年9月に左下肢間欠性跛行あり，CTより右CIA瘤，左CIA–EIA閉塞，腹部大動脈拡張と診断した。待機的に腹部正中切開にてステントを抜去後，腎動脈下腹部大動脈と両EIAとをY型人工血管で置換した。
View article: Early vascular responses to abluminal biodegradable polymer-coated versus circumferential durable polymer-coated newer-generation drug-eluting stents in humans: a pathologic study
Early vascular responses to abluminal biodegradable polymer-coated versus circumferential durable polymer-coated newer-generation drug-eluting stents in humans: a pathologic study Open
Background Recent clinical trials are testing strategies for short (1–3 months) dual antiplatelet therapy (DAPT) following newer-generation drug-eluting stent (DES) placement. However, the safety of short DAPT regimens is not supported by …
View article: Delayed diagnosis of septic shock due to comorbid severe pulmonary hypertension: a case report
Delayed diagnosis of septic shock due to comorbid severe pulmonary hypertension: a case report Open
View article: Visual complications after coil embolization of internal carotid artery aneurysms at the ophthalmic segment
Visual complications after coil embolization of internal carotid artery aneurysms at the ophthalmic segment Open
Background Coil embolization of aneurysms of the ophthalmic segment of the internal carotid artery (ICA-OphA ANs) has potential risks of visual complications. We analyzed this risk and focused on the relationship of the ophthalmic artery (…
View article: Retrospective analysis of serum albumin reduction after thoracoscopic esophagectomy for esophageal cancer
Retrospective analysis of serum albumin reduction after thoracoscopic esophagectomy for esophageal cancer Open
【目的】胸腔鏡下食道癌手術前後の血清アルブミン値の変化と関連する周術期因子を明らかにすること。【方法】2013年1月から2019年6月の間に姫路赤十字病院において食道癌に対して胸腔鏡下食道切除術を施行された患者121人を対象とした。術前血清アルブミン値と術翌日朝の血清アルブミン値から血清アルブミン値低下率を計算し，患者背景・周術期因子との関連について検討した。【結果】手術前後での血清アルブミン低下率の中央値は35.1％であった。重回帰分析の結果，手術時間の延長，術中出血量の…
View article: Development of a novel and rapid measurement system for growth differentiation factor-15, progranulin, and osteopontin in uterine sarcoma
Development of a novel and rapid measurement system for growth differentiation factor-15, progranulin, and osteopontin in uterine sarcoma Open
Uterine sarcomas are rare and aggressive gynecologic tumors with poor prognosis; therefore, early diagnosis is crucial for therapy. However, it is very difficult to distinguish uterine sarcomas from leiomyomas which are common benign uteri…
View article: Combination of high-resolution cone beam computed tomography and metal artefact reduction software: a new image fusion technique for evaluating intracranial stent apposition after aneurysm treatment
Combination of high-resolution cone beam computed tomography and metal artefact reduction software: a new image fusion technique for evaluating intracranial stent apposition after aneurysm treatment Open
We introduce a new imaging technique to improve visualisation of stent apposition after endovascular treatment of brain aneurysms employing high-resolution cone beam CT and three-dimensional digital subtraction angiography. After performin…
View article: Ruptured Abdominal Aortic Aneurysm with a Duplicated Inferior Vena Cava
Ruptured Abdominal Aortic Aneurysm with a Duplicated Inferior Vena Cava Open
We report a very rare case of a ruptured abdominal aortic aneurysm (AAA) with an anomaly of the inferior vena cava (IVC). The AAA was covered with a large hematoma and an expanded vein was on its left side. It was not until we could not lo…
View article: A Case of Cardiac Arrest during Cesarean Section in Which the Patient Was Diagnosed as Pulmonary Hypertension Associated with Systemic Lupus Erythematosus after the Surgery
A Case of Cardiac Arrest during Cesarean Section in Which the Patient Was Diagnosed as Pulmonary Hypertension Associated with Systemic Lupus Erythematosus after the Surgery Open
症例は34歳の女性で，妊娠36週で双胎妊娠・前期破水のため脊髄くも膜下麻酔による緊急帝王切開が施行された．術前検査に特記すべき異常はなく，妊娠中に呼吸循環系の症状は認めなかった．術中特に異常なく経過していたが，第2子娩出直後に心肺停止となった．直ちに心肺蘇生処置を開始し，数分後に心拍再開が得られた．手術終了後，ICUに入室した．術後の経胸壁心エコーで著明な右室拡大を認め，肺動脈カテーテル検査により肺高血圧症が判明した．特発性肺動脈性肺高血圧症と診断されたが，術後10カ月目に…
View article: Accuracy of Length of Virtual Stents in Treatment of Intracranial Wide-Necked Aneurysms
Accuracy of Length of Virtual Stents in Treatment of Intracranial Wide-Necked Aneurysms Open
Stent planning software allows 3D simulation of laser cut stents overlain on 3D-DSA images of vessels and may thus be useful for stent selection and deployment of laser cut stents during stent-assisted coiling of intracranial aneurysms.
View article: Ruptured Deep Femoral Artery Aneurysm Confused with an Incarcerated Inguinal Hernia: a Case of an Elderly Patient
Ruptured Deep Femoral Artery Aneurysm Confused with an Incarcerated Inguinal Hernia: a Case of an Elderly Patient Open
Deep femoral artery (DFA) aneurysms are rare. DFA is protected by the adductor canal, which may delay the diagnosis. Then, its early diagnosis may be difficult and it is possible to be misdiagnosis with incarcerated inguinal hernia, which …
View article: Multistage “Hybrid” (Open and Endovascular) Surgical Treatment of Vertebral Artery–Thrombosed Giant Aneurysm by Trapping and Thrombectomy
Multistage “Hybrid” (Open and Endovascular) Surgical Treatment of Vertebral Artery–Thrombosed Giant Aneurysm by Trapping and Thrombectomy Open
Based on pathologic and surgical anatomical characteristics, a combination of an endovascular procedure with 2-staged craniotomy for complete trapping, thrombectomy, and vasa vasorum obliteration could be considered a feasible way to treat…
View article: Estimated pretreatment hemodynamic prognostic factors of aneurysm recurrence after endovascular embolization
Estimated pretreatment hemodynamic prognostic factors of aneurysm recurrence after endovascular embolization Open
Our results suggest that hemodynamic factors may be associated with aneurysm recurrence among Pcom aneurysms. Velocity and flow rate in the Pcom may be a pretreatment prognostic factor for aneurysm recurrence after endovascular treatment.
View article: Carotid Artery Stenting for Symptomatic Stenosis of the Cervical Carotid Artery Associated with Persistent Primitive Hypoglossal Artery: A Case Report
Carotid Artery Stenting for Symptomatic Stenosis of the Cervical Carotid Artery Associated with Persistent Primitive Hypoglossal Artery: A Case Report Open
Objective: A case of symptomatic cervical carotid artery stenosis with persistent primitive hypoglossal artery (PPHA) treated by carotid artery stenting (CAS) with appropriate embolic protection is reported.
View article: Modified Batista Procedure for Idiopathic Dilated Cardiomyopathy: Report of a Case
Modified Batista Procedure for Idiopathic Dilated Cardiomyopathy: Report of a Case Open
The surgical indications for dilated cardiomyopathy (DCM) remain controversial, not including cardiac transplantation and mechanical circulatory support. We describe a case of idiopathic DCM that underwent successful surgical treatment usi…
View article: Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization
Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization Open
Tailor-made shaping of microcatheters may facilitate easier and safer procedures in coil embolization of intracranial aneurysm.
View article: A Case of True Brachial Artery Aneurysm with Severe Left Upper Limb Ischemia
A Case of True Brachial Artery Aneurysm with Severe Left Upper Limb Ischemia Open
Brachial artery (BA) aneurysms are rare, and most are false aneurysms. Although true BA aneurysms have been reported, most have been reported without symptoms. A 65-year-old man was referred due to a left upper limb mass with rest pain and…
View article: E-032 Combination of High Resolution Cone-beam CT and 3D DSA for the Evaluation of Intracranial Stents used for Aneurysm Treatment
E-032 Combination of High Resolution Cone-beam CT and 3D DSA for the Evaluation of Intracranial Stents used for Aneurysm Treatment Open
Purpose Incomplete stent apposition after the treatment of brain aneurysm can increase the risk of thromboembolic complications and remains to be the major concern during the procedure. Utilizing the high resolution cone-beam CT (HR-CBCT) …
View article: Revascularization for acute blunt popliteal artery injury
Revascularization for acute blunt popliteal artery injury Open
We report a case of revascularization involving a patient with open fracture of the right femur due to acute blunt popliteal artery injury.
View article: A Case of Heparin-Induced Thrombocytopenia Type 2 after Repair of Juxtarenal Abdominal Aortic Aneurysm
A Case of Heparin-Induced Thrombocytopenia Type 2 after Repair of Juxtarenal Abdominal Aortic Aneurysm Open
Heparin-induced thrombocytopenia (HIT) is still a relatively uncommon condition and it is not well known how to administer argatroban during continuous hemodiafiltration (CHDF). A 72-year-old man required CHDF with heparin because of the o…
View article: An Inflammatory Pseudotumor Arising from the Mitral Valve
An Inflammatory Pseudotumor Arising from the Mitral Valve Open
We herein report a rare case of an inflammatory pseudotumor arising from the mitral valve.A 58-yearold man who was undergoing maintenance dialysis was referred to us due to the presence of a tumor mass attached to the mitral valve.It was a…
View article: Endovascular Treatment of Left Subclavian Artery Pseudoaneurysm after Clavicle Fracture in an Elderly Adult with a 40-Year History of Behçet’s Disease
Endovascular Treatment of Left Subclavian Artery Pseudoaneurysm after Clavicle Fracture in an Elderly Adult with a 40-Year History of Behçet’s Disease Open
Behçet's disease (BD) is a rare chronic systemic vasculitis of unknown etiology that presents in young adults. We report a very rare case of a left subclavian artery pseudoaneurysm identified after a left clavicle fracture in a 70-year-old…