Kenji Momo
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View article: Effectiveness of Statins for Oxaliplatin‐Induced Peripheral Neuropathy: A Multicenter Retrospective Observational Study
Effectiveness of Statins for Oxaliplatin‐Induced Peripheral Neuropathy: A Multicenter Retrospective Observational Study Open
Chemotherapy‐induced peripheral neuropathy, including oxaliplatin‐induced peripheral neuropathy (OIPN), can have a negative impact on patient quality of life for months or even years after discontinuation of chemotherapy. Statins are commo…
View article: A Case of Metronidazole‐Induced Encephalopathy: Can Encephalopathy be Distinguished From Delirium Like Symptoms?
A Case of Metronidazole‐Induced Encephalopathy: Can Encephalopathy be Distinguished From Delirium Like Symptoms? Open
Although the treatment strategies differ significantly, metronidazole‐induced encephalopathy and delirium manifest with similar clinical symptoms. Therefore, the potential risk of encephalopathy should be considered when treating patients …
View article: Kampo medicine inducing drug-induced liver injury: A case report and systematic review
Kampo medicine inducing drug-induced liver injury: A case report and systematic review Open
Kampo medicine, comprising various conventional crude drug products, poses challenges in identifying adverse event causality. We present a case of severe liver injury following the administration of Saibokuto and attempted to identify the …
View article: Different Patterns of Platelet Count Fluctuation in Response to Various Anticancer Chemotherapies among Patient with Bladder Cancer
Different Patterns of Platelet Count Fluctuation in Response to Various Anticancer Chemotherapies among Patient with Bladder Cancer Open
Introduction: In general, platelet counts fluctuate in cancer patients receiving anticancer therapy. It may include thrombocytopenia caused by bone marrow suppression due to cytotoxic anticancer agents and thrombocytosis due to rebound dur…
View article: Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain
Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain Open
Key Clinical Message Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small‐cell lung cancer who developed SIADH with hypouricemia …
View article: Public Knowledge and Attitude of Caregivers Regarding Leftover Medications for Children under 6 Years of Age in Japan: A Descriptive Study on a Nationwide Exploratory Questionnaire Survey to Caregivers
Public Knowledge and Attitude of Caregivers Regarding Leftover Medications for Children under 6 Years of Age in Japan: A Descriptive Study on a Nationwide Exploratory Questionnaire Survey to Caregivers Open
Leftover medications are a global concern for harm to health and inadequate medical care costs. However, information on leftover medicines and their inappropriate use in children in Japan is lacking. We aimed to clarify the proportion of l…
View article: The significance of therapeutic drug monitoring in detecting low medication adherence in patients with cancer: A case study of cabozantinib
The significance of therapeutic drug monitoring in detecting low medication adherence in patients with cancer: A case study of cabozantinib Open
Key Clinical Message Maintaining good medication adherence is important for providing desirable outcomes from medication therapy. We showed that therapeutic drug monitoring (TDM) contributed to the identification of low medication adherenc…
View article: A severe tremor caused by a beta2 agonist in a patient with asthma‐chronic obstructive pulmonary disease overlap
A severe tremor caused by a beta2 agonist in a patient with asthma‐chronic obstructive pulmonary disease overlap Open
Key Clinical Message A 46‐year‐old male developed respiratory distress due to asthma‐chronic obstructive pulmonary disease overlap and experienced severe tremor caused by beta2 agonist inhalant. We present our successful experience with ti…
View article: Risk Factors for Treatment Transition in Patients with Low-Risk Atrial Fibrillation Patients Undergoing Anticoagulation Monotherapy: A Large Claims Database Study in Japan
Risk Factors for Treatment Transition in Patients with Low-Risk Atrial Fibrillation Patients Undergoing Anticoagulation Monotherapy: A Large Claims Database Study in Japan Open
The global prevalence of atrial fibrillation (AF) is rising, paralleling increased life expectancy. Early rhythm control benefits AF management. However, in low-risk, often asymptomatic, AF patients, anticoagulant monotherapy is the select…
View article: Combined sepsis‐ and renal dysfunction‐induced hypoglycaemia in an older patient taking cibenzoline
Combined sepsis‐ and renal dysfunction‐induced hypoglycaemia in an older patient taking cibenzoline Open
Key Clinical Message An 86‐year‐old geriatric patient with sepsis presented cibenzoline‐induced hypoglycaemia, although within the boundary range of cibenzoline blood concentration. Abstract An 86‐year‐old geriatric patient taking cibenzol…
View article: Self-controlled Case Series Study for Acute Kidney Injury after Starting Proton Pump Inhibitors or Potassium-Competitive Acid Blocker in Patients with Cancer Using a Large Claims Database
Self-controlled Case Series Study for Acute Kidney Injury after Starting Proton Pump Inhibitors or Potassium-Competitive Acid Blocker in Patients with Cancer Using a Large Claims Database Open
To investigate the risk of acute kidney injury (AKI) in patients with cancer following the initiation of proton pump inhibitors (PPIs) and potassium-competitive acid blocker (PCAB), considering sex and anti-cancer drug use. We conducted a …
View article: Identifying causative medications for agranulocytosis: A case report of an older adult with cerebral infarction
Identifying causative medications for agranulocytosis: A case report of an older adult with cerebral infarction Open
Key Clinical Message Most drugs that cause adverse events are difficult to identify in critically ill patients undergoing polypharmacy. We share our experience in identifying the causative drug among four suspect drugs administered during …
View article: Severe thrombocytopaenia caused by trastuzumab emtansine in a patient with breast cancer: A case report
Severe thrombocytopaenia caused by trastuzumab emtansine in a patient with breast cancer: A case report Open
We present the case of a 48-year-old woman with human epidermal growth factor receptor 2- and hormone receptor-positive left early breast cancer who developed severe thrombocytopaenia and moderate liver dysfunction after administration of …
View article: Survey on prescriptions of similar-looking formulations to patients requiring ophthalmological operations
Survey on prescriptions of similar-looking formulations to patients requiring ophthalmological operations Open
The present study aimed to determine the frequency of drug use with devices, such as inhalers and self-injectors, and use of two or more topical agents with similar formulations in patients who required ophthalmological operations. We retr…
View article: Transient <scp>EDTA</scp>‐dependent pseudothrombocytopenia and ulcerative colitis recurrence during chemotherapy: A case of misleading platelet count results attributable to a laboratory artifact
Transient <span>EDTA</span>‐dependent pseudothrombocytopenia and ulcerative colitis recurrence during chemotherapy: A case of misleading platelet count results attributable to a laboratory artifact Open
Key Clinical Message EDTA‐dependent pseudothrombocytopenia as well as myelosuppression should be suspected when thrombocytopenia occurs in patients with autoimmune disease during chemotherapy. Abstract A patient with pancreatic cancer and …
View article: A super‐geriatric patient with gastrostomy underwent life‐threatening prothrombin time‐international normalized ratio prolongation by warfarin following fasting and antibiotic therapy
A super‐geriatric patient with gastrostomy underwent life‐threatening prothrombin time‐international normalized ratio prolongation by warfarin following fasting and antibiotic therapy Open
Key Clinical Message A 97‐year‐old woman with gastrostomy had a drastic enhancement for PT‐INR after starting antibiotic therapy. Possible causes include (1) vitamin K deficiency due to fasting and (2) a combination of warfarin and antibio…
View article: Assessment of Diagnosis Timing of Attention-Deficit/Hyperactivity Disorder in Working-Age Workers with Psychiatric Diseases Using Large Claims Data
Assessment of Diagnosis Timing of Attention-Deficit/Hyperactivity Disorder in Working-Age Workers with Psychiatric Diseases Using Large Claims Data Open
Attention deficit/hyperactivity disorder (ADHD) is a common developmental disorder. This study aims to clarify the timing of diagnosis of ADHD in working-age workers with psychiatric comorbidities using large claims data in Japan. Based on…
View article: Descriptive Study on a Nationwide Exploratory Questionnaire Survey of Emergency Contraceptive Pills and Their Sexual History and Knowledge in Japan
Descriptive Study on a Nationwide Exploratory Questionnaire Survey of Emergency Contraceptive Pills and Their Sexual History and Knowledge in Japan Open
A shift towards obtaining emergency contraceptives without a prescription have been discussed in Japan. In response to this social background, we aimed at investigating the background of sexual intercourse, emergency contraceptive use, and…
View article: Risk Assessment for Heart Failure in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase 4 Inhibitor Using a Large Claims Dataset
Risk Assessment for Heart Failure in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase 4 Inhibitor Using a Large Claims Dataset Open
Heart failure is a prevalent comorbidity in patients with diabetes mellitus (DM). However, it is unclear whether the risk factors for heart failure in DM patients treated with dipeptidyl peptidase-4 (DPP-4) inhibitors are the same as those…
View article: Dilemma Facing Patients Aged 75 Years and Older on Fluid Restriction When Drug Package Inserts Advise Use of a Lot of Water: A Cross-Sectional, Descriptive, and Hypothesis-Generating Study Using a Large Claims Database
Dilemma Facing Patients Aged 75 Years and Older on Fluid Restriction When Drug Package Inserts Advise Use of a Lot of Water: A Cross-Sectional, Descriptive, and Hypothesis-Generating Study Using a Large Claims Database Open
Of patients 75 years and older with disease likely requiring water restriction, 5.4% faced the dilemma of following advice to restrict fluid intake due to their diagnoses or to adhere to instructions in drug package inserts to have abundan…
View article: Dexamethasone to prednisolone rotation relieved hiccups in colorectal cancer patient continuing teleworking during anticancer therapy
Dexamethasone to prednisolone rotation relieved hiccups in colorectal cancer patient continuing teleworking during anticancer therapy Open
Key Clinical Message We present a case of chemotherapy‐induced hiccups that were alleviated by steroid rotation. Hiccups are often overlooked, but they have an impact on the patient's quality of life. In the COVID‐19 era, web‐based telewor…
View article: #3605 TREATMENT OF HYPERTENSION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE PATIENTS: A COMPARISON OF POLISH AND JAPANESE MEDICATION PATTERNS
#3605 TREATMENT OF HYPERTENSION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE PATIENTS: A COMPARISON OF POLISH AND JAPANESE MEDICATION PATTERNS Open
Background and Aims Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease and fourth case of kidney failure worldwide. Treatment options for ADPKD include therapy with vasopressin (ADH) receptor 2…
View article: Exploring for Drug Development Seeds for Children Using a Large Claims Data—Survey for Powderization or Decapsulation of Oral Tablets or Capsule Formula in Children—
Exploring for Drug Development Seeds for Children Using a Large Claims Data—Survey for Powderization or Decapsulation of Oral Tablets or Capsule Formula in Children— Open
Medical big data is accumulated numerous medical related data day by day. These data may have tips for new approach for drug development. Authors tried to find drug-development-needs in children using medical big data analysis with prescri…
View article: Retrospective analysis of atlantoaxial rotatory fixation describing age distribution and gender ratio in children and adolescents: A preliminary report
Retrospective analysis of atlantoaxial rotatory fixation describing age distribution and gender ratio in children and adolescents: A preliminary report Open
This is the first report to describe the characteristics of the study population of AARF. Males were more likely to suffer from AARF than females. Furthermore, age (in months) at AARF onset was significantly higher in males than in females…
View article: Negative effects of rivaroxaban observed in a patient with multiple common risks triggered by a bicycle accident
Negative effects of rivaroxaban observed in a patient with multiple common risks triggered by a bicycle accident Open
The negative effects of anticoagulants are well‐known in patients with renal impairment, drug–drug interaction, lower physical conditions, and multiple comorbidities. We highlight that even in patients with controllable multiple risks for …