Kenneth L. Koch
YOU?
Author Swipe
View article: Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity
Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity Open
View article: Single cell atlas of human gastric muscle immune cells and macrophage-driven changes in idiopathic gastroparesis
Single cell atlas of human gastric muscle immune cells and macrophage-driven changes in idiopathic gastroparesis Open
Gastrointestinal immune cells, particularly muscularis macrophages (MM) interact with the enteric nervous system and influence gastrointestinal motility. Here we determine the human gastric muscle immunome and its changes in patients with …
View article: A pilot genome‐wide association study meta‐analysis of gastroparesis
A pilot genome‐wide association study meta‐analysis of gastroparesis Open
Background Gastroparesis (GP) is characterized by delayed gastric emptying in the absence of mechanical obstruction. Objective Genetic predisposition may play a role; however, investigation at the genome‐wide level has not been performed. …
View article: Relationships among intragastric meal distribution during gastric emptying scintigraphy, water consumption during water load satiety testing, and symptoms of gastroparesis
Relationships among intragastric meal distribution during gastric emptying scintigraphy, water consumption during water load satiety testing, and symptoms of gastroparesis Open
IMD 0 and WLST were assessed for their clinical utility in assessing patients with symptoms of gastroparesis. Low IMD 0 is associated with less gastric retention and less heartburn. Volume of water consumed during WLST, while associated wi…
View article: Buspirone for early satiety and symptoms of gastroparesis: A multi‐centre, randomised, placebo‐controlled, double‐masked trial ( <scp>BESST</scp> )
Buspirone for early satiety and symptoms of gastroparesis: A multi‐centre, randomised, placebo‐controlled, double‐masked trial ( <span>BESST</span> ) Open
Summary Background Patients with gastroparesis and related disorders have symptoms including early satiety, postprandial fullness and bloating. Buspirone, a 5‐HT 1 receptor agonist, may improve fundic accommodation. Aim To determine if bus…
View article: Characteristics and outcomes of patients with gastroparesis using enteral and/or exclusive parenteral nutrition
Characteristics and outcomes of patients with gastroparesis using enteral and/or exclusive parenteral nutrition Open
Background Patients with gastroparesis (Gp) may need enteral nutrition (EN) or exclusive parenteral nutrition (PN). Among patients with Gp, we aimed to (1) identify the frequency of EN and exclusive PN use and (2) explore characteristics o…
View article: Progress in Gastroparesis - A Narrative Review of the Work of the Gastroparesis Clinical Research Consortium
Progress in Gastroparesis - A Narrative Review of the Work of the Gastroparesis Clinical Research Consortium Open
View article: Postprandial symptoms in patients with symptoms of gastroparesis: roles of gastric emptying and accommodation
Postprandial symptoms in patients with symptoms of gastroparesis: roles of gastric emptying and accommodation Open
Patients with delayed and normal gastric emptying (GE) had similar symptom profiles during gastric emptying scintigraphy (GES). Idiopathic patients with symptoms of gastroparesis had less gastric retention by GES; but more symptoms after G…
View article: Effect of liquid and solid test meals on symptoms and gastric myoelectrical activity in patients with gastroparesis and functional dyspepsia
Effect of liquid and solid test meals on symptoms and gastric myoelectrical activity in patients with gastroparesis and functional dyspepsia Open
Background Patients with gastroparesis (GP) and functional dyspepsia (FD) have similar symptoms, but the pathophysiology of postprandial symptoms remains uncertain. Aims To compare symptoms and gastric myoelectrical activity (GMA) after li…
View article: Prevalence and clinical correlates of antinuclear antibody in patients with gastroparesis
Prevalence and clinical correlates of antinuclear antibody in patients with gastroparesis Open
Background Autoimmunity may play a role in the pathogenesis of gastroparesis in a subset of patients. Antinuclear antibody (ANA) testing is often used to screen for autoimmune disorders. Aims 1) Determine prevalence of a positive ANA in pa…
View article: Effect of Domperidone Therapy on Gastroparesis Symptoms: Results of a Dynamic Cohort Study by NIDDK Gastroparesis Consortium
Effect of Domperidone Therapy on Gastroparesis Symptoms: Results of a Dynamic Cohort Study by NIDDK Gastroparesis Consortium Open
View article: Effects of Spinal Cord Stimulation in Patients with Chronic Nausea, Vomiting, and Refractory Abdominal Pain
Effects of Spinal Cord Stimulation in Patients with Chronic Nausea, Vomiting, and Refractory Abdominal Pain Open
SCS may be an effective therapy for long-term treatment of symptoms for those patients afflicted with chronic nausea, vomiting, and refractory abdominal pain.
View article: Functional Dyspepsia and Gastroparesis in Tertiary Care are Interchangeable Syndromes With Common Clinical and Pathologic Features
Functional Dyspepsia and Gastroparesis in Tertiary Care are Interchangeable Syndromes With Common Clinical and Pathologic Features Open
View article: Factors that contribute to the impairment of quality of life in gastroparesis
Factors that contribute to the impairment of quality of life in gastroparesis Open
Background Understanding factors that impair quality of life (QOL) in gastroparesis is important for clinical management. Aims: (a) Determine QOL in patients with gastroparesis; (b) Determine factors that impair QOL. Methods Gastroparetic …
View article: Constipation in Patients With Symptoms of Gastroparesis: Analysis of Symptoms and Gastrointestinal Transit
Constipation in Patients With Symptoms of Gastroparesis: Analysis of Symptoms and Gastrointestinal Transit Open
View article: Body weight in patients with idiopathic gastroparesis
Body weight in patients with idiopathic gastroparesis Open
Background The classic clinical picture of gastroparesis is a symptomatic patient losing weight. In addition, a number of patients with delayed gastric emptying are obese and/or gaining weight. Our aim was to investigate the factors impact…
View article: In Memoriam: Robert M. Stern
In Memoriam: Robert M. Stern Open
Robert “Bob” M. Stern June 18, 1937-June 13, 2020. Robert M. Stern, 83, of State College, Pennsylvania, died on Saturday, June 13, 2020. He is survived by his wife of 59 years, Wilma Olch Stern, and his daughters Jessica Leigh Benjamin and…
View article: In memoriam: Robert M. Stern (1937–2020)
In memoriam: Robert M. Stern (1937–2020) Open
Robert M. Stern 1937–2020 Robert “Bob” M. Stern June 18, 1937-June 13, 2020 Robert M. Stern, 83, of State College died on Saturday, June 13, 2020. He is survived by his wife of 59 years, Wilma Olch Stern, and his daughters Jessica Leigh Be…
View article: Autonomic function in gastroparesis and chronic unexplained nausea and vomiting: Relationship with etiology, gastric emptying, and symptom severity
Autonomic function in gastroparesis and chronic unexplained nausea and vomiting: Relationship with etiology, gastric emptying, and symptom severity Open
Background Autonomic dysfunction can be present in patients with idiopathic and diabetic gastroparesis. The role of autonomic dysfunction relating to gastric emptying and upper gastrointestinal symptoms in patients with gastroparesis and c…
View article: Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus
Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus Open
View article: Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit
Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit Open
View article: Delayed Gastric Emptying Associates With Diabetic Complications in Diabetic Patients With Symptoms of Gastroparesis
Delayed Gastric Emptying Associates With Diabetic Complications in Diabetic Patients With Symptoms of Gastroparesis Open
OBJECTIVES: Diabetic gastroparesis (Gp) occurs more often in type 1 diabetes mellitus (T1DM) than in type 2 diabetes mellitus (T2DM). Other diabetic end-organ complications include peripheral neuropathy, nephropathy, and retinopathy (toget…
View article: Effectiveness of gastric electrical stimulation in gastroparesis: Results from a large prospectively collected database of national gastroparesis registries
Effectiveness of gastric electrical stimulation in gastroparesis: Results from a large prospectively collected database of national gastroparesis registries Open
Background Gastric electrical stimulation (GES) for treating gastroparesis symptoms is controversial. Methods We studied 319 idiopathic or diabetic gastroparesis symptom patients from the Gastroparesis Clinical Research Consortium (GpCRC) …
View article: Satiety testing in diabetic gastroparesis: Effects of insulin pump therapy with continuous glucose monitoring on upper gastrointestinal symptoms and gastric myoelectrical activity
Satiety testing in diabetic gastroparesis: Effects of insulin pump therapy with continuous glucose monitoring on upper gastrointestinal symptoms and gastric myoelectrical activity Open
Background Symptoms induced by caloric or non‐caloric satiety test meals and gastric myoelectrical activity (GMA) have not been studied in patients with diabetic gastroparesis (DGP) before and after intense glucose management. Aims We dete…
View article: Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis
Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis Open
Macrophage-based immune dysregulation plays a critical role in development of delayed gastric emptying in diabetic mice. Loss of anti-inflammatory macrophages and increased expression of genes associated with pro-inflammatory macrophages h…
View article: Gastric Myoelectrical Activity and Autonomic Nervous System Abnormalities in Patients with Chronic Unexplained Nausea and Vomiting and in Patients with Gastroparesis
Gastric Myoelectrical Activity and Autonomic Nervous System Abnormalities in Patients with Chronic Unexplained Nausea and Vomiting and in Patients with Gastroparesis Open
Background: Patients with chronic unexplained nausea and vomiting (CUNV) and Gastroparesis (GP) have similar symptoms, suggesting they share pathophysiological abnormalities along a continuum of disease.Objectives: To determine the inciden…
View article: Mo1589 – Gastric Retention in Gastroparesis: Relationship of Proximal, Distal, and Total Gastric Retention to Symptoms
Mo1589 – Gastric Retention in Gastroparesis: Relationship of Proximal, Distal, and Total Gastric Retention to Symptoms Open
View article: Mo1590 – Body Weight and Body Weight Changes in Gastroparesis: Relationship to Symptoms of Gastroparesis
Mo1590 – Body Weight and Body Weight Changes in Gastroparesis: Relationship to Symptoms of Gastroparesis Open
View article: Mo1592 – Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit
Mo1592 – Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit Open
View article: Abdominal Pain in Patients with Gastroparesis: Associations with Gastroparesis Symptoms, Etiology of Gastroparesis, Gastric Emptying, Somatization, and Quality of Life
Abdominal Pain in Patients with Gastroparesis: Associations with Gastroparesis Symptoms, Etiology of Gastroparesis, Gastric Emptying, Somatization, and Quality of Life Open