Kent Kanao
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View article: Few-Shot Learning for Prostate Cancer Detection on MRI: Comparative Analysis with Radiologists’ Performance
Few-Shot Learning for Prostate Cancer Detection on MRI: Comparative Analysis with Radiologists’ Performance Open
Deep-learning models for prostate cancer detection typically require large datasets, limiting clinical applicability across institutions due to domain shift issues. This study aimed to develop a few-shot learning deep-learning model for pr…
View article: Efficacy of photodynamic diagnosis for non-muscle invasive bladder cancer: Exploratory subject-based analysis in a prospective, single-arm, multicenter phase III trial
Efficacy of photodynamic diagnosis for non-muscle invasive bladder cancer: Exploratory subject-based analysis in a prospective, single-arm, multicenter phase III trial Open
This study is the first to demonstrate that PDD's efficacy is maintained up to 8 h after oral 5-ALA administration and indicates that PDD improves the detection rate of bladder cancer, potentially optimizing risk stratification and offerin…
View article: Few-Shot Learning for Prostate Cancer Detection on MRI: Comparative Analysis with Radiologists’ Performance
Few-Shot Learning for Prostate Cancer Detection on MRI: Comparative Analysis with Radiologists’ Performance Open
Background Deep-learning models for prostate cancer detection often require large datasets, which can be challenging to obtain and may lead to domain shift issues in various clinical settings. Purpose This study aimed to develop a deep-lea…
View article: Choroidal Metastasis From Papillary Renal Cell Carcinomas: A Case Report and a Review of the Literature
Choroidal Metastasis From Papillary Renal Cell Carcinomas: A Case Report and a Review of the Literature Open
Choroidal metastasis originating from renal cell carcinomas (RCCs) is rare. To the best of our knowledge, 31 cases of choroidal metastasis from RCC have been reported in the English literature as of January 31, 2024. Nevertheless, physicia…
View article: Aggressive variant prostate cancer with multiple subcutaneous metastases: a case report
Aggressive variant prostate cancer with multiple subcutaneous metastases: a case report Open
A 71-year-old man with bone metastasis of hormone-sensitive prostate cancer was treated with androgen deprivation therapy and apalutamide. Radium-223 and radiation therapy were administered after it become castration resistant. Although pr…
View article: New risk stratification for adjuvant nivolumab for high‐risk muscle‐invasive urothelial carcinoma
New risk stratification for adjuvant nivolumab for high‐risk muscle‐invasive urothelial carcinoma Open
Objectives We aim to evaluate the risk of recurrence after neoadjuvant chemotherapy followed by radical cystectomy, particularly in ypT2 disease in patients with urothelial carcinoma, because it is not clear if all eligible patients with h…
View article: Efficacy of abiraterone acetate for high-risk hormone-naïve metastatic prostate cancer: A comparison with combined androgen blockade therapy with bicalutamide and androgen deprivation therapy alone
Efficacy of abiraterone acetate for high-risk hormone-naïve metastatic prostate cancer: A comparison with combined androgen blockade therapy with bicalutamide and androgen deprivation therapy alone Open
Background The treatment landscape for men with metastatic hormone-naïve prostate cancer (mHNPC) has dramatically changed with the approval of next-generation anti-androgen drugs. We compared the treatment efficacy of abiraterone with that…
View article: Case Study: A Japanese patient with metastatic renal cell carcinoma who achieved long‐term treatment‐free survival with pembrolizumab and axitinib in the KEYNOTE‐426 phase III trial of pembrolizumab and axitinib versus sunitinib
Case Study: A Japanese patient with metastatic renal cell carcinoma who achieved long‐term treatment‐free survival with pembrolizumab and axitinib in the KEYNOTE‐426 phase III trial of pembrolizumab and axitinib versus sunitinib Open
Introduction Our patient treated with pembrolizumab and axitinib is one of the longest survivors in Japan on KEYNOTE 426, despite adverse events, including delayed‐onset hepatitis. We herein present a detailed clinical course and short dis…
View article: Efficacy of Abiraterone Acetate For High-Risk Hormone-Naïve Metastatic Prostate Cancer: A Comparison With Combined Androgen Blockade Therapy With Bicalutamide And Androgen Deprivation Therapy Alone
Efficacy of Abiraterone Acetate For High-Risk Hormone-Naïve Metastatic Prostate Cancer: A Comparison With Combined Androgen Blockade Therapy With Bicalutamide And Androgen Deprivation Therapy Alone Open
Background : The treatment landscape for men with metastatic hormone-naïve prostate cancer (mHNPC) has dramatically changed with the approval of next-generation anti-androgen drugs. We compared the treatment efficacy of abiraterone with th…
View article: Safety of adjuvant gemcitabine plus cisplatin chemotherapy in a patient with bilateral ureteral cancer undergoing hemodialysis
Safety of adjuvant gemcitabine plus cisplatin chemotherapy in a patient with bilateral ureteral cancer undergoing hemodialysis Open
An 80 year old Japanese man with bilateral ureteral cancer underwent laparoscopic bilateral nephroureterectomy and lymph-node dissection. The pathological stage of the left and right ureteral tumors was pT3pN0M0. He received two courses of…
View article: Laparoendoscopic single‐site simple nephrectomy and reduced port procedure for inflammatory nonfunctioning kidney
Laparoendoscopic single‐site simple nephrectomy and reduced port procedure for inflammatory nonfunctioning kidney Open
Introduction To describe laparoendoscopic single‐site simple nephrectomy and reduced port simple nephrectomy for inflammatory nonfunctioning kidney. Case presentation Case 1: a 58‐year‐old female with fever was referred to our hospital. Co…
View article: Prognostic Stratification of the IMDC Intermediate Risk Group After Treatment With First-line Molecular-targeted Therapy for Metastatic Renal Cell Carcinoma
Prognostic Stratification of the IMDC Intermediate Risk Group After Treatment With First-line Molecular-targeted Therapy for Metastatic Renal Cell Carcinoma Open
The novel stratification presented in this study could be a useful tool for further prognostication of patients with mRCC classified into the intermediate risk group according to the IMDC model after first-line molecular-targeted therapy.
View article: Dorsal Vein Complex Preserving Technique During Robot-Assisted Radical Prostatectomy
Dorsal Vein Complex Preserving Technique During Robot-Assisted Radical Prostatectomy Open
Background: Recently, two techniques of robot-assisted radical prostatectomy (RARP), which preserve dorsal vein complex (DVC), endopelvic fascia, and full neurovascular bundle (NVB), through anterior approach were reported. The techniques …
View article: A case of castration-resistant prostate cancer with liver metastases achieved a complete response by docetaxel chemotherapy
A case of castration-resistant prostate cancer with liver metastases achieved a complete response by docetaxel chemotherapy Open
Castration-resistant prostate cancer (CRPC) patients with liver metastases have an extremely poor prognosis. Herein, we report a rare patient who achieved a complete response by docetaxel chemotherapy for this aggressive disease. A 67-year…
View article: Efficacy of Nivolumab Plus Ipilimumab in a Patient With Renal Cell Carcinoma Concomitant With Cardiac Metastasis: A Case Report
Efficacy of Nivolumab Plus Ipilimumab in a Patient With Renal Cell Carcinoma Concomitant With Cardiac Metastasis: A Case Report Open
This successful case suggests that ICIs might provide a better outcome even for patients with cardiac metastasis of RCC, and that FDG-PET/CT scan might be useful for therapeutic assessment, as well as diagnosis.
View article: A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid
A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid Open
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer. We experienced an intriguing case, in which bladder cancer infiltrated into the ri…
View article: Optimal Timing of Cabazitaxel Introduction for Japanese Patients With Metastatic Castration-resistant Prostate Cancer
Optimal Timing of Cabazitaxel Introduction for Japanese Patients With Metastatic Castration-resistant Prostate Cancer Open
A comparatively low PSA value could be an alternative index suggesting the optimal timing for cabazitaxel introduction.
View article: Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells
Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells Open
Docetaxel (DOC) is one of the most effective chemotherapeutic agents against castration‑resistant prostate cancer (CRPC). Despite an impressive initial clinical response, the majority of patients eventually develop resistance to DOC. In tu…
View article: Impact of a novel biopsy instrument with a 25‐mm side‐notch needle on the detection of prostate cancer in transrectal biopsy
Impact of a novel biopsy instrument with a 25‐mm side‐notch needle on the detection of prostate cancer in transrectal biopsy Open
Objectives To evaluate the impact of a novel biopsy instrument that extends the length of the side‐notch on the detection of prostate cancer in transrectal needle biopsy. Methods We collaborated with a biopsy needle manufacturer and develo…
View article: PD64-09 A LONG TERM COMPARISON OF PERSISTENCE OF DRUG THERAPY IN 1,970 PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA
PD64-09 A LONG TERM COMPARISON OF PERSISTENCE OF DRUG THERAPY IN 1,970 PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA Open
You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology III1 Apr 2018PD64-09 A LONG TERM COMPARISON OF PERSISTENCE OF DRUG THERAPY IN 1,970 PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA Keishi Kajikawa…
View article: MP05-07 SHOULD GLEASON SCORE AT THE POSITIVE SURGICAL MARGIN APPEAR ON THE PATHOLOGY REPORT FOR ROBOT-ASSISTED RADICAL PROSTATECTOMY?
MP05-07 SHOULD GLEASON SCORE AT THE POSITIVE SURGICAL MARGIN APPEAR ON THE PATHOLOGY REPORT FOR ROBOT-ASSISTED RADICAL PROSTATECTOMY? Open
You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I1 Apr 2018MP05-07 SHOULD GLEASON SCORE AT THE POSITIVE SURGICAL MARGIN APPEAR ON THE PATHOLOGY REPORT FOR ROBOT-ASSISTED RADICAL PROSTATECTOMY? Kent Kanao, Miho…
View article: MP55-10 IMPORTANCE OF BACTERIAL STONE CULTURE AT TRANSURETHRAL LITHOTRIPSY: WHICH CASES REQUIRE BACTERIAL STONE CULTURE?
MP55-10 IMPORTANCE OF BACTERIAL STONE CULTURE AT TRANSURETHRAL LITHOTRIPSY: WHICH CASES REQUIRE BACTERIAL STONE CULTURE? Open
You have accessJournal of UrologyStone Disease: Surgical Therapy II1 Apr 2018MP55-10 IMPORTANCE OF BACTERIAL STONE CULTURE AT TRANSURETHRAL LITHOTRIPSY: WHICH CASES REQUIRE BACTERIAL STONE CULTURE? Genya Nishikawa, Kogenta Nakamura, Ikuo K…