Keon Wook Kang
YOU?
Author Swipe
View article: Novel Near-Infrared Probe for Monitoring Lipid Peroxidation-Mediated Viscosity Change in Ferroptotic Hepatocytes
Novel Near-Infrared Probe for Monitoring Lipid Peroxidation-Mediated Viscosity Change in Ferroptotic Hepatocytes Open
Our findings suggest that TTM-4 enables monitoring of ferroptosis in MASLD and would aid in early MASH diagnosis.
View article: Clinical Characteristics Associated with High [68Ga]Ga-PSMA-11 Uptake and Preliminary Therapeutic Outcomes in Patients with Metastatic Adenoid Cystic Carcinoma
Clinical Characteristics Associated with High [68Ga]Ga-PSMA-11 Uptake and Preliminary Therapeutic Outcomes in Patients with Metastatic Adenoid Cystic Carcinoma Open
Purpose Adenoid cystic carcinoma (ACC) is a rare cancer that arises from the salivary glands. Recent studies have shown that prostate-specific membrane antigen (PSMA) expression is high in ACC. We conducted a prospective study to evaluate …
View article: APOE4 modulates the association between DTI‐ALPS index and Alzheimer's pathologies
APOE4 modulates the association between DTI‐ALPS index and Alzheimer's pathologies Open
INTRODUCTION Diffusion‐tensor imaging (DTI) analysis along the perivascular space (ALPS) has emerged as a non‐invasive marker of glymphatic function. Preclinical studies suggest that apolipoprotein E4 ( APOE 4), a major genetic risk factor…
View article: First Real-World Evidence on the Safety and Effectiveness of LutatheraTM for Treating Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs): Insights from Post-Marketing Surveillance
First Real-World Evidence on the Safety and Effectiveness of LutatheraTM for Treating Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs): Insights from Post-Marketing Surveillance Open
Background/Objectives: This post-marketing surveillance study was conducted to evaluate the safety and effectiveness of [177Lu]Lu-DOTA-TATE in patients with GEP-NETs in real-world practice in South Korea. Methods: From July 2020 to July 20…
View article: Table S9 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S9 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S9 shows standardized incidence ratios of cancers with five or more incident cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, using national cancer incidence rates.
View article: Table S2 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S2 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S2 shows standardized prevalence ratios of cancers with fewer than five prevalent cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, Gyeongju, Republic of Korea.
View article: Table S5 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S5 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S5 shows standardized incidence ratios of cancers in relation to proximity to the Wolsong nuclear power plant, stratified by sex.
View article: Table S3 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S3 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S3 shows standardized incidence ratios of cancers with five or more incident cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, after combining Regions I and II.
View article: Data from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Data from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Background:Previous studies on cancer risk near nuclear power plants (NPP) have reported inconsistent results. This study aimed to estimate the standardized incidence ratios (SIR) and standardized prevalence ratios (SPR) of cancer near a N…
View article: Table S4 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S4 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S4 shows standardized prevalence ratios of cancers with five or more prevalent cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, after combining Regions I and II.
View article: Table S8 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S8 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S8 shows standardized incidence ratios of cancers with five or more incident cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, further standardized for income level.
View article: Table S1 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S1 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S1 shows standardized incidence ratios of cancers with fewer than five incident cases in each distant stratum in relation to proximity to the Wolsong nuclear power plant, Gyeongju, Republic of Korea.
View article: Table S6 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S6 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S6 shows standardized prevalence ratios of cancers in relation to proximity to the Wolsong nuclear power plant, stratified by sex.
View article: Table S7 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea
Table S7 from Cancer Incidence and Prevalence in Relation to Proximity to a Nuclear Power Plant in Gyeongju, Republic of Korea Open
Supplementary Table S7 shows standardized incidence and prevalence ratios of all cancers among individuals under 20 years of age, in relation to proximity to the Wolsong nuclear power plant.
View article: Blood-based transcriptomic biomarkers for response to [177Lu]Lu-DOTA-TATE therapy in neuroendocrine tumors
Blood-based transcriptomic biomarkers for response to [177Lu]Lu-DOTA-TATE therapy in neuroendocrine tumors Open
Background [ 177 Lu]Lu-DOTA-TATE is an effective treatment for metastatic neuroendocrine tumors (NETs) expressing somatostatin receptors. While the tumor uptake [ 177 Lu]Lu-DOTA-TATE of has shown potential as a predictive biomarker, patien…
View article: High cereblon expression in neuroendocrine cancer confers vulnerability to GSPT1 molecular glue degrader
High cereblon expression in neuroendocrine cancer confers vulnerability to GSPT1 molecular glue degrader Open
Background Recent advances in targeted therapies have introduced molecular glue degraders (MGDs) that leverage the cereblon (CRBN) E3 ubiquitin ligase to degrade the translation termination factor GSPT1. Understanding the cellular context …
View article: Revealing the role of increased SK3 expression in sulfonylurea resistance triggered by prolonged exposure
Revealing the role of increased SK3 expression in sulfonylurea resistance triggered by prolonged exposure Open
This study elucidates the molecular mechanisms underlying SR, with a specific focus on the overexpression of the SK3 channel in insulinoma cells. These findings enhance our understanding of the challenges associated with prolonged sulfonyl…
View article: 321 | GLOFITAMAB, POSELTINIB AND LENALIDOMIDE FOR PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B CELL LYMPHOMA
321 | GLOFITAMAB, POSELTINIB AND LENALIDOMIDE FOR PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B CELL LYMPHOMA Open
View article: Deep Learning-Based Similar Image Retrieval Method Using Triplet Sampling Strategy and HNSW Algorithm
Deep Learning-Based Similar Image Retrieval Method Using Triplet Sampling Strategy and HNSW Algorithm Open
View article: Therapeutic potential of FAPI RLT in oncology: A systematic review
Therapeutic potential of FAPI RLT in oncology: A systematic review Open
Rationale: This systematic review aims to examine the safety and efficacy of fibroblast activation protein inhibitor (FAPI) radioligand therapy (RLT) for various epithelial neoplasms. Methods: PubMed, Web of Science, and Scop…
View article: Dickkopf-1 promotes tumor progression of gefitinib- resistant non-small cell lung cancer through cancer cell-fibroblast interactions
Dickkopf-1 promotes tumor progression of gefitinib- resistant non-small cell lung cancer through cancer cell-fibroblast interactions Open
View article: The Use of Antihypertensive Medication and <scp><i>In Vivo</i></scp> Alzheimer's Disease Pathology
The Use of Antihypertensive Medication and <span><i>In Vivo</i></span> Alzheimer's Disease Pathology Open
Objective We investigated whether the use of antihypertensive medication (AHM) is associated with in vivo Alzheimer's Disease (AD) pathologies in older adults with hypertension and examined if the effect differs by drug‐class and blood–bra…
View article: Provocation
Provocation Open
View article: Radiation-induced exosomal miR-21 enhances tumor proliferation and invasiveness in breast cancer: implications for poor prognosis in radiotherapy patients
Radiation-induced exosomal miR-21 enhances tumor proliferation and invasiveness in breast cancer: implications for poor prognosis in radiotherapy patients Open
View article: Telomere length, in vivo Alzheimer’s disease pathologies and cognitive decline in older adults
Telomere length, in vivo Alzheimer’s disease pathologies and cognitive decline in older adults Open
Background Whether telomere length (TL), an indicator of biological ageing, reflects Alzheimer’s disease (AD)-related neuropathological change remains unclear. We investigated the relationships between TL, in vivo AD pathologies, including…
View article: Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors Open
Background: Radiotherapy is a widely employed technique for eradication of tumor using high-energy beams, and has been applied to approximately 50% of all solid tumor patients. However, its non-specific, cell-killing property leads …
View article: PolyPal: A parallel microscale virtual specimen generator
PolyPal: A parallel microscale virtual specimen generator Open
View article: Enhancing voxel‐based dosimetry accuracy with an unsupervised deep learning approach for hybrid medical image registration
Enhancing voxel‐based dosimetry accuracy with an unsupervised deep learning approach for hybrid medical image registration Open
Background Deformable registration is required to generate a time‐integrated activity (TIA) map which is essential for voxel‐based dosimetry. The conventional iterative registration algorithm using anatomical images (e.g., computed tomogra…
View article: Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK-inhibitors
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK-inhibitors Open
Radiotherapy is a widely employed technique for eradication of tumor using high-energy beams, and has been applied to approximately 50% of all solid tumor patients. However, its non-specific, cell-killing property leads to inevitable damag…
View article: siRNA treatment targeting integrin α11 overexpressed via EZH2-driven axis inhibits drug-resistant breast cancer progression
siRNA treatment targeting integrin α11 overexpressed via EZH2-driven axis inhibits drug-resistant breast cancer progression Open
Background Breast cancer, the most prevalent cancer in women worldwide, faces treatment challenges due to drug resistance, posing a serious threat to patient survival. The present study aimed to identify the key molecules that drive drug r…