Kerri L. LaRovere
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View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data Open
View article: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Outcomes and Endpoints
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Outcomes and Endpoints Open
The DoC outcome and endpoint CDEs are a starting point in the broader effort to standardize outcome evaluation of persons with DoC. The ultimate goal is to harmonize DoC studies and allow for more precise assessment of outcomes after sever…
View article: MRI and Clinical Variables for Prediction of Outcomes After Pediatric Severe Traumatic Brain Injury
MRI and Clinical Variables for Prediction of Outcomes After Pediatric Severe Traumatic Brain Injury Open
Importance Traumatic brain injury (TBI) is a leading cause of death and disability in children, and predicting functional outcome after TBI is challenging. Magnetic resonance imaging (MRI) is frequently conducted after severe TBI; however,…
View article: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population Open
Background The fundamental gap obstructing forward progress of evidenced based care in pediatric and neonatal disorders of consciousness (DoC) is the lack of defining consensus-based terminology to perform comparative research. This lack o…
View article: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data Open
View article: Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process*
Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process* Open
OBJECTIVES: To address areas in which there is no consensus for the technologies, effort, and training necessary to integrate and interpret information from multimodality neuromonitoring (MNM). DESIGN: A three-round Delphi consensus proces…
View article: Utility of Exome Sequencing for Diagnosis in Unexplained Pediatric-Onset Epilepsy
Utility of Exome Sequencing for Diagnosis in Unexplained Pediatric-Onset Epilepsy Open
Importance Genomic advances inform our understanding of epilepsy and can be translated to patients as precision diagnoses that influence clinical treatment, prognosis, and counseling. Objective To delineate the genetic landscape of pediatr…
View article: Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury
Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury Open
IMPORTANCE: Bedside measurement of heart rate (HR) change (HRC) may provide an objective physiologic marker for when brain death (BD) may have occurred, and BD testing is indicated in children. OBJECTIVES: To determine whether HRC, calcula…
View article: Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020
Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020 Open
Importance: In 2020 during the COVID-19 pandemic, neurologic involvement was common in children and adolescents hospitalized in the United States for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related complications. Objec…
View article: Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020
Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020 Open
Importance In 2020 during the COVID-19 pandemic, neurologic involvement was common in children and adolescents hospitalized in the United States for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–related complications. Object…
View article: Effectiveness of Training Programs for Reducing Adverse Psychological Outcomes in Parents of Children with Acquired Brain Injury: A Systematic Review and Meta-Analysis
Effectiveness of Training Programs for Reducing Adverse Psychological Outcomes in Parents of Children with Acquired Brain Injury: A Systematic Review and Meta-Analysis Open
View article: Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury
Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury Open
In this comparative effectiveness study, CSF diversion was not associated with improved outcome at 6 months after TBI, but a decrease in ICP was observed. Given the higher quality of evidence generated by this study, current evidence-based…
View article: Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury
Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury Open
In this comparative effectiveness research study, bolus HTS was associated with lower ICP and higher CPP, whereas mannitol was associated only with higher CPP. After adjustment for confounders, both therapies showed no association with ICP…
View article: A Survey of Neuromonitoring Practices in North American Pediatric Intensive Care Units
A Survey of Neuromonitoring Practices in North American Pediatric Intensive Care Units Open
View article: Cerebral Emboli Monitoring Using Transcranial Doppler Ultrasonography in Adults and Children: A Review of the Current Technology and Clinical Applications in the Perioperative and Intensive Care Setting
Cerebral Emboli Monitoring Using Transcranial Doppler Ultrasonography in Adults and Children: A Review of the Current Technology and Clinical Applications in the Perioperative and Intensive Care Setting Open
Transcranial Doppler (TCD) ultrasonography is the only noninvasive bedside technology for the detection and monitoring of cerebral embolism. TCD may identify patients at risk of acute and chronic neurologic injury from gaseous or solid emb…
View article: Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome
Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome Open
In this study, many children and adolescents hospitalized for COVID-19 or multisystem inflammatory syndrome in children had neurologic involvement, mostly transient symptoms. A range of life-threatening and fatal neurologic conditions asso…
View article: Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement
Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement Open
Transcranial Doppler ultrasonography (TCD) is being used in many pediatric intensive care units (PICUs) to aid in the diagnosis and monitoring of children with known or suspected pathophysiological changes to cerebral hemodynamics. Standar…
View article: Fully automated, real-time, calibration-free, continuous noninvasive estimation of intracranial pressure in children
Fully automated, real-time, calibration-free, continuous noninvasive estimation of intracranial pressure in children Open
OBJECTIVE In the search for a reliable, cooperation-independent, noninvasive alternative to invasive intracranial pressure (ICP) monitoring in children, various approaches have been proposed, but at the present time none are capable of pro…
View article: A Time-Frequency Approach for Cerebral Embolic Load Monitoring
A Time-Frequency Approach for Cerebral Embolic Load Monitoring Open
Using only single-channel, single-frequency Doppler ultrasound, the proposed method enables sensitive detection and segmentation of embolic signatures. Our approach paves the way toward accurate real-time cerebral emboli monitoring.