Kerstin Schwenker
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View article: Influence of sports on cortical excitability in patients with spinal cord injury: a TMS study
Influence of sports on cortical excitability in patients with spinal cord injury: a TMS study Open
Background Patients with spinal cord injury (SCI) show abnormal cortical excitability that might be caused by deafferentation. We hypothesize a reduced short-interval intracortical inhibition preceding movement in patients with SCI compare…
View article: Repeated iv <scp>anti‐CD20</scp> treatment in multiple sclerosis: Long‐term effects on peripheral immune cell subsets
Repeated iv <span>anti‐CD20</span> treatment in multiple sclerosis: Long‐term effects on peripheral immune cell subsets Open
Objective Repeated intravenous administration of anti‐CD20 depleting monoclonal antibodies 6 months apart is among the highly effective treatment options in multiple sclerosis (MS). Here, we aimed to investigate peripheral immune cell subs…
View article: Long-term immunological consequences of anti-CD20 therapies on humoral responses to COVID-19 vaccines in multiple sclerosis: an observational study
Long-term immunological consequences of anti-CD20 therapies on humoral responses to COVID-19 vaccines in multiple sclerosis: an observational study Open
Background: Anti-CD20 therapies induce pronounced B-cell depletion and blunt humoral responses to vaccines. Recovery kinetics of anti-CD20 therapy-mediated cellular and humoral effects in people with multiple sclerosis (pwMS) are poorly de…
View article: Cladribine Alters Immune Cell Surface Molecules for Adhesion and Costimulation: Further Insights to the Mode of Action in Multiple Sclerosis
Cladribine Alters Immune Cell Surface Molecules for Adhesion and Costimulation: Further Insights to the Mode of Action in Multiple Sclerosis Open
Cladribine (CLAD) is a deoxyadenosine analogue prodrug which is given in multiple sclerosis (MS) as two short oral treatment courses 12 months apart. Reconstitution of adaptive immune function following selective immune cell depletion is t…
View article: Tetravalent Influenza Vaccine Is Not Associated With Neuroaxonal Damage in Multiple Sclerosis Patients
Tetravalent Influenza Vaccine Is Not Associated With Neuroaxonal Damage in Multiple Sclerosis Patients Open
Background Efficacy of vaccines and disease activity linked to immunization are major concerns among people with multiple sclerosis (pwMS). Objective To assess antibody responses to seasonal influenza antigens and vaccine-associated neuroa…
View article: Narrative Review: Quantitative EEG in Disorders of Consciousness
Narrative Review: Quantitative EEG in Disorders of Consciousness Open
In this narrative review, we focus on the role of quantitative EEG technology in the diagnosis and prognosis of patients with unresponsive wakefulness syndrome and minimally conscious state. This paper is divided into two main parts, i.e.,…
View article: Long‐term peripheral immune cell profiling reveals further targets of oral cladribine in MS
Long‐term peripheral immune cell profiling reveals further targets of oral cladribine in MS Open
Objectives To expand the knowledge about the immunological consequences of cladribine (CLAD), a pulsed immune reconstitution therapy approved for active multiple sclerosis (MS), beyond the known short‐term effects on peripheral immune cell…
View article: Functional Magnetic Resonance Imaging in the Final Stage of Creutzfeldt-Jakob Disease
Functional Magnetic Resonance Imaging in the Final Stage of Creutzfeldt-Jakob Disease Open
Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare fatal degenerative disease of the central nervous system. The clinical course is characterized by rapid progression of neurological and neuromuscular symptoms. The late stage with loss of…
View article: Vitamin D Supplementation in Multiple Sclerosis: A Critical Analysis of Potentials and Threats
Vitamin D Supplementation in Multiple Sclerosis: A Critical Analysis of Potentials and Threats Open
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS). In recent years, vitamin D has gained attention, as low serum levels are suspected to increase the risk for …
View article: Facilitation of Auditory Comprehension After Theta Burst Stimulation of Wernicke's Area in Stroke Patients: A Pilot Study
Facilitation of Auditory Comprehension After Theta Burst Stimulation of Wernicke's Area in Stroke Patients: A Pilot Study Open
Introduction: Single-pulse transcranial magnetic stimulation (TMS) and high-frequency repetitive TMS (rTMS) over Wernicke's area were found to facilitate language functions in right-handed healthy subjects. We aimed at investigating the ef…
View article: Cholinergic transmission is impaired in patients with idiopathic normal-pressure hydrocephalus: a TMS study
Cholinergic transmission is impaired in patients with idiopathic normal-pressure hydrocephalus: a TMS study Open
The pathophysiological mechanisms of cognitive and gait disturbances in subjects with normal-pressure hydrocephalus (NPH) are still unclear. Cholinergic and other neurotransmitter abnormalities have been reported in animal models of NPH. T…
View article: Spinal cord involvement in Lewy body-related α-synucleinopathies
Spinal cord involvement in Lewy body-related α-synucleinopathies Open
Context: Lewy body (LB)-related α-synucleinopathy (LBAS) is the neuropathological hallmark of several neurodegenerative diseases such as Parkinson disease (PD), but it is also found in neurologically asymptomatic subjects. An abnorm…
View article: rTMS of the prefrontal cortex has analgesic effects on neuropathic pain in subjects with spinal cord injury
rTMS of the prefrontal cortex has analgesic effects on neuropathic pain in subjects with spinal cord injury Open