Nicholas A Kerna
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View article: From Data to Deployment: Guiding Onsite Naturopathic Care Unit Preparation and Response Through Injury Analytics from a High-Volume Team-Based Court Sport Tournament
From Data to Deployment: Guiding Onsite Naturopathic Care Unit Preparation and Response Through Injury Analytics from a High-Volume Team-Based Court Sport Tournament Open
Background: The Emerald City Volleyball Classic is an annual tournament involving over 1,000 amateur female youth athletes. Since 2010, a medical team composed of licensed naturopathic physicians and student clinicians from Integrative Med…
View article: Bridging the Gap: Examining Innovative and Sustainable Solutions for Addressing Rural Healthcare Disparities
Bridging the Gap: Examining Innovative and Sustainable Solutions for Addressing Rural Healthcare Disparities Open
This paper examines fundamental and innovative solutions for improving and sustaining efforts to address rural healthcare disparities in the United States. As a foundation for these solutions, it also examines the persistent healthcare dis…
View article: An Observational Pilot Study of Compliance with a Naturopathic Concussion Protocol in Female Youth Volleyball Athletes and Return-to-Play Time
An Observational Pilot Study of Compliance with a Naturopathic Concussion Protocol in Female Youth Volleyball Athletes and Return-to-Play Time Open
Purpose: Concussions are a form of traumatic brain injury frequently observed in youth sports, with variable recovery patterns. Integrative medicine, including naturopathic care, has gained interest as a supportive approach, though limited…
View article: Current Applications of Artificial Intelligence in Reproductive Medicine (and Predominant OB/GYN and Andrologic Conditions)
Current Applications of Artificial Intelligence in Reproductive Medicine (and Predominant OB/GYN and Andrologic Conditions) Open
Artificial intelligence (AI) has increasingly permeated clinical domains, including reproductive medicine, where its applications span from gamete assessment to population-level epidemiology. The convergence of machine learning, deep learn…
View article: Current Applications of Artificial Intelligence in Psychiatry
Current Applications of Artificial Intelligence in Psychiatry Open
The integration of artificial intelligence (AI) into psychiatric practice has accelerated rapidly, driven by advances in computational methods and the availability of diverse data sources. The present paper examines contemporary AI applica…
View article: Obesity and Cancer: Excess Body Fat as a Risk Factor in Carcinogenesis; Consequences Across Human Body Systems and Significance for Associated Medical Specialties
Obesity and Cancer: Excess Body Fat as a Risk Factor in Carcinogenesis; Consequences Across Human Body Systems and Significance for Associated Medical Specialties Open
Obesity is a known risk factor for various cancers, influencing carcinogenesis through metabolic, hormonal, and inflammatory pathways. Excess adiposity leads to insulin resistance, chronic inflammation, and hormonal imbalances, all of whic…
View article: PFAS Exposure and Kidney Health with Gut Microbiota, Blood Metabolites, and Multi-Organ Implications Across Medical Specialties
PFAS Exposure and Kidney Health with Gut Microbiota, Blood Metabolites, and Multi-Organ Implications Across Medical Specialties Open
PFAS (per- and polyfluoroalkyl substances) exposure has been linked to kidney damage through mechanisms involving gut microbiota dysbiosis and alterations in blood metabolites. These disruptions trigger renal inflammation, oxidative stress…
View article: UPFs and Shortened Lifespans: Ultra-Processed Foods Linked to Accelerated Biological Aging; Consequences Across Human Body Systems and Implications for Associated Medical Specialties
UPFs and Shortened Lifespans: Ultra-Processed Foods Linked to Accelerated Biological Aging; Consequences Across Human Body Systems and Implications for Associated Medical Specialties Open
Ultra-processed foods (UPFs) are defined by their high levels of refined carbohydrates, unhealthy fats, artificial additives, and preservatives. These foods contribute to biological aging through mechanisms such as chronic inflammation, ox…
View article: Current Applications of Artificial Intelligence in Internal Medicine
Current Applications of Artificial Intelligence in Internal Medicine Open
This paper presents a comprehensive overview of the current applications of artificial intelligence (AI) in internal medicine, highlighting its transformative potential in improving diagnostics, treatment and management, prognostication, a…
View article: Addressing the Underutilization of Electrodiagnostic and Electrotherapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization
Addressing the Underutilization of Electrodiagnostic and Electrotherapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization Open
The underutilization of electrodiagnostic and electrotherapeutic tools has far-reaching consequences, impacting diagnostic accuracy, treatment outcomes, healthcare costs, and patient satisfaction. These issues are often rooted in inadequat…
View article: Beyond Medication: The Impact of Physical Activity and Herbal Options in Managing Depression
Beyond Medication: The Impact of Physical Activity and Herbal Options in Managing Depression Open
Physical activity has been gaining recognition as a key component in managing depression, with its physiological, biochemical, and neurological effects playing a crucial role in improving mental health. Exercise enhances neuroplasticity, p…
View article: Addressing the Underutilization of Electrodiagnostic and Electrotherapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization
Addressing the Underutilization of Electrodiagnostic and Electrotherapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization Open
View article: The Gut-Brain Axis in Neurodevelopmental Disorders: Mechanistic Insights, Clinical Implications, and Public Health Strategies
The Gut-Brain Axis in Neurodevelopmental Disorders: Mechanistic Insights, Clinical Implications, and Public Health Strategies Open
View article: Addressing the Underutilization of Electrodiagnostic and Electro-Therapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization
Addressing the Underutilization of Electrodiagnostic and Electro-Therapeutic Tools in Clinical Practice: Optimizing Clinical Outcomes and Operational Viability Through Enhanced Utilization Open
View article: Impact of Medication Nonadherence Across Medical Specialties: Effects on Clinical Outcomes, Physician Satisfaction, and Socioeconomic Factors with Tools for Mitigation
Impact of Medication Nonadherence Across Medical Specialties: Effects on Clinical Outcomes, Physician Satisfaction, and Socioeconomic Factors with Tools for Mitigation Open
View article: The Gut-Brain Axis in Neurodevelopmental Disorders: Mechanistic Insights, Clinical Implications, and Public Health Strategies
The Gut-Brain Axis in Neurodevelopmental Disorders: Mechanistic Insights, Clinical Implications, and Public Health Strategies Open
The integration of gut microbiota research into the understanding and treatment of neurodevelopmental disorders has profound implications for both clinical practice and public health. The microbial community’s influence on neural developme…
View article: Impact of Medication Nonadherence Across Medical Specialties: Effects on Clinical Outcomes, Physician Satisfaction, and Socioeconomic Factors with Tools for Mitigation
Impact of Medication Nonadherence Across Medical Specialties: Effects on Clinical Outcomes, Physician Satisfaction, and Socioeconomic Factors with Tools for Mitigation Open
Nonadherence to prescribed medications is a significant issue across many medical specialties and human conditions. Nonadherence affects individuals with chronic diseases like cardiovascular disease, diabetes, hypertension, psychiatric dis…
View article: Optimizing Major Depression Management by Integrating Physical Activity and Targeted Lifestyle Changes
Optimizing Major Depression Management by Integrating Physical Activity and Targeted Lifestyle Changes Open
View article: St. John’s Wort (Hypericum perforatum) in Major Depressive Disorder: Efficacy, Safety, Clinical Implications, and Its Role as an Herbal Alternative or Complementary Treatment
St. John’s Wort (Hypericum perforatum) in Major Depressive Disorder: Efficacy, Safety, Clinical Implications, and Its Role as an Herbal Alternative or Complementary Treatment Open
View article: Optimizing Major Depression Management by Integrating Physical Activity and Targeted Lifestyle Changes
Optimizing Major Depression Management by Integrating Physical Activity and Targeted Lifestyle Changes Open
View article: St. John’s Wort (Hypericum perforatum) in Major Depressive Disorder: Efficacy, Safety, Clinical Implications, and Its Role as an Herbal Alternative or Complementary Treatment
St. John’s Wort (Hypericum perforatum) in Major Depressive Disorder: Efficacy, Safety, Clinical Implications, and Its Role as an Herbal Alternative or Complementary Treatment Open
View article: Balancing Placebo Use with Evidence-Based Treatments: The Placebo Effect in Clinical Practice and Research
Balancing Placebo Use with Evidence-Based Treatments: The Placebo Effect in Clinical Practice and Research Open
The placebo effect has notable implications for clinical practice and research, demonstrating its ability to enhance therapeutic outcomes through psychological and physiological mechanisms. Evidence shows that placebos can impact treatment…
View article: Hematological Conditions Associated with COVID-19: Pathophysiology, Clinical Manifestations, and Therapeutic Approaches
Hematological Conditions Associated with COVID-19: Pathophysiology, Clinical Manifestations, and Therapeutic Approaches Open
This review highlights the significant impact of SARS-CoV-2 on the hematological system, revealing complications such as thrombocytopenia, coagulopathy, venous thromboembolism (VTE), and hemolytic anemia, which contribute notably to morbid…
View article: Transformative Advancements in Diagnostic Imaging: Reducing Risks, Enhancing Accuracy, and Promoting Sustainability
Transformative Advancements in Diagnostic Imaging: Reducing Risks, Enhancing Accuracy, and Promoting Sustainability Open
The review discusses the risks posed by conventional medical imaging methods, including radiation exposure, allergic reactions, and environmental contamination. It explores recent innovations, such as advanced modalities like photon-counti…
View article: Impact of Detox Diets on Obesity and Metabolic Syndrome: Implications for Weight Loss, Metabolic Health, and Clinical Practice
Impact of Detox Diets on Obesity and Metabolic Syndrome: Implications for Weight Loss, Metabolic Health, and Clinical Practice Open
Detox diets, including intermittent fasting, ketogenic, Paleo, vegetarian, Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Whole30, are notable strategies for managing obesity and metabolic syndrome. This review evaluate…
View article: Current Strategies and Future Directions in Multiple Myeloma: Disease Overview and Pathophysiology, Conventional Treatments and Emerging Therapies, Challenges and Innovations in Management
Current Strategies and Future Directions in Multiple Myeloma: Disease Overview and Pathophysiology, Conventional Treatments and Emerging Therapies, Challenges and Innovations in Management Open
The review examines multiple myeloma, including pathophysiology, conventional treatments, current management strategies, treatment challenges, and emerging therapies. The disease, originating from malignant plasma cells, leads to bone marr…
View article: Mental Health in Later Life: Clinical Insights and Management Strategies for Late-Onset Psychiatric Conditions
Mental Health in Later Life: Clinical Insights and Management Strategies for Late-Onset Psychiatric Conditions Open
Late-onset psychiatric conditions, which emerge or are first diagnosed in older adulthood, present unique challenges. This review examines their prevalence, risk factors, and clinical presentations, providing a comprehensive overview of th…
View article: Heavy Metals and Human Health: From Neurological Disorders to Developmental Delays
Heavy Metals and Human Health: From Neurological Disorders to Developmental Delays Open
This review discusses the significant health risks posed by exposure to environmentally toxic heavy metals such as lead, mercury, cadmium, arsenic, chromium, and nickel. These metals can cause severe and sometimes irreversible damage to va…
View article: Cellular Pathophysiology in Zoonotic Transmission of Orthopoxviruses (OPXVs) from Animal Host to Human
Cellular Pathophysiology in Zoonotic Transmission of Orthopoxviruses (OPXVs) from Animal Host to Human Open
Orthopoxviruses (OPXVs), belonging to the Poxviridae family, are large, double-stranded DNA viruses known for their zoonotic potential and impact on human and animal health. This review explores the transmission dynamics of OPXVs from anim…
View article: The Multisystem Impact of Pseudoxanthoma Elasticum (PXE): Systemic Manifestations, Multidisciplinary Management, and Diagnostic and Therapeutic Advances
The Multisystem Impact of Pseudoxanthoma Elasticum (PXE): Systemic Manifestations, Multidisciplinary Management, and Diagnostic and Therapeutic Advances Open
The review discusses pseudoxanthoma elasticum (PXE) as a multisystem disorder with diverse manifestations across dermatological, ophthalmological, and cardiovascular systems. It covers the primary dermatological signs, such as yellowish pa…