Kevin E. Woods
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View article: Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS
Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS Open
Somatic mutations in hematopoietic stem/progenitor cells (HSPCs) can lead to clonal hematopoiesis of indeterminate potential (CHIP), potentially progressing to myelodysplastic syndromes (MDS). Here, we investigated how CHIP and MDS remodel…
View article: Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer Open
Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchym…
View article: Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche Open
View article: First interobserver agreement of optical coherence tomography in the bile duct: A multicenter collaborative study
First interobserver agreement of optical coherence tomography in the bile duct: A multicenter collaborative study Open
Background and study aims Optical coherence tomography (OCT) is a new technology available for evaluation of indeterminate biliary strictures. It allows under-the-surface visualization and preliminary studies have confirmed standardized ch…
View article: Short-term aspirin and statin chemoprophylaxis did not reduce the risk of developing advanced adenomatous polyps in Black patients
Short-term aspirin and statin chemoprophylaxis did not reduce the risk of developing advanced adenomatous polyps in Black patients Open
Background Chemoprevention of colorectal neoplasia with aspirin and statins is under-investigated in Black patients. Since Black patients suffer disproportionately from colon cancer incidence and mortality compared to other populations, we…
View article: Dynamic Changes of the Bone Marrow Niche: Mesenchymal Stromal Cells and Their Progeny During Aging and Leukemia
Dynamic Changes of the Bone Marrow Niche: Mesenchymal Stromal Cells and Their Progeny During Aging and Leukemia Open
Mesenchymal stromal cells (MSCs) are a heterogenous cell population found in a wide range of tissues in the body, known for their nutrient-producing and immunomodulatory functions. In the bone marrow (BM), these MSCs are critical for the r…
View article: Su1517 FIRST INTEROBSERVER AGREEMENT OF OPTICAL COHERENCE TOMOGRAPHY IN THE BILE DUCT: A MULTICENTER COLLABORATIVE STUDY
Su1517 FIRST INTEROBSERVER AGREEMENT OF OPTICAL COHERENCE TOMOGRAPHY IN THE BILE DUCT: A MULTICENTER COLLABORATIVE STUDY Open
View article: Pancreatic Insufficiency Secondary to Tobacco Exposure
Pancreatic Insufficiency Secondary to Tobacco Exposure Open
This study suggests that tobacco exposure is independently associated with pancreatic exocrine insufficiency in patients without a prior diagnosis of pancreatic disease. Tobacco exposure seems to have greater detrimental effects on pancrea…
View article: Treatment allocation in patients with early‐stage esophageal adenocarcinoma: Prevalence and predictors of lymph node involvement
Treatment allocation in patients with early‐stage esophageal adenocarcinoma: Prevalence and predictors of lymph node involvement Open
BACKGROUND In considering treatment allocation for patients with early esophageal adenocarcinoma, the incidence of lymph node metastasis is a critical determinant; however, this has not been well defined or stratified by the relevant clini…
View article: Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients
Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients Open
White light colonoscopy is the current gold standard for early detection and treatment of colorectal cancer, but emerging data suggest that this approach is inherently limited. Even the most experienced colonoscopists, under optimal condit…
View article: Triple modality testing by endoscopic retrograde cholangiopancreatography for the diagnosis of cholangiocarcinoma
Triple modality testing by endoscopic retrograde cholangiopancreatography for the diagnosis of cholangiocarcinoma Open
Objectives: Brush cytology has a low sensitivity for the diagnosis of cholangiocarcinoma. This study aimed to compare the standard approach (brush cytology) with a triple modality approach utilizing brush cytology, forceps biopsy and fluor…