Gang Han
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Symptom Severity Profiles and their Associated Factors in Minoritized Men with Chronic Conditions Open
Individuals with chronic conditions have persistent, co-occurring symptoms affecting quality of life. Understanding symptom severity susceptibilities is critical for early risk identification, but gaps remain among racial and ethnic minori…
View article: Anatomizing Resilience: The Multi-Dimensional Evolution and Drivers of Regional Collaborative Innovation Networks
Anatomizing Resilience: The Multi-Dimensional Evolution and Drivers of Regional Collaborative Innovation Networks Open
In an era of intensifying global technological competition and systemic disruptions, the resilience of metropolitan innovation networks has emerged as a cornerstone of sustainable regional development. Based on joint invention patents, thi…
View article: Colon Enzyme‐Activated Prebiotic Nanomedicine for Targeted Therapy of Inflammatory Bowel Disease
Colon Enzyme‐Activated Prebiotic Nanomedicine for Targeted Therapy of Inflammatory Bowel Disease Open
Inflammatory bowel disease is commonly treated with conventional therapies that suffer from poor drug bioavailability and significant side effects. This work develops a nanoparticle system using inulin, a naturally occurring polysaccharide…
View article: Perceived Discrimination in Medical Care Settings on A1c Data From the <i>All of Us</i> Program
Perceived Discrimination in Medical Care Settings on A1c Data From the <i>All of Us</i> Program Open
Approximately 11.3% of the U.S. population has diabetes, mostly type 2 diabetes (T2DM), and maintenance of A1c levels is vital to prevent complications among patients. Perceived discrimination in medical care settings (PDMS) affects patien…
View article: Occupancy World Model for Robots
Occupancy World Model for Robots Open
Understanding and forecasting the scene evolutions deeply affect the exploration and decision of embodied agents. While traditional methods simulate scene evolutions through trajectory prediction of potential instances, current works use t…
View article: Persistent Poverty, Rural Location, and Racial Segregation are Factors in Colorectal Cancer Screening in Low-Income and Uninsured Populations
Persistent Poverty, Rural Location, and Racial Segregation are Factors in Colorectal Cancer Screening in Low-Income and Uninsured Populations Open
Purpose: This study aimed to investigate the correlation between geographical factors, including rurality, persistent poverty counties, racial residential segregation, and adherence to colorectal cancer (CRC) screening among low-income uni…
View article: LiPS: Large-Scale Humanoid Robot Reinforcement Learning with Parallel-Series Structures
LiPS: Large-Scale Humanoid Robot Reinforcement Learning with Parallel-Series Structures Open
In recent years, research on humanoid robots has garnered significant attention, particularly in reinforcement learning based control algorithms, which have achieved major breakthroughs. Compared to traditional model-based control algorith…
View article: Heterogeneous Activation of NaClO by Nano-CoMn2O4 Spinel for Methylene Blue Decolorization
Heterogeneous Activation of NaClO by Nano-CoMn2O4 Spinel for Methylene Blue Decolorization Open
In this study, the nano-spinel CoMn2O4 was synthesized by coprecipitation pyrolysis and employed to heterogeneously activate hypochlorite (NaClO) for the oxidative decolorization of methylene blue (MB). The crystal structure, elemental com…
View article: In Situ Slow‐Release Hydrogen Sulfide Therapeutics for Advanced Disease Treatments
In Situ Slow‐Release Hydrogen Sulfide Therapeutics for Advanced Disease Treatments Open
Hydrogen sulfide (H 2 S) gas therapygarners significant attention for its potential to improve outcomes in various disease treatments. The quantitative control of H 2 S release is crucial for effective the rapeutic interventions; however, …
View article: Controlled Inflammation Drives Neutrophil‐Mediated Precision Drug Delivery in Heterogeneous Tumors
Controlled Inflammation Drives Neutrophil‐Mediated Precision Drug Delivery in Heterogeneous Tumors Open
Tumor heterogeneity remains a formidable obstacle in targeted cancer therapy, often leading to suboptimal treatment outcomes. This study presents an innovative approach that harnesses controlled inflammation to guide neutrophil‐mediated dr…
View article: Study of the Effect of Temperature and Microwave Action on the Structure of Polyvinyl Alcohol (PVA)
Study of the Effect of Temperature and Microwave Action on the Structure of Polyvinyl Alcohol (PVA) Open
Polyvinyl alcohol (PVA) is a widely utilized molecular polymer characterized by its strong water solubility, chemical resistance, and mechanical properties. Notably, it possesses the capability for biodegradation and finds extensive applic…
View article: Research on the Income Guarantee of Grain Farmers from the Perspective of Food Security
Research on the Income Guarantee of Grain Farmers from the Perspective of Food Security Open
Food security is an important foundation for national security, and ensuring the income of grain farmers is a key link in solving food security issues. This article explores in depth the construction and improvement of the income guarantee…
View article: E2H: A Two-Stage Non-Invasive Neural Signal Driven Humanoid Robotic Whole-Body Control Framework
E2H: A Two-Stage Non-Invasive Neural Signal Driven Humanoid Robotic Whole-Body Control Framework Open
Recent advancements in humanoid robotics, including the integration of hierarchical reinforcement learning-based control and the utilization of LLM planning, have significantly enhanced the ability of robots to perform complex tasks. In co…
View article: Adequacy of the Dosing and Infusion Time of Ceftazidime/Avibactam for the Treatment of Gram-Negative Bacterial Infections: A PK/PD Simulation Study
Adequacy of the Dosing and Infusion Time of Ceftazidime/Avibactam for the Treatment of Gram-Negative Bacterial Infections: A PK/PD Simulation Study Open
The current recommended dosing regimen of ceftazidime/avibactam is insufficient for severe infection patients, and continuous infusion is suggested.
View article: Spatiotemporal Dynamics and Mainstreaming Strategies of Ecosystem-Based Adaptation to Urban Climate Change
Spatiotemporal Dynamics and Mainstreaming Strategies of Ecosystem-Based Adaptation to Urban Climate Change Open
Cities worldwide are facing varying degrees of ongoing threats closely tied to climate change. Research is emerging that addresses climate risks as a pressing issue, especially for vulnerable cities in the Global South; however, there is a…
View article: X-ray-activated polymerization expanding the frontiers of deep-tissue hydrogel formation
X-ray-activated polymerization expanding the frontiers of deep-tissue hydrogel formation Open
Photo-crosslinking polymerization stands as a fundamental pillar in the domains of chemistry, biology, and medicine. Yet, prevailing strategies heavily rely on ultraviolet/visible (UV/Vis) light to elicit in situ crosslinking. The inherent…
View article: Factors Associated with Abnormal Mammogram Results Among Low-Income Uninsured Populations in Medically Underserved And Rural Texas Regions
Factors Associated with Abnormal Mammogram Results Among Low-Income Uninsured Populations in Medically Underserved And Rural Texas Regions Open
This study found a significant correlation between area-level educational characteristics and abnormal mammography outcomes. Future research should explore the contextual risk factors influencing breast cancer occurrence and develop target…
View article: Advances in functionalized annihilators to extend triplet–triplet annihilation upconversion performances
Advances in functionalized annihilators to extend triplet–triplet annihilation upconversion performances Open
Triplet–triplet annihilation upconversion (TTA-UC) has made major advances in many emerging fields in recent years, such as solar light harvesting, photocatalysis, biological imaging, and sensing. TTA-UC consists of photosensitizers and an…
View article: Enhancing Osteosacoma Killing and CT Imaging Using Ultra High Drug Loading and NIR‐Responsive Bismuth Sulfide @Mesoporous Silica Nanoparticles
Enhancing Osteosacoma Killing and CT Imaging Using Ultra High Drug Loading and NIR‐Responsive Bismuth Sulfide @Mesoporous Silica Nanoparticles Open
In the original version of this article, there was a mistake in Figure 7c due to errors during the compilation of the images. The correct figure is shown below. This mistake does not affect the results, discussions and conclusions publishe…
View article: Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis
Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis Open
Background: Vancomycin dosing is difficult in critically ill patients receiving continuous renal replacement therapy (CRRT). Previous population pharmacokinetic (PopPK) models seldom consider the effect of residual diuresis, a significant …
View article: Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations
Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations Open
The liver is one of the key organs for exogenous and endogenous metabolism and is often a target for drug- and chemical-driven toxicity. A wide range of experimental approaches has been established to model and characterize the mechanisms …
View article: Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for <i>in vitro</i> studies of drug transport and toxicity
Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for <i>in vitro</i> studies of drug transport and toxicity Open
Microphysiological systems are an emerging area of in vitro drug development, and their independent evaluation is important for wide adoption and use. The primary goal of this study was to test reproducibility and robustness of a renal pro…
View article: GeAs as an emerging p-type van der Waals semiconductor and its application in p–n photodiodes
GeAs as an emerging p-type van der Waals semiconductor and its application in p–n photodiodes Open
van der Waals (vdW) layered materials have shown great potential for future optoelectronic applications owing to their unique and variable properties. In particular, two-dimensional layered materials enable the creation of various circuita…
View article: An accurate equivalence method of distribution system for transmission system operational reliability assessment
An accurate equivalence method of distribution system for transmission system operational reliability assessment Open
In the modern power system, the uncertainty on the power supply and electrical load will aggravate the volatility in the transmission system. Therefore, the accurate operational reliability evaluation of the transmission system is very imp…
View article: Supplementary Data from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone
Supplementary Data from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone Open
Supplementary Data - PDF file 126K, Supplementary Figure S1. The isolation and culture of MNGCs and SCs from GCTB samples. A. After a quick centrifuge, the raw MNGCs were stained with Hoechst 33342 for 1h and sorted by a flow cytometric ce…
View article: Supplementary Data Legends from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone
Supplementary Data Legends from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone Open
Supplementary Data Legends - PDF file 57K, Figure legends for supplementary data
View article: Data from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone
Data from IL-17A Stimulates the Progression of Giant Cell Tumors of Bone Open
Purpose: Giant cell tumors of bone (GCTB) exhibit aggressive bone lytic behavior. Studies have shown that interleukin 17A (IL-17A) is involved pathologic bone resorption in various skeletal disorders. Thus, we have investigated the role of…