Kevin Hansen
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View article: Expression patterns of TROP2 and Nectin-4 in oropharyngeal squamous cell carcinoma in relation to HPV status: potential biomarkers for targeted therapy
Expression patterns of TROP2 and Nectin-4 in oropharyngeal squamous cell carcinoma in relation to HPV status: potential biomarkers for targeted therapy Open
Background: Patients with inoperable or metastatic oropharyngeal squamous cell carcinoma (OSCC) face limited therapeutic options. Nectin-4, an immunoglobulin-like transmembrane adhesion protein, and Trophoblast Surface Antigen 2 (TROP2), a…
View article: Local T-Cell Dysregulation and Immune Checkpoint Expression in Human Papillomavirus-Mediated Recurrent Respiratory Papillomatosis
Local T-Cell Dysregulation and Immune Checkpoint Expression in Human Papillomavirus-Mediated Recurrent Respiratory Papillomatosis Open
Human papillomavirus-mediated recurrent respiratory papillomatosis (RRP) is a premalignant neoplasia of the upper airway characterized by significant dysphonia and respiratory obstruction. Immune checkpoint blockade has emerged as a potent…
View article: Stakeholder perspectives on implementation of internet-delivered cognitive behaviour therapy in physical medicine rehabilitation setting using the Consolidated Framework for Implementation Research
Stakeholder perspectives on implementation of internet-delivered cognitive behaviour therapy in physical medicine rehabilitation setting using the Consolidated Framework for Implementation Research Open
Introduction: Despite the growing evidence for the effects of tailored internet-delivered cognitive behaviour therapy (ICBT) programmes for those receiving physical rehabilitation, there is a lack of implementation of these programmes in a…
View article: Analysis of the Quality of Septoplasty Videos on YouTube and Validation of the IVORY-Grading-System Quality of Septoplasty Videos
Analysis of the Quality of Septoplasty Videos on YouTube and Validation of the IVORY-Grading-System Quality of Septoplasty Videos Open
Objective This study aimed to analyze the educational quality of septoplasty videos on YouTube and validate the “Instructional Videos in Otorhinolaryngology by YO-IFOS-Grading-System” (IVORY-GS), the first otorhinolaryngology-specific vide…
View article: Measles Outbreak Associated with a Migrant Shelter — Chicago, Illinois, February–May 2024
Measles Outbreak Associated with a Migrant Shelter — Chicago, Illinois, February–May 2024 Open
Measles, a highly contagious respiratory virus with the potential to cause severe complications, hospitalization, and death, was declared eliminated from the United States in 2000; however, with ongoing global transmission, infections in t…
View article: Co-expression patterns of cancer associated fibroblast markers reveal distinct subgroups related to patient survival in oropharyngeal squamous cell carcinoma
Co-expression patterns of cancer associated fibroblast markers reveal distinct subgroups related to patient survival in oropharyngeal squamous cell carcinoma Open
Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) is rapidly increasing in high income countries due to its association with persistent high-risk human papilloma virus (HPV) infection. Recent scientific advances ha…
View article: 3D-exoscopic microlaryngoscopy in phonosurgery for glottic insufficiency
3D-exoscopic microlaryngoscopy in phonosurgery for glottic insufficiency Open
Purpose We hypothesized that using a 3D-exoscope (3Dex) in microlaryngoscopic phonosurgery is non-inferior to using a standard operating microscope (OM). To compare the above, we utilized a 3Dex and an OM for microlaryngoscopic vocal fold …
View article: Analysis of the Quality of Parotidectomy Videos on <scp>YouTube</scp> Using the <scp>IVORY‐Grading‐System</scp>
Analysis of the Quality of Parotidectomy Videos on <span>YouTube</span> Using the <span>IVORY‐Grading‐System</span> Open
Objective The aim of this study was to evaluate the quality and the educational content of YouTube videos showing parotidectomy. Methods We searched for videos displaying parotidectomy on YouTube. To rate parotidectomy videos, we introduce…
View article: Stimmlippenaugmentation mit autologem Fett unter Verwendung eines 3D-Exoskops
Stimmlippenaugmentation mit autologem Fett unter Verwendung eines 3D-Exoskops Open
Einführung: Stimmlippenaugmentation mit Eigenfett ist eine effektive Therapie bei einseitiger Stimmlippenparese. Im Laufe der Zeit wurde das operative Vorgehen unter anderem durch Liposuction und Zentrifugation schrittweise verbessert. Sei…
View article: New approaches in endoscopically assisted laryngeal surgery – A multimedia contribution.
New approaches in endoscopically assisted laryngeal surgery – A multimedia contribution. Open
Introduction Laryngeal exposure in direct laryngoscopy when using a Kleinsasser laryngoscope and the operating microscope may prove to be complicated at times. The use of angled endoscopes is a way to gain insight into laryngeal areas that…
View article: Vocal fold augmentation with autologous fat using a 3D-Exoscope
Vocal fold augmentation with autologous fat using a 3D-Exoscope Open
Introduction Vocal fold augmentation using autologous fat was demonstrated to be an effective solution for unilateral vocal fold paralysis. Developments such as liposuction and centrifugation have contributed to improving results. Since 20…
View article: Neue Ansätze bei endoskopisch assistierter Larynxchirurgie – Ein Multimediabeitrag
Neue Ansätze bei endoskopisch assistierter Larynxchirurgie – Ein Multimediabeitrag Open
Einleitung Der schwer einzustellende Larynx, bei welchem die direkte Einsicht der Glottisebene mit dem Operationsmikroskop unter Verwendung der Kleinsasser-Rohre erschwert ist, ist jedem operativ tätigen HNO-Arzt bekannt. Die Verwendung vo…
View article: European white paper: oropharyngeal dysphagia in head and neck cancer
European white paper: oropharyngeal dysphagia in head and neck cancer Open
View article: Vocal fold augmentation with autologous fat for glottic insufficiency
Vocal fold augmentation with autologous fat for glottic insufficiency Open
Introduction In this multimedia article we would like to demonstrate vocal fold augmentation with autologous fat as a therapy for glottal insufficiency. The patient population includes patients with symptomatic glottal insufficiency due to…
View article: Non-selective unilateral laryngeal reinnervation as salvage treatment after unsuccessful thyroplasty
Non-selective unilateral laryngeal reinnervation as salvage treatment after unsuccessful thyroplasty Open
Non-selective unilateral laryngeal reinnervation (ULR) is the surgical anastomosis between the recurrent laryngeal nerve (RLN) with a motor nerve in unilateral vocal fold paralysis (UVP). We present the results of nine patients in whom non…
View article: Nicht-selektive unilaterale laryngeale Reinnervation als Salvage-Therapie nach erfolgloser Thyreoplastik
Nicht-selektive unilaterale laryngeale Reinnervation als Salvage-Therapie nach erfolgloser Thyreoplastik Open
Nicht-selektive unilaterale laryngeale Reinnervation (ULR) ist die chirurgische Anastomose des N. laryngeus recurrens (NLR) mit einem motorischen Nerven bei einseitiger Stimmlippenparese. Präsentiert werden die Ergebnisse von neun Patiente…
View article: Destruction complex dynamics: Wnt/β-catenin signaling alters Axin-GSK3β interactions in<i>in vivo</i>
Destruction complex dynamics: Wnt/β-catenin signaling alters Axin-GSK3β interactions in<i>in vivo</i> Open
The central regulator of the Wnt/β-catenin pathway is the Axin/APC/GSK3β destruction complex (DC), which in unstimulated conditions targets cytoplasmic β-catenin for degradation. How Wnt activation inhibits the DC to permit β-catenin-depen…
View article: Nicht-selektive unilaterale laryngeale Reinnervation bei einseitiger Stimmlippenparalyse: Eine Evaluation der phoniatrischen Langzeit-Ergebnisse von 47 Patienten
Nicht-selektive unilaterale laryngeale Reinnervation bei einseitiger Stimmlippenparalyse: Eine Evaluation der phoniatrischen Langzeit-Ergebnisse von 47 Patienten Open
Nicht-selektive unilaterale laryngeale Reinnervation (ULR) ist die chirurgische Anastomose des N. laryngeus recurrens (NLR) mit einem motorischen, zervikalen Nerven bei einseitiger Stimmlippenparalyse. Präsentiert werden Ergebnisse von 47 …
View article: Non-selective unilateral laryngeal reinnervation in unilateral vocal cord paralysis: An evaluation of phoniatric long-term results of 47 patients
Non-selective unilateral laryngeal reinnervation in unilateral vocal cord paralysis: An evaluation of phoniatric long-term results of 47 patients Open
Non-selective unilateral laryngeal reinnervation (ULR) is the surgical anastomosis of the recurrent laryngeal nerve (RLN) with a further cervical nerve. We present results concerning the voice quality of 47 patients on whom non-selective U…
View article: Molecular Characterization of Human Atypical Sorbitol-Fermenting Enteropathogenic Escherichia coli O157 Reveals High Diversity
Molecular Characterization of Human Atypical Sorbitol-Fermenting Enteropathogenic Escherichia coli O157 Reveals High Diversity Open
Alongside the well-characterized enterohemorrhagic Escherichia coli (EHEC) O157:H7, serogroup O157 comprises sorbitol-fermenting typical and atypical enteropathogenic E. coli (EPEC/aEPEC) strains that carry the intimin-encoding gene eae bu…