Kevin Gallagher
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View article: Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy (WASHOUT) – study protocol
Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy (WASHOUT) – study protocol Open
Introduction Haematuria contributes significantly to emergency urology admissions with over 4 per 1000 annual UK emergency admissions and 10% readmitted within 30 days. However, there is limited focus on optimising inpatient pathways inter…
View article: The impact of haemostatic agent used during robot‐assisted radical prostatectomy on post‐op infection and anastomotic leak
The impact of haemostatic agent used during robot‐assisted radical prostatectomy on post‐op infection and anastomotic leak Open
Objective Despite the widespread use of robotic‐assisted radical prostatectomy (RARP), considerable variation exists in practice with regard to postoperative cystograms prior to trial without catheter (TWOC). Our practice was to undertake …
View article: The significance of isolated de novo red patches in the bladder in patients referred with suspected urinary tract cancer: Results from the IDENTIFY study
The significance of isolated de novo red patches in the bladder in patients referred with suspected urinary tract cancer: Results from the IDENTIFY study Open
Objectives To assess the contemporary malignancy rate in isolated de novo red patches in the bladder and associated risk factors for better selection of red patch biopsy. Patients Patients from the IDENTIFY dataset; Patients referred to se…
View article: Recent advancements in the Ward AdmSsion of Haematuria: an Observational mUlticentre sTudy ( <scp>WASHOUT)</scp> —a large‐scale observational multicentre study of inpatient haematuria
Recent advancements in the Ward AdmSsion of Haematuria: an Observational mUlticentre sTudy ( <span>WASHOUT)</span> —a large‐scale observational multicentre study of inpatient haematuria Open
Funding: The BURST Urology would like to acknowledge funding received from The Urology Foundation, Action Bladder Cancer UK and Charles Reynolds Foundation in support of this study.
View article: Early oncological outcomes of delayed radical prostatectomy: A prospective, international, follow‐up analysis of the COVIDSurg‐Cancer study
Early oncological outcomes of delayed radical prostatectomy: A prospective, international, follow‐up analysis of the COVIDSurg‐Cancer study Open
Objectives The objective of this study is to compare the early oncological outcomes of delayed (>90 days) versus scheduled (≤90 days) radical prostatectomy (RP). Patients and methods Patients with prostate cancer due to undergo surgery bet…
View article: Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Cancer study
Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Cancer study Open
Objective The objective of this study was to report the 12‐month oncological outcomes for patients with non‐muscle‐invasive bladder cancer (NMIBC) within the prospective, international COVIDSurg Cancer study. Patients and methods Eligible …
View article: 617 External Validation of the IDENTIFY Risk Calculator for Predicting Urinary Tract Cancer in Patients with Haematuria
617 External Validation of the IDENTIFY Risk Calculator for Predicting Urinary Tract Cancer in Patients with Haematuria Open
Aim Risk-stratification for patients referred with haematuria is important in diagnosing cancer early and for health resource efficiency. A recent prediction model developed from the IDENTIFY study created a cancer risk calculator that aim…
View article: Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis Open
Progressive fibrosis is a feature of aging and chronic tissue injury in multiple organs, including the kidney and heart. Glioma-associated oncogene 1 expressing (Gli1 + ) cells are a major source of activated fibroblasts in multiple organs…
View article: Audit, Feedback, and Education to Improve Quality and Outcomes in Transurethral Resection and Single-Instillation Intravesical Chemotherapy for Nonmuscle Invasive Bladder Cancer Treatment: Protocol for a Multicenter International Observational Study With an Embedded Cluster Randomized Trial
Audit, Feedback, and Education to Improve Quality and Outcomes in Transurethral Resection and Single-Instillation Intravesical Chemotherapy for Nonmuscle Invasive Bladder Cancer Treatment: Protocol for a Multicenter International Observational Study With an Embedded Cluster Randomized Trial Open
Background Nonmuscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancers. It is common and costly. Cost and detriment to patient outcomes and quality of life are driven by high recurrence rates and the need for regular inva…
View article: Study protocol: transurethral REsection and Single instillation intravesical chemotherapy Evaluation in bladder Cancer Treatment (RESECT). A multi-centre international observational study with embedded cluster randomised trial of audit, feedback and education. (Preprint)
Study protocol: transurethral REsection and Single instillation intravesical chemotherapy Evaluation in bladder Cancer Treatment (RESECT). A multi-centre international observational study with embedded cluster randomised trial of audit, feedback and education. (Preprint) Open
BACKGROUND Non-muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancers. It is common and costly. Cost and detriment to patient outcomes and quality of life are driven by high recurrence rates and the need for regular in…
View article: Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis
Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis Open
Progressive fibrosis and maladaptive organ repair result in significant morbidity and millions of premature deaths annually. Senescent cells accumulate with aging and after injury and are implicated in organ fibrosis, but the mechanisms by…
View article: Single cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis
Single cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis Open
Progressive fibrosis and maladaptive organ repair result in significant morbidity and millions of premature deaths annually. Senescent cells accumulate with ageing and after injury and are implicated in organ fibrosis, but the mechanisms b…
View article: NCOG-04. THE IMPACT OF PROPHYLAXIS CHEMOTHERAPY ON CENTRAL NERVOUS SYSTEM (CNS) RELAPSES OF HIGH RISK DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL): A NETWORK META-ANALYSIS
NCOG-04. THE IMPACT OF PROPHYLAXIS CHEMOTHERAPY ON CENTRAL NERVOUS SYSTEM (CNS) RELAPSES OF HIGH RISK DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL): A NETWORK META-ANALYSIS Open
BACKGROUND CNS relapses with DLBCL tend to be uncommon. The risk increases with certain DLBCL types and certain identified risk features. There is no consensus regarding the optimal approach to CNS prophylaxis for high-risk DLBCL patients.…
View article: 218 The Impact on Minimally Invasive Urological Cancer Surgery During the Covid-19 Pandemic
218 The Impact on Minimally Invasive Urological Cancer Surgery During the Covid-19 Pandemic Open
Aim Learned bodies recommended restricted use of, or extensive precautions when using, laparoscopic/robotic surgery during the Covid-19 pandemic. We aimed to determine whether minimally invasive surgery (MIS) in uro-oncology patients was s…
View article: The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study
The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study Open
Objective To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper tract urothelial cancer [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk…
View article: Aging Modulates the Effects of Ischemic Injury Upon Mesenchymal Cells within the Renal Interstitium and Microvasculature
Aging Modulates the Effects of Ischemic Injury Upon Mesenchymal Cells within the Renal Interstitium and Microvasculature Open
The renal mesenchyme contains heterogeneous cells, including interstitial fibroblasts and pericytes, with key roles in wound healing. Although healing is impaired in aged kidneys, the effect of age and injury on the mesenchyme remains poor…
View article: 92 Reshaping the Diagnostic Pathways for Investigation of Haematuria During and After The COVID-19 Pandemic: Diagnostic Accuracy of Strategies for Detection of Bladder Cancer from The IDENTIFY Cohort Study
92 Reshaping the Diagnostic Pathways for Investigation of Haematuria During and After The COVID-19 Pandemic: Diagnostic Accuracy of Strategies for Detection of Bladder Cancer from The IDENTIFY Cohort Study Open
Introduction Diagnostic haematuria services have been reduced due to the COVID-19 pandemic, compromising patient care, and necessitating a more pragmatic pathway. Method The IDENTIFY study was an international, prospective, multicentre coh…