Kevin Manley
YOU?
Author Swipe
View article: Altered meningeal immunity contributing to the autism-like behavior of BTBR T Itpr3/J mice
Altered meningeal immunity contributing to the autism-like behavior of BTBR T Itpr3/J mice Open
Autism spectrum disorder (ASD) is a complicated neurodevelopmental disorder, which is categorized by deficiency of social contact and communication, and stereotyped forms of performance. Meningeal immunity conditions the immune reflection …
View article: Altered meningeal immunity contributing to the autism-like behavior of BTBR<i>T</i><sup>+</sup><i>Itpr3<sup>tf</sup></i>/J mice
Altered meningeal immunity contributing to the autism-like behavior of BTBR<i>T</i><sup>+</sup><i>Itpr3<sup>tf</sup></i>/J mice Open
Autism spectrum disorder (ASD) is a complicated neurodevelopmental disorder, which is categorized by deficiency of social contact and communication, and stereotyped forms of performance. Meningeal immunity conditions the immune reflection …
View article: Combined autofluorescence and diffuse reflectance for brain tumour surgical guidance: initial ex vivo study results
Combined autofluorescence and diffuse reflectance for brain tumour surgical guidance: initial ex vivo study results Open
This ex vivo study was conducted to assess the potential of using a fibre optic probe system based on autofluorescence and diffuse reflectance for tissue differentiation in the brain. A total of 180 optical measurements were acquired from …
View article: Limits and Opportunities for Miniaturizing Ultrasonic Surgical Devices Based on a Langevin Transducer
Limits and Opportunities for Miniaturizing Ultrasonic Surgical Devices Based on a Langevin Transducer Open
Minimally invasive surgery offers opportunities for reduced morbidities, faster postoperative recovery, and reduced costs, and is a major focus of surgical device innovation. For ultrasonic surgical devices, which offer benefits of high pr…
View article: Cranial Perforation Using an Optically-Enhanced Surgical Drill
Cranial Perforation Using an Optically-Enhanced Surgical Drill Open
The design of mechanically clutched cranial perforators, used in craniotomy procedures, limits their performance under certain clinical conditions and can, in some cases, impose the risk of severe brain injury on patients undergoing the pr…
View article: Immunity and autoantibodies of a mouse strain with autistic-like behavior
Immunity and autoantibodies of a mouse strain with autistic-like behavior Open
Female and male mice of the BTBR T + Itpr3 tf /J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG …
View article: Diffuse reflectance spectroscopy-enhanced drill for bone boundary detection
Diffuse reflectance spectroscopy-enhanced drill for bone boundary detection Open
Intramedullary nailing is a routine orthopedic procedure used for treating fractures of femoral or tibial shafts. A critical part of this procedure involves the drilling of pilot holes in both ends of the bone for the placement of the scre…
View article: Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington′s disease
Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington′s disease Open
Immunotherapy, both active and passive, is increasingly recognized as a powerful approach to a wide range of diseases, including Alzheimer's and Parkinson's. Huntington's disease (HD), an autosomal dominant disorder triggered by misfolding…