Kevin M. Elias YOU? Author Swipe

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Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines Open

Kornél Lakatos, Kevin M. Elias, Kathleen T Hasselblatt, György Végh, Thomas F. McElrath , et al. · 2025

There are certain similarities between the immune evasion of tumor cells and the physiological invasion of the trophoblastic cells of embryonic origin into the maternal decidua. Understanding the ways of interaction between dNK cells and t…

Initial Treatment and Outcomes of Complete Hydatidiform Mole in Women 40 Years or Older: A Multicenter Cohort Study Open

Cecília Canêdo Freitas Desmarais, Izildinha Maestá, Sue Yazaki Sun, Jorge Rezende-Filho, Roberto Costa , et al. · 2025

Objectives: To evaluate the potential associations of the type of complete hydatidiform mole (CHM) initial treatment (hysterectomy or uterine evacuation) with GTN development, need for chemotherapy, and treatment outcome in women aged ≥ 40…

Clinical Evaluation of a Multi-Omic Diagnostic Model for Early-Stage Ovarian Cancer Detection Open

Robert Adger Law, Brendan M. Giles, Rachel Culp‐Hill, Enkhtuya Radnaa, Melvyn Goldberg , et al. · 2025

Background/Objectives: Ovarian cancer (OC) is frequently diagnosed at an advanced stage due to the nonspecific nature of its symptoms. While population-wide screening has failed to reduce mortality, timely diagnosis in symptomatic women re…

Pattern of Semen Parameters of Sub-fertile Males Attending an Infertility Clinic at a Tertiary Level Hospital in Bangladesh Open

Joya Biswas, Kshitish Chandra Talukder, Mohammad Mizanur Rahman, Md. Liakat Hossain, Tania Akter , et al. · 2025

Sub-fertility is an upsetting situation for childless couples who are experiencing a lot of physical, mental, social, and economic trauma. Many women go to an infertility clinic or gynecologist without their husbands because it is still co…

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer Open

Paweł Kordowitzki, Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner , et al. · 2025

High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with t…

Figure S3 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Significant miRNA changes for age, menopause and bilateral salpingo-oophorectomy (BSO)

Data from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Background:Serum miRNAs are potential biomarkers for ovarian cancer; however, many factors may influence miRNA expression. To understand potential confounders in miRNA analysis, we examined how sociodemographic factors and comorbidities, i…

Table S2 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

List of miRNA panel

Raw data from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Raw data, miRNAs and clinical data

Table S3 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Patient characteristics in tSNE clusters

Figure S2 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Univariate analysis of clinical variables with miRNAs.

Figure S4 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Gene set enrichment analysis

Table S1 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Patient characteristics

Figure S1 from Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2025

Log2 expression values of miRNAs used for statistical tests.

Tribus: semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomic data Open

Ziqi Kang, Angela E. Szabó, Teodora Farago, Fernando Pérez‐Villatoro, Ada Junquera , et al. · 2025

Motivation Multiplexed imaging and single-cell analysis are increasingly applied to investigate the tissue spatial ecosystems in cancer and other complex diseases. Accurate single-cell phenotyping based on marker combinations is a critical…

Pembrolizumab in gestational trophoblastic neoplasia: Systematic review and meta-analysis with sub-group analysis of potential prognostic factors Open

Márcio Barcellos, Antônio Braga, Matheus Machado Rech, Solange Artimos de Oliveira, José Mauro Madi , et al. · 2025

Response to commentary on “pembrolizumab in gestational trophoblastic neoplasia: systematic review and meta-analysis with sub-group analysis of potential prognostic factors” Open

Márcio Barcellos, Antônio Braga, Matheus Machado Rech, Solange Artimos de Oliveira, José Mauro Madi , et al. · 2025

Serum miRNA improves the accuracy of a multivariate index assay for triage of an adnexal mass Open

James W. Webber, Laura Wollborn, Sudhanshu Mishra, Allison F. Vitonis, Daniel W. Cramer , et al. · 2024

A multimodal assay combining miRNA with protein biomarkers, age, and menopausal status improves surgical triage of an adnexal mass.

Validation of miRNA signatures for ovarian cancer earlier detection in the pre-diagnosis setting using machine learning approaches Open

Konrad Stawiski, Renée T. Fortner, Luca Pestarino, Sinan U. Umu, Rudolf Kaaks , et al. · 2024

Introduction Effective strategies for early detection of epithelial ovarian cancer are lacking. We evaluated whether a panel of 14 previously established circulating microRNAs could discriminate between cases diagnosed <2 years after se…

Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer Open

Laura Wollborn, James W. Webber, Stephanie Alimena, Sudhanshu Mishra, Chad B. Sussman , et al. · 2024

Background: Serum miRNAs are potential biomarkers for ovarian cancer; however, many factors may influence miRNA expression. To understand potential confounders in miRNA analysis, we examined how sociodemographic factors and comorbidities, …

Plasma microRNA expression in adolescents and young adults with endometriosis: the importance of hormone use Open

Paula C. Brady, Abdelrahman Yousif, Naoko Sasamoto, Allison F. Vitonis, Wojciech Fendler , et al. · 2024

Introduction Prior studies have investigated the diagnostic potential of microRNA (miRNA) expression profiles for endometriosis. However, the vast majority of previous studies have only included adult women. Therefore, we sought to investi…

Supplemental Figure 1 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Figure 1: Differences by individual racial subtypes for each of the eight miRNA related to ovarian cancer risk. Values for individual miRNAs were compared across different racial subtypes using pairwise t-tests. The images in …

Sialyl-Tn serves as a potential therapeutic target for ovarian cancer Open

Linah Al-Alem, Jillian M. Prendergast, Justin Clark, Bianca Zarrella, Dominique T. Zarrella , et al. · 2024

Background Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been limited advances in treatment strategies that have seen marked increases in overall survival. Thus, it is essential to continu…

Data from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Serum miRNAs are promising biomarkers for several clinical conditions, including ovarian cancer. To inform equitable implementation of these tests, we investigated the effects of race, ethnicity, and socioeconomic status on serum miRNA pro…

Supplemental Table 3 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Table 3 shows the ratio of non-white mean fluorescence units (MFI) to white MFI for the eight miRNA associated with ovarian cancer risk. MFI for non-white patients were on average higher for these race-associated miRNA compare…

Data from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Serum miRNAs are promising biomarkers for several clinical conditions, including ovarian cancer. To inform equitable implementation of these tests, we investigated the effects of race, ethnicity, and socioeconomic status on serum miRNA pro…

Supplemental Table 1 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Table 1: Differences in 179 individual miRNA studied by white vs non-white race/ethnicity. Here we show p-values for both univariate analysis and multiple linear regression analysis controlling for confounding factors. The ass…

Supplemental Table 2 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Table 2: Correlation between all tested socioeconomic indices and miRNA values for eight miRNA previously associated with ovarian cancer risk, among Massachusetts residents. We confined this analysis to Massachusetts residents…

Supplemental Figure 1 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Figure 1: Differences by individual racial subtypes for each of the eight miRNA related to ovarian cancer risk. Values for individual miRNAs were compared across different racial subtypes using pairwise t-tests. The images in …

Supplemental Table 2 from Differences in Serum miRNA Profiles by Race, Ethnicity, and Socioeconomic Status: Implications for Developing an Equitable Ovarian Cancer Screening Test Open

Stephanie Alimena, Briana Stephenson, James W. Webber, Laura Wollborn, Chad B. Sussman , et al. · 2024

Supplemental Table 2: Correlation between all tested socioeconomic indices and miRNA values for eight miRNA previously associated with ovarian cancer risk, among Massachusetts residents. We confined this analysis to Massachusetts residents…

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