Kun Yang
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View article: Mobile versus traditional neuropsychological testing in Ecuadorian adolescents and young adults: A single- and burst-administration study in the Study of Secondary Exposures to Pesticides Among Children, Adolescents, and Adults (ESPINA) cohort.
Mobile versus traditional neuropsychological testing in Ecuadorian adolescents and young adults: A single- and burst-administration study in the Study of Secondary Exposures to Pesticides Among Children, Adolescents, and Adults (ESPINA) cohort. Open
Mobile cognitive testing shows considerable promise for assessing cognition among Spanish-speaking Latin American adolescents and young adults, revealing significant associations with tablet-based cognitive assessments, and may be generali…
View article: A novel biliary-specific near-infrared fluorescent dye (BL-760) enhances visualization of the biliary tree in a swine inflammatory model of bile duct obstruction
A novel biliary-specific near-infrared fluorescent dye (BL-760) enhances visualization of the biliary tree in a swine inflammatory model of bile duct obstruction Open
Background Bile duct injury (BDI) is a morbid complication of laparoscopic cholecystectomy due to poor recognition of the anatomy and inadequate visualization of the extra-hepatic biliary ducts. Near-infrared indocyanine green (ICG) is the…
View article: Comparison of expandable and titanium cages in anterior cervical corpectomy for OPLL with osteoporosis: A retrospective matched study
Comparison of expandable and titanium cages in anterior cervical corpectomy for OPLL with osteoporosis: A retrospective matched study Open
Anterior cervical corpectomy and fusion (ACCF) is commonly used to treat cervical ossification of the posterior longitudinal ligament (OPLL). In patients with concurrent osteoporosis, titanium cage fusion (TCF) may lead to increased implan…
View article: Dosage and safety of transcranial magnetic stimulation and transcranial direct current stimulation for managing patients with chronic musculoskeletal pain: a scoping review protocol
Dosage and safety of transcranial magnetic stimulation and transcranial direct current stimulation for managing patients with chronic musculoskeletal pain: a scoping review protocol Open
Introduction Although emerging evidence supports the short-term efficacy of transcranial magnetic stimulation (TMS), including repetitive TMS (rTMS) and theta-burst transcranial magnetic stimulation (TBS-TMS), and transcranial direct curre…
View article: Pesticide and Liver Biomarkers Among Ecuadorian Adolescents and Adults Living in Agricultural Settings
Pesticide and Liver Biomarkers Among Ecuadorian Adolescents and Adults Living in Agricultural Settings Open
Background: Experimental studies suggest that some insecticides, fungicides, and herbicides can result in liver cell death, but population-based evidence is lacking. We investigated associations between urinary pesticide metabolites and li…
View article: The relationship between hearing loss and cognitive function in the elderly: the mediating effect of social isolation
The relationship between hearing loss and cognitive function in the elderly: the mediating effect of social isolation Open
View article: Characterization of immune features and discovery of potential biomarkers for ankylosing spondylitis using deep plasma proteomics
Characterization of immune features and discovery of potential biomarkers for ankylosing spondylitis using deep plasma proteomics Open
By integrating the machine learning-based method with deep proteomics analysis, we explored the pathological mechanism and identified biomarkers for AS. Our study provides insights into the distinct protein expression patterns and pathogen…
View article: Study on the safety and efficacy of Fu's subcutaneous needling for the treatment of lumbar disc herniation: a systematic review and meta analysis of randomized controlled trials
Study on the safety and efficacy of Fu's subcutaneous needling for the treatment of lumbar disc herniation: a systematic review and meta analysis of randomized controlled trials Open
Purpose Systematic evaluation of the effectiveness and safety of Fu's Subcutaneous Needling (FSN) in the treatment of Lumbar Disc Herniation. Methods A systematic search was conducted across four Chinese and four English databases, includi…
View article: Distal small bowel resection with the preservation of terminal ileum suppresses hepatic gluconeogenesis via the Prevotellaceae_NK3B31_group-mediated 7-KLCA-FXR axis
Distal small bowel resection with the preservation of terminal ileum suppresses hepatic gluconeogenesis via the Prevotellaceae_NK3B31_group-mediated 7-KLCA-FXR axis Open
Previous studies have indicated that distal small bowel resection with preservation of the terminal ileum (DBRPI) significantly lowers blood glucose levels and improves glucose tolerance, presumably through mechanisms involving increased b…
View article: The status and correlation factors of fatigue in patients with ankylosing spondylitis (FACIT-F): a cross-sectional study based on the Chinese population
The status and correlation factors of fatigue in patients with ankylosing spondylitis (FACIT-F): a cross-sectional study based on the Chinese population Open
In this study, fatigue was obvious in 37.9% of AS patients, and patients' fatigue levels were closely related to disease activity (ASDAS, BASDAI and PGA) and psychological factors (anxiety, depression and stress). At the same time, the hig…
View article: Homogenized daily sunshine duration over China from 1961 to 2022
Homogenized daily sunshine duration over China from 1961 to 2022 Open
Inhomogeneities in the sunshine duration (SSD) observational series, caused by non-climatic factors like China’s widespread transition from manual to automatic SSD recorders in 2019 or station relocations, have hindered accurate esti…
View article: Correlates of depression, anxiety, and stress among patients with ankylosing spondylitis
Correlates of depression, anxiety, and stress among patients with ankylosing spondylitis Open
The study reveals a significant prevalence of psychological disorders among individuals with AS, which correlates closely with disease activity, health index, fatigue levels, and PGA. These findings highlight the imperative for assessment …
View article: Prediction model for psychological disorders in ankylosing spondylitis patients based on multi-label classification
Prediction model for psychological disorders in ankylosing spondylitis patients based on multi-label classification Open
Objective This study aims to develop a predictive model to assess the likelihood of psychological disorders in patients with ankylosing spondylitis (AS) and to explore the relationships between different factors and psychological disorders…
View article: Saturn’s G ring: insights from the dynamical evolution of dust particles from the G-ring arc
Saturn’s G ring: insights from the dynamical evolution of dust particles from the G-ring arc Open
To explore the formation and properties of Saturn’s G ring, we study the dynamics of micrometre-sized dust particles originating from the arc of debris near the inner edge of the ring. The dynamical evolution of particles due to various pe…
View article: Prevalence, influencing factors, and prediction model construction of anemia in ankylosing spondylitis based on real-world data: An exploratory study
Prevalence, influencing factors, and prediction model construction of anemia in ankylosing spondylitis based on real-world data: An exploratory study Open
Objective This study aimed to explore the prevalence and influencing factors of anemia in patients with ankylosing spondylitis (AS) using real-world data and to construct a predictive model for anemia in AS. Methods In November 2023, we ac…
View article: Multimodal assessment predicts cognitive impairment after aneurysmal subarachnoid hemorrhage: a prospective cohort study
Multimodal assessment predicts cognitive impairment after aneurysmal subarachnoid hemorrhage: a prospective cohort study Open
Background: Risk factors and mechanisms of cognitive impairment (CI) after aneurysmal subarachnoid hemorrhage (aSAH) are unclear. This study used a neuropsychological battery, MRI, ERP and CSF and plasma biomarkers to predict long-term cog…
View article: Proximal small intestinal bypass outperforms Roux-en-Y and jejunoileal bypass in glucose regulation in streptozotocin induced diabetic rats
Proximal small intestinal bypass outperforms Roux-en-Y and jejunoileal bypass in glucose regulation in streptozotocin induced diabetic rats Open
BACKGROUND The efficacy of various bariatric surgeries varies in reducing blood glucose levels. Given the distinct mechanisms and anatomical alterations associated with each procedure, it is crucial to compare their glycemic control outcom…
View article: Temporal Trends of Modifiable Risk Factors for Dementia in the United States from 2006 to 2020
Temporal Trends of Modifiable Risk Factors for Dementia in the United States from 2006 to 2020 Open
View article: Sustained TCE Dechlorination to Ethene Under High Pfos Stress: Role of Resilient Dehalococcoides
Sustained TCE Dechlorination to Ethene Under High Pfos Stress: Role of Resilient Dehalococcoides Open
View article: Alterations of oscillatory activity and cognitive function after aneurysmal subarachnoid hemorrhage
Alterations of oscillatory activity and cognitive function after aneurysmal subarachnoid hemorrhage Open
Background: Aneurysmal subarachnoid hemorrhage (aSAH) can lead to cognitive impairment (CI), but underlying neural mechanisms remain to be elucidated. Materials and methods: To predict long-term CI after aSAH, resting electroencephalograph…
View article: Homogenized daily sunshine duration over China from 1961 to 2022
Homogenized daily sunshine duration over China from 1961 to 2022 Open
Inhomogeneities in the sunshine duration (SSD) observational series, caused by non-climatic factors like China’s widespread transition from manual to automatic SSD recorders in 2019 or station relocations, have hindered accurate estimate o…
View article: Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021
Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021 Open
INTRODUCTION We examined the burden of Alzheimer's disease and other dementias (ADOD) and attributable factors at the national and provincial levels in China. METHODS Using the Global Burden of Diseases Study 2021, we estimated incidence, …
View article: Proximal Small Intestine Bypass Outperforms Roux-en-Y and Jejunoileal Bypass in Glucose Regulation in Streptozotocin‑Induced Diabetic Rats
Proximal Small Intestine Bypass Outperforms Roux-en-Y and Jejunoileal Bypass in Glucose Regulation in Streptozotocin‑Induced Diabetic Rats Open
Background This study aimed to compare the efficacy of modified proximal small intestine bypass (PSIB), Roux-en-Y gastric bypass (RYGB), and conventional jejunoileal bypass (JIB) in weight loss and glucose metabolism in streptozotocin (STZ…
View article: A comprehensive index to evaluate cognitive health at the population scale
A comprehensive index to evaluate cognitive health at the population scale Open
Cognitive health is a major determinant of human survival and quality of life. As an increasing proportion of the global population reaches old age (defined as 60 years and older), dementia has become a public health and social care priori…
View article: Associations between Pesticide Metabolites and Inflammatory Biomarkers in Adolescents and Children Living in an Agricultural Region
Associations between Pesticide Metabolites and Inflammatory Biomarkers in Adolescents and Children Living in an Agricultural Region Open
View article: Associations of serum per- and polyfluoroalkyl substances with liver biomarkers and urinary creatinine in Ecuadorian adolescents: the ESPINA study
Associations of serum per- and polyfluoroalkyl substances with liver biomarkers and urinary creatinine in Ecuadorian adolescents: the ESPINA study Open
View article: Correlates of depression, anxiety, and stress among patients with ankylosing spondylitis
Correlates of depression, anxiety, and stress among patients with ankylosing spondylitis Open
Background The recurrent nature and prolonged course of ankylosing spondylitis (AS) impose substantial psychological disorders on patients. The aim of this study was to assess psychological disorders and analyze the overall risk of psychol…
View article: Assessment of Left Ventricular Diastolic Function in Patients with Diffuse LargeB-cell Lymphoma after Anthracycline Chemotherapy by using Vector FlowMapping
Assessment of Left Ventricular Diastolic Function in Patients with Diffuse LargeB-cell Lymphoma after Anthracycline Chemotherapy by using Vector FlowMapping Open
Background: Patients with diffuse large B-cell lymphoma (DLBCL) often experience a poor prognosis due to cardiac damage induced by anthracycline chemotherapy, with left ventricular diastolic dysfunction manifesting early. Vector Flow Mappi…
View article: Stroke and its diagnosis age on incidence dementia, and the mediating role of inflammation: A matched cohort study
Stroke and its diagnosis age on incidence dementia, and the mediating role of inflammation: A matched cohort study Open
Background We aimed to determine whether and to what extent the joint effect of stroke and age of stroke diagnosis on incident dementia, and to investigate whether inflammation indicators mediate the stroke-dementia relationship. Methods W…
View article: Clinical value of the Patient Global Assessment with Ankylosing Spondylitis: A cross-sectional study
Clinical value of the Patient Global Assessment with Ankylosing Spondylitis: A cross-sectional study Open
To analyze the factors associated with the overall patient condition and explore the clinical value of the Patient Global Assessment (PGA) index for assessing the disease state in patients with Ankylosing Spondylitis (AS). This cross-secti…