Keyang Zheng
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View article: Intra-Arterial Thrombolysis Following Endovascular Recanalization for Large Vessel Occlusion Stroke
Intra-Arterial Thrombolysis Following Endovascular Recanalization for Large Vessel Occlusion Stroke Open
Among patients with AIS due to LVO, IAT after endovascular recanalization adds additional benefits to functional outcomes, with no increased risk of death or intracranial hemorrhage.
View article: Clopidogrel vs. ticagrelor in ST-elevation myocardial infarction complicated by cardiogenic shock undergoing primary PCI
Clopidogrel vs. ticagrelor in ST-elevation myocardial infarction complicated by cardiogenic shock undergoing primary PCI Open
ClinicalTrials.gov, NCT02306616. Registered 29 November 2014.
View article: Comparative analysis of inflammatory markers as predictive markers for postoperative delirium in cardiac surgery patients: an observational study
Comparative analysis of inflammatory markers as predictive markers for postoperative delirium in cardiac surgery patients: an observational study Open
Background Postoperative delirium (POD) is a common complication following cardiac surgery that significantly affects patient outcomes. Among inflammatory markers, the monocyte-to-lymphocyte ratio (MLR) has shown potential in predicting PO…
View article: Association Between Visit‐to‐Visit Blood Pressure Variability and Incidence of Atrial Fibrillation in Hypertensive Patients: A Post‐Hoc Analysis of the SPRINT Trial
Association Between Visit‐to‐Visit Blood Pressure Variability and Incidence of Atrial Fibrillation in Hypertensive Patients: A Post‐Hoc Analysis of the SPRINT Trial Open
Visit‐to‐visit blood pressure variability (BPV) has been recognized as a cardiovascular risk factor, but its association with new‐onset atrial fibrillation (AF) remains underexplored. This study investigated the relationship between BPV an…
View article: Safety and efficacy of post-procedure anticoagulation in ST-elevation myocardial infarction complicated by cardiogenic shock undergoing primary percutaneous coronary intervention
Safety and efficacy of post-procedure anticoagulation in ST-elevation myocardial infarction complicated by cardiogenic shock undergoing primary percutaneous coronary intervention Open
View article: Sex difference in the relationship between childhood obesity and abnormal lipid profiles in young adults
Sex difference in the relationship between childhood obesity and abnormal lipid profiles in young adults Open
This study demonstrates a sex difference in the relationship between childhood obesity and abnormal lipid profiles in young adults. Childhood overweight/obesity is associated with adverse lipid profiles in adulthood, with different pattern…
View article: Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999–2020
Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999–2020 Open
View article: The effect of <scp>HbA1c</scp> variability on the efficacy of intensive blood pressure control in patients with type 2 diabetes
The effect of <span>HbA1c</span> variability on the efficacy of intensive blood pressure control in patients with type 2 diabetes Open
Aims The efficacy of intensive blood pressure (BP) control remains controversial, and the variability of HbA1c was a risk factor for macrovascular events in patients with type 2 diabetes. We investigated whether the HbA1c variability modif…
View article: J-shaped association between serum glucose potassium ratio and prognosis in heart failure with preserved ejection fraction with stronger predictive value in non-diabetic patients
J-shaped association between serum glucose potassium ratio and prognosis in heart failure with preserved ejection fraction with stronger predictive value in non-diabetic patients Open
A J-shaped relationship was existed between GPR levels and the primary outcome in HFpEF patients. An increased GPR was an independent predictor of poor prognosis in HFpEF patients, especially in non-diabetic patients and those with less se…
View article: Normalized lactate load as an independent prognostic indicator in patients with cardiogenic shock
Normalized lactate load as an independent prognostic indicator in patients with cardiogenic shock Open
View article: Triglyceride glucose index as a predictor for non-alcoholic fatty liver disease: insights from a longitudinal analysis in non-obese individuals
Triglyceride glucose index as a predictor for non-alcoholic fatty liver disease: insights from a longitudinal analysis in non-obese individuals Open
Background A substantial portion of non-obese population is afflicted with Non-alcoholic Fatty Liver Disease (NAFLD). The Triglyceride Glucose (TyG) index, a quantifier of insulin resistance magnitude, is determined by the product of fasti…
View article: Association Between the Hepatic Steatosis Index and Risk of Incident Type 2 Diabetes Mellitus in the Normoglycemic Population:A Longitudinal Prospective Study in Japan
Association Between the Hepatic Steatosis Index and Risk of Incident Type 2 Diabetes Mellitus in the Normoglycemic Population:A Longitudinal Prospective Study in Japan Open
This study highlights the significant association between elevated HSI levels and the likelihood of developing incident T2DM in individuals with normal glucose levels. Furthermore, it offers a simple and valuable screening tool for predict…
View article: The association between frailty and in-hospital mortality in critically ill patients with congestive heart failure: results from MIMIC-IV database
The association between frailty and in-hospital mortality in critically ill patients with congestive heart failure: results from MIMIC-IV database Open
Background Frailty correlates with adverse outcomes in many cardiovascular diseases and is prevalent in individuals with heart failure (HF). The Hospital Frailty Risk Score (HFRS) offers an integrated, validated solution for frailty assess…
View article: Corrigendum: Comparison of cerebrospinal fluid space between probable normal pressure hydrocephalus and Alzheimer's disease
Corrigendum: Comparison of cerebrospinal fluid space between probable normal pressure hydrocephalus and Alzheimer's disease Open
[This corrects the article DOI: 10.3389/fnagi.2023.1241237.].
View article: Association between the ZJU index and risk of new-onset non-alcoholic fatty liver disease in non-obese participants: a Chinese longitudinal prospective cohort study
Association between the ZJU index and risk of new-onset non-alcoholic fatty liver disease in non-obese participants: a Chinese longitudinal prospective cohort study Open
Background Non-alcoholic fatty liver disease (NAFLD) is increasingly observed in non-obese individuals. The ZJU (Zhejiang University) index has been established as a new and efficient tool for detecting NAFLD, but the relationship between …
View article: Elevated Glucose on Admission Was an Independent Risk Factor for 30-Day Major Adverse Cardiovascular Events in Patients with STEMI but Not NSTEMI
Elevated Glucose on Admission Was an Independent Risk Factor for 30-Day Major Adverse Cardiovascular Events in Patients with STEMI but Not NSTEMI Open
Background: The purpose of this study was to evaluate the impact of glucose levels on admission, on the risk of 30-day major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI), and to assess the differ…
View article: Comparison of cerebrospinal fluid space between probable normal pressure hydrocephalus and Alzheimer’s disease
Comparison of cerebrospinal fluid space between probable normal pressure hydrocephalus and Alzheimer’s disease Open
Introduction Idiopathic normal pressure hydrocephalus (INPH) is a potentially reversible syndrome characterized by complex symptoms, difficulty in diagnosis and a lack of detailed clinical description, and it is difficult to distinguish fr…
View article: Association between admission heart rate and major adverse cardiovascular events in acute myocardial infarction participants with different left ventricular ejection fraction
Association between admission heart rate and major adverse cardiovascular events in acute myocardial infarction participants with different left ventricular ejection fraction Open
This study found that elevated admission HR was associated with a significantly higher risk for MACEs in patients admitted with AMI. Elevated admission HR was significantly associated with the risk of MACEs in AMI patients without low LVEF…
View article: Weight cycling and risk of clinical adverse events in patients with heart failure with preserved ejection fraction: a post-hoc analysis of TOPCAT
Weight cycling and risk of clinical adverse events in patients with heart failure with preserved ejection fraction: a post-hoc analysis of TOPCAT Open
Background Previous studies hardly evaluated the association of variability of body mass index (BMI) or waist circumference with clinical adverse events and investigated whether weight cycling had an effect on the prognosis of patients wit…
View article: Elevated Glucose on Admission Was an Independent Risk Factor For 30-Day Major Adverse Cardiovascular Events in Patients with STEMI But Not NSTEMI
Elevated Glucose on Admission Was an Independent Risk Factor For 30-Day Major Adverse Cardiovascular Events in Patients with STEMI But Not NSTEMI Open
Objectives The purpose of this study was to evaluate the impact of glucose levels on admission on the risk of 30-day major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI), and to assess the differen…
View article: Association between the atherogenic index of plasma and major adverse cardiovascular events among non-diabetic hypertensive older adults
Association between the atherogenic index of plasma and major adverse cardiovascular events among non-diabetic hypertensive older adults Open
View article: Elevated admission blood glucose is an independent risk factor for 30-Day major adverse cardiovascular events in STEMI patients, but not in NSTEMI patients
Elevated admission blood glucose is an independent risk factor for 30-Day major adverse cardiovascular events in STEMI patients, but not in NSTEMI patients Open
Background Elevated admission blood glucose was associated with adverse outcomes in patients with acute myocardial infarction (AMI). However, no further studies investigated the association between admission blood glucose and 30-day major …
View article: Association between the atherogenic index of plasma and major adverse cardiovascular events among non-diabetic hypertensive elderly patients
Association between the atherogenic index of plasma and major adverse cardiovascular events among non-diabetic hypertensive elderly patients Open
Background: The literature on the association between the atherogenic index of plasma (AIP) with the risk of major adverse cardiovascular events (MACEs) among non-diabetic hypertensive elderly patients is quite limited at present. Methods:…
View article: The Impact of Cognitive Function on the Effectiveness and Safety of Intensive Blood Pressure Control for Patients With Hypertension: A post-hoc Analysis of SPRINT
The Impact of Cognitive Function on the Effectiveness and Safety of Intensive Blood Pressure Control for Patients With Hypertension: A post-hoc Analysis of SPRINT Open
Background: Poor cognitive function can predict poor clinical outcomes. Intensive blood pressure control can reduce the risk of cardiovascular diseases and all-cause mortality. In this study, we assessed whether intensive blood pressure co…
View article: Hb Levels and Sex Differences in Relation to Short-Term Outcomes in Patients With Acute Myocardial Infarction
Hb Levels and Sex Differences in Relation to Short-Term Outcomes in Patients With Acute Myocardial Infarction Open
Background: Women had worse outcomes after acute myocardial infarction (AMI), and physiologically, women had lower hemoglobin values. We examined whether there were sex-related differences in the relationship between hemoglobin levels and …
View article: Anemia in Patients with Takayasu’s Arteritis and its Correlation with Disease Activity
Anemia in Patients with Takayasu’s Arteritis and its Correlation with Disease Activity Open
Background Anemia is a common clinical condition in autoimmune disease, but there are few related studies in Takayasu’s arteritis (TAK). The purpose of this study is to detect clinical characteristics of anemia patients with TAK and to exp…
View article: Efficacy of ARB/HCTZ Combination Therapy in Uncontrolled Hypertensive Patients Compared with ARB Monotherapy: A Meta-Analysis
Efficacy of ARB/HCTZ Combination Therapy in Uncontrolled Hypertensive Patients Compared with ARB Monotherapy: A Meta-Analysis Open
Objective. To evaluate the efficacy of combination of angiotensin receptor blocker (ARB) with hydrochlorothiazide (HCTZ) compared to ARB alone in patients with uncontrolled hypertension via a systematic review and meta-analysis. Methods. W…
View article: High‐density lipoprotein cholesterol levels are associated with major adverse cardiovascular events in male but not female patients with hypertension
High‐density lipoprotein cholesterol levels are associated with major adverse cardiovascular events in male but not female patients with hypertension Open
Background The relationship between high‐density lipoprotein cholesterol (HDL‐C) levels and major adverse cardiovascular events (MACEs) in hypertensive patients of different sexes is unclear. Hypothesis Sex differences in the relationship …
View article: Short‐term and long‐term outcomes of revascularization interventions for patients with severely reduced left ventricular ejection fraction: a meta‐analysis
Short‐term and long‐term outcomes of revascularization interventions for patients with severely reduced left ventricular ejection fraction: a meta‐analysis Open
Aims This meta‐analysis aimed to determine whether coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) should be preferred in patients with severely reduced left ventricular (LV) ejection fraction. Methods an…