Truly isolated aneurysms of the superficial femoral artery (SFA) are uncommon. The treatment options come from small case series and case reports. In the absence of definitive management guidelines, a revision of the available literature was carried out. True SFA aneurysms are more common in elderly male patients and tend to present late and can grow to significant sizes. Both open and endovascular options are available, which will depend on many factors highlighted in this review. Open repair should be offered to…

Abstract Introduction Routine utilization of multigene assays to inform operative decision-making in early breast cancer (EBC) treatment is yet to be established. In this pilot study, we sought to establish the potential benefits of surgical intervention in EBC based on recurrence risk quantification using the Oncotype DX (ODX) assay. Materials and Methods Consecutive ODX tests performed over a 9-year period from October 2007 to May 2016 were evaluated. Oncotype scores were classified into high (≥31), medium (18–3…

A well-functioning Arteriovenous Fistula (AVF) has been shown to be the best modality for vascular access in patients with End-Stage Renal Disease (ESRD) that require haemodialysis (HD).A mature AVF has lower incidence of thrombosis and stenosis compared to the other two modalities; Arteriovenous Grafts (AVGs) and Central Venous Catheters (CVCs).That translates into prolonged patency rates and lower risk for infection.However, it has been reported that around 20% -50% of fistulae fail to mature into a useable acce…

Abstract. Background: Supervised exercise therapy (SET) is an effective option in the management of peripheral arterial disease (PAD). Unfortunately, poor compliance remains prevalent. This study aimed to assess patient exercise compliance and to identify factors influencing symptomatic improvement and SET participation. Patients and methods: Data regarding attendance at SET for this cohort study were extracted from a prospectively maintained database of patients with claudication attending SET at Dublin City Univ…

A well-functioning Arteriovenous Fistula (AVF) has been shown to be the best modality for access in patients with end-stage kidney disease going for dialysis. Maturation of AVF is complex and depends on various biomechanical forces induced into the vascular system following creation of AVF. The focus of this thesis was to study factors that can lead to optimising fistula maturation in patients with End Stage Renal Disease (ESRD). The author looked into various factors related to patients’ demographics and clinical…