Muhammad Khalid
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View article: “Microbial metabolites in cardioprotection: an immune-engineered framework for heart failure and post-ischemic remodeling - a narrative review”
“Microbial metabolites in cardioprotection: an immune-engineered framework for heart failure and post-ischemic remodeling - a narrative review” Open
Background: The gut-heart axis is a new therapeutic target for cardiovascular diseases (CVDs), which continue to be the leading cause of death worldwide. Metabolites originating from microorganisms have demonstrated significant impacts on …
View article: Integration of Multi‐Cereals Into Wheat Flour: Nutritional Composition, Dough Rheology, and Sensory Profile of Composite Breads
Integration of Multi‐Cereals Into Wheat Flour: Nutritional Composition, Dough Rheology, and Sensory Profile of Composite Breads Open
Bread, one of the most widely consumed staple foods, is traditionally prepared from whole wheat flour owing to its high gluten content and desirable physiochemical properties. However, growing consumer demand for nutrient‐dense functional …
View article: Hidden danger in our food packaging: The health risks of plastic monomers
Hidden danger in our food packaging: The health risks of plastic monomers Open
Plastic packaging is produced through a process called polymerization, where monomers (the building blocks) are linked together. Usually, monomers are stable in the polymer chain; however, the presence of low molecular weight substances, s…
View article: Protective effect of platelet-rich fibrin (PRF) against dry socket following surgical extraction of the mandibular third molar
Protective effect of platelet-rich fibrin (PRF) against dry socket following surgical extraction of the mandibular third molar Open
BACKGROUND & OBJECTIVE: Dry socket (DS) is one of the most painful complications following tooth extraction. Various preventive measures have been suggested over the years, but results remain inconclusive. This study aimed to evaluate the …
View article: An 18‐Year‐Old Congenitally Deaf and Mute Male With Prolonged Constipation and Foreign Body Ingestion Managed Conservatively: A Rare Case Report
An 18‐Year‐Old Congenitally Deaf and Mute Male With Prolonged Constipation and Foreign Body Ingestion Managed Conservatively: A Rare Case Report Open
Foreign body ingestion in adults is rare and typically linked to psychiatric or cognitive disorders. We present a rare and challenging case of an 18‐year‐old congenitally deaf and mute male who presented with prolonged constipation and rec…
View article: Analyzing Financial Socialization's Impact on Investment Decisions: Mediating Role of Financial Self-Efficacy and Moderating Effect of Cognitive Financial Competence
Analyzing Financial Socialization's Impact on Investment Decisions: Mediating Role of Financial Self-Efficacy and Moderating Effect of Cognitive Financial Competence Open
The present quantitative study enhances research knowledge regarding financial socialisation effects on financial decision-making quality by determining financial self-efficacy as a mediating factor, together with cognitive financial compe…
View article: Frailty Indices in Patients Undergoing Functional Neurosurgical Procedures: A Systematic Review
Frailty Indices in Patients Undergoing Functional Neurosurgical Procedures: A Systematic Review Open
Introduction: Functional neurosurgery covers a wide array of neurological disorders with an equally vast array of treatment modalities, including neuromodulation, decompressive, and ablative therapies for disparate pathologies such as pain…
View article: Fig ( <i>Ficus carica</i> ) as a source of bioactive compounds: nutritional, medicinal, and food industry perspectives
Fig ( <i>Ficus carica</i> ) as a source of bioactive compounds: nutritional, medicinal, and food industry perspectives Open
Fig (Ficus carica), one of the primary fruit used by human, has significant cultural importance and has been traditionally used for the treatment of various disorders. This review provides a detailed description of the multiple aspects of …
View article: Phyllanthus emblica: Its Health Benefits and Phytochemistry; A Detailed Review
Phyllanthus emblica: Its Health Benefits and Phytochemistry; A Detailed Review Open
Phyllanthus emblica L. (Indian gooseberry or Amla) is a well-known medicinal plant with high therapeutic and nutritional value. The plant is rich in tannins, flavonoids, alkaloids, phenolic acids, and ascorbic acid, which are responsible f…
View article: Phytochemical profiling of Withania somnifera and its effect on thermal stability of soybean oil
Phytochemical profiling of Withania somnifera and its effect on thermal stability of soybean oil Open
The current study aimed to measure antioxidant potential of Withania somnifera and its ability to protect quality of crude soybean oil at 170 °C for different time intervals. GC–MS analysis of plant powder was conducted. Ethanol, methanol,…
View article: Upadacitinib for difficult‐to‐treat paediatric Crohn's disease
Upadacitinib for difficult‐to‐treat paediatric Crohn's disease Open
Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the …
View article: Prevalence and Association of No-Reflow with The Total Ischemic Time in Patients Undergoing Primary Angioplasty
Prevalence and Association of No-Reflow with The Total Ischemic Time in Patients Undergoing Primary Angioplasty Open
The no-reflow phenomenon is harmful; hence, early diagnosis of its prevalence and predictors is crucial. Few said the time between the first symptom and PCI was a risk factor. After 6 hours of STEMI, myocardial necrosis causes capillary be…
View article: Correlation of Triglycerides to Glucose Index With the SYNTAX Score in Patients of Acute Coronary Syndrome
Correlation of Triglycerides to Glucose Index With the SYNTAX Score in Patients of Acute Coronary Syndrome Open
Objective: To determine the severity of triglycerides to glucose index and its correlation with the SYNTAX score in patients presenting with ACS. Methodology: An analytical type of cross-sectional study was done in the Department of Cardio…
View article: Comparison of Outcome between Limberg Flap and Karydakis Flap in Pilonidal Sinus Disease
Comparison of Outcome between Limberg Flap and Karydakis Flap in Pilonidal Sinus Disease Open
There was controversy regarding the treatment options for pilonidal sinus disease (PSD). Even though a number of techniques were used, such as Karydakis flap, Limberg flap, Bascom cleft lip treatment, and marsupialization, the most effecti…
View article: Echocardiographic evaluation of myocardial dysfunction in term neonates with perinatal asphyxia
Echocardiographic evaluation of myocardial dysfunction in term neonates with perinatal asphyxia Open
Background & Objective: One third of the neonatal deaths worldwide are attributed to perinatal asphyxia. We aimed to determine the prevalence and determinants of cardiac dysfunction, through echocardiographic evaluation, in term neonates w…
View article: AB076. Underutilization of epilepsy surgery in Pakistan: 10-year experience from the only comprehensive epilepsy center in the country
AB076. Underutilization of epilepsy surgery in Pakistan: 10-year experience from the only comprehensive epilepsy center in the country Open
The clinical outcomes of ES performed at our center are consistent with evidence. However, the small volume highlights the underutilization of this extremely important service. More studies are needed to identify the factors responsible fo…
View article: The need for economic evaluations for neuro-oncology in low- and middleincome: the Pakistan perspective
The need for economic evaluations for neuro-oncology in low- and middleincome: the Pakistan perspective Open
The incidence and prevalence of brain tumours havesteadily increased within low- and middle-incomecountries, similar to patterns seen in high-incomecountries. In addition to the epidemiological landscape ofbrain tumours in Pakistan, it is …
View article: Frequency and risk factors of delirium in the pediatric intensive care unit of a tertiary care hospital: A prospective observational study
Frequency and risk factors of delirium in the pediatric intensive care unit of a tertiary care hospital: A prospective observational study Open
Background: Critical illness is one of the most common causes of delirium in children which can be associated with increased morbidity and mortality. Delirium continues to be an overlooked aspect of the management of critically ill childre…
View article: Quantifying anticancer drug toxicity on white blood cell count in cancer patients: A mathematical and computational approach
Quantifying anticancer drug toxicity on white blood cell count in cancer patients: A mathematical and computational approach Open
Objectives: White blood cells (WBCs) are immune cells that fight infections and cancers. However, many cancers and their treatment with chemotherapy negatively affect the WBCs count. For oncologists and physicians, it is important to know …