Ki Hwan Moon
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View article: Assessment of the Risk of Microplastics on Gill and Gut Health and Subsequent Pathogen Susceptibility in the Goldfish Model
Assessment of the Risk of Microplastics on Gill and Gut Health and Subsequent Pathogen Susceptibility in the Goldfish Model Open
Microplastics are pervasive pollutants in aquatic ecosystems, yet their effects on fish tissues remain insufficiently characterized. Our study investigates the impact of polystyrene microplastics (0.5 and 2 μm) on the gill and intestinal t…
View article: Diversity and Bioactivities of Ulleung Island-Derived Marine Actinomycetes
Diversity and Bioactivities of Ulleung Island-Derived Marine Actinomycetes Open
Actinomycetes are key producers of bioactive secondary metabolites. In this study, sediment samples were collected using a grab sampler from the coast of Ulleung Island and inoculated on various agar media by stamping to isolate Actinomyce…
View article: Exploration of New Drug Candidate Derived from Antioxidants of Korean Native Halophytes: Control of Acinetobacter baumannii with Antipathogenic Activity
Exploration of New Drug Candidate Derived from Antioxidants of Korean Native Halophytes: Control of Acinetobacter baumannii with Antipathogenic Activity Open
The rise of antibiotic-resistant bacteria poses a significant challenge to the treatment of bacterial infections, necessitating the development of novel antibiotics or strategies to preserve the efficacy of existing ones. This study invest…
View article: Effect of polystyrene nanoplastics exposure on gene expression and pathogenesis of zoonotic pathogen, Edwardsiella piscicida
Effect of polystyrene nanoplastics exposure on gene expression and pathogenesis of zoonotic pathogen, Edwardsiella piscicida Open
A surge in the number of anthropogenic pollutants has been caused by increasing industrial activities. Nanoplastics are spotlighted as a new aquatic pollutant that are a threat to microbes and larger organisms. Our previous study showed th…
View article: Effects of Antibiotic Residues on Fish Gut Microbiome Dysbiosis and Mucosal Barrier-Related Pathogen Susceptibility in Zebrafish Experimental Model
Effects of Antibiotic Residues on Fish Gut Microbiome Dysbiosis and Mucosal Barrier-Related Pathogen Susceptibility in Zebrafish Experimental Model Open
The symbiotic community of microorganisms in the gut plays an important role in the health of the host. While many previous studies have been performed on the interactions between the gut microbiome and the host in mammals, studies in fish…
View article: The Impact of Chronic Antibiotics Exposure on the Gut Microbiome Dysbiosis and Mucosal Barrier-Related Pathogen Susceptibility in Zebrafish Model
The Impact of Chronic Antibiotics Exposure on the Gut Microbiome Dysbiosis and Mucosal Barrier-Related Pathogen Susceptibility in Zebrafish Model Open
The symbiotic community of microorganisms in the gut plays an important role in the health of the host. While many previous studies have been performed on the interaction between the gut microbiome and the host in mammals, studies in fish …
View article: Characterization of <i>Pseudomonas</i> sp. NIBR-H-19, an Antimicrobial Secondary Metabolite Producer Isolated from the Gut of Korean Native Sea Roach, <i>Ligia exotica</i>
Characterization of <i>Pseudomonas</i> sp. NIBR-H-19, an Antimicrobial Secondary Metabolite Producer Isolated from the Gut of Korean Native Sea Roach, <i>Ligia exotica</i> Open
The need to discover new types of antimicrobial agents has grown since the emergence of antibiotic-resistant pathogens that threaten human health. The world's oceans, comprising complex niches of biodiversity, are a promising environment f…
View article: Dynamics of the Gut Microbiome and Transcriptome in Korea Native Ricefish (Oryzias latipes) during Chronic Antibiotic Exposure
Dynamics of the Gut Microbiome and Transcriptome in Korea Native Ricefish (Oryzias latipes) during Chronic Antibiotic Exposure Open
Antibiotics have been widely used to inhibit microbial growth and to control bacterial infection; however, they can trigger an imbalance in the gut flora of the host and dysregulate the host gene regulatory system when discharged into the …
View article: Dynamics of Gut Microbiome and Transcriptome in Korea Native Ricefish (Oryzias latipes) during Chronic Antibiotics Exposure
Dynamics of Gut Microbiome and Transcriptome in Korea Native Ricefish (Oryzias latipes) during Chronic Antibiotics Exposure Open
Antibiotics have been used in various fields such as livestock farm and fish farm as well as hospital in order to treat diseases caused by bacteria. However, the antibiotics that are not completely decomposed, but remains as residue and di…
View article: Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins
Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins Open
Despite the wealth of knowledge on the diversity of biochemical activities carried out by T6SS effectors, comparably little is known about the various strategies that bacteria employ to prevent susceptibility to T6SS-dependent bacterial ki…
View article: Formylglycine-generating enzyme-like proteins constitute a novel family of widespread type VI secretion system immunity proteins
Formylglycine-generating enzyme-like proteins constitute a novel family of widespread type VI secretion system immunity proteins Open
Competition is a critical aspect of bacterial life, as it enables niche establishment and facilitates the acquisition of essential nutrients. Warfare between Gram-negative bacteria is largely mediated by the type VI secretion system (T6SS)…
View article: In vitro Edwardsiella piscicida CK108 Transcriptome Profiles with Subinhibitory Concentrations of Phenol and Formalin Reveal New Insights into Bacterial Pathogenesis Mechanisms
In vitro Edwardsiella piscicida CK108 Transcriptome Profiles with Subinhibitory Concentrations of Phenol and Formalin Reveal New Insights into Bacterial Pathogenesis Mechanisms Open
Phenol and formalin are major water pollutants that are frequently discharged into the aquatic milieu. These chemicals can affect broad domains of life, including microorganisms. Aquatic pollutants, unlike terrestrial pollutants, are easil…
View article: Draft Genome Sequence of a Fish Pathogen, <i>Edwardsiella piscicida</i> Isolate CK41
Draft Genome Sequence of a Fish Pathogen, <i>Edwardsiella piscicida</i> Isolate CK41 Open
Edwardsiella piscicida CK41 is a fish-pathogenic Gram-negative bacterium isolated from diseased flounder in the Republic of Korea. Here, we report the genome sequence of E. piscicida CK41, comprising one chromosome of 3.76 Mbp and one plas…
View article: Anthocyanins: Natural Sources and Traditional Therapeutic Uses
Anthocyanins: Natural Sources and Traditional Therapeutic Uses Open
Anthocyanins are water-soluble naturally occurring pigments that are therapeutically beneficial and that have gained considerable interests by researchers in the field of phytopharmaceuticals and pharmacology. The evidence based scientific…
View article: The Sterilization Effect of Methylene Blue, Formalin, and Iodine on Egg and Adult Stage of Marine Medaka, Oryzias dancena
The Sterilization Effect of Methylene Blue, Formalin, and Iodine on Egg and Adult Stage of Marine Medaka, Oryzias dancena Open
The sterilization effects of methylene blue (MB), formalin, and iodine on the egg of marine medaka, Oryzias dancena, were investigated for disinfecting naididae worm, Chaetogaster diastrophus through sterilization. To determi…
View article: Structural insights into flagellar stator–rotor interactions
Structural insights into flagellar stator–rotor interactions Open
The bacterial flagellar motor is a molecular machine that can rotate the flagellar filament at high speed. The rotation is generated by the stator–rotor interaction, coupled with an ion flux through the torque-generating stator. Here we em…
View article: Author response: Structural insights into flagellar stator–rotor interactions
Author response: Structural insights into flagellar stator–rotor interactions Open
View article: Multidrug-resistant plasmids repress chromosomally encoded T6SS to enable their dissemination
Multidrug-resistant plasmids repress chromosomally encoded T6SS to enable their dissemination Open
Acinetobacter baumannii ( Ab ) is a nosocomial pathogen with one of the highest rates of multidrug resistance (MDR). This is partially due to transmissible plasmids. Many Ab strains harbor a constitutively active type VI secretion system (…
View article: A tetratricopeptide repeat domain protein has profound effects on assembly of periplasmic flagella, morphology and motility of the lyme disease spirochete <i>Borrelia burgdorferi</i>
A tetratricopeptide repeat domain protein has profound effects on assembly of periplasmic flagella, morphology and motility of the lyme disease spirochete <i>Borrelia burgdorferi</i> Open
Summary Spirochetes possess a unique periplasmic flagellar motor component called the collar. However, little is known about the composition or function of the flagellar collar proteins. To identify a collar protein, we have inactivated al…
View article: Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression
Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression Open
Acinetobacter baumannii is emerging as a multidrug-resistant nosocomial pathogen of increasing threat to human health worldwide. Pili are important bacterial virulence factors, playing a role in attachment to host cells and biofilm formati…
View article: Borrelia burgdorferi CheY2 Is Dispensable for Chemotaxis or Motility but Crucial for the Infectious Life Cycle of the Spirochete
Borrelia burgdorferi CheY2 Is Dispensable for Chemotaxis or Motility but Crucial for the Infectious Life Cycle of the Spirochete Open
The requirements for bacterial chemotaxis and motility range from dispensable to crucial for host colonization. Even though more than 50% of all sequenced prokaryotic genomes possess at least one chemotaxis signaling system, many of those …
View article: Spirochetes flagellar collar protein FlbB has astounding effects in orientation of periplasmic flagella, bacterial shape, motility, and assembly of motors in <i>Borrelia burgdorferi</i>
Spirochetes flagellar collar protein FlbB has astounding effects in orientation of periplasmic flagella, bacterial shape, motility, and assembly of motors in <i>Borrelia burgdorferi</i> Open
Summary Borrelia burgdorferi , the causative agent of Lyme disease, is a highly motile spirochete, and motility, which is provided by its periplasmic flagella, is critical for every part of the spirochete's enzootic life cycle. Unlike exte…
View article: The<i>Borrelia burgdorferi</i>CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle
The<i>Borrelia burgdorferi</i>CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle Open
Borrelia burgdorferi possesses a sophisticated and complex chemotaxis system, but how the organism utilizes this system in its natural enzootic life cycle is poorly understood. Of the three CheY chemotaxis response regulators in B. burgdor…
View article: Borrelia burgdorferi CheD Promotes Various Functions in Chemotaxis and the Pathogenic Life Cycle of the Spirochete
Borrelia burgdorferi CheD Promotes Various Functions in Chemotaxis and the Pathogenic Life Cycle of the Spirochete Open
Borrelia burgdorferi possesses a sophisticated chemotaxis signaling system; however, the roles of the majority of the chemotaxis proteins in the infectious life cycle have not yet been demonstrated. Specifically, the role of CheD during ho…