Kieran Nicholson
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View article: CCDC 2143223: Experimental Crystal Structure Determination
CCDC 2143223: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2143224: Experimental Crystal Structure Determination
CCDC 2143224: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2143222: Experimental Crystal Structure Determination
CCDC 2143222: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: <i>B</i>–N/<i>B</i>–H Transborylation: borane-catalysed nitrile hydroboration
<i>B</i>–N/<i>B</i>–H Transborylation: borane-catalysed nitrile hydroboration Open
The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis. Herein, a borane-catalysed hydroboration of nitriles to give …
View article: Boron-Catalyzed, Diastereo- and Enantioselective Allylation of Ketones with Allenes
Boron-Catalyzed, Diastereo- and Enantioselective Allylation of Ketones with Allenes Open
The diastereo- and enantioselective allylation of ketones remains a synthetic challenge, with transition metal catalysis offering the most applied methods. Here, a boron-catalyzed allylation of ketones with allenes is presented. Excellent …
View article: Diastereoselective, Catalytic Access to Cross‐Aldol Products Directly from Esters and Lactones
Diastereoselective, Catalytic Access to Cross‐Aldol Products Directly from Esters and Lactones Open
High oxidation‐state carbonyl coupling partners including esters and lactones were reacted with enones to give aldol‐type products directly using two‐fold organoborane catalysis. This new retrosynthetic disconnection to aldol‐type products…
View article: Diastereoselective, Catalytic Access to Cross‐Aldol Products Directly from Esters and Lactones
Diastereoselective, Catalytic Access to Cross‐Aldol Products Directly from Esters and Lactones Open
High oxidation‐state carbonyl coupling partners including esters and lactones were reacted with enones to give aldol‐type products directly using two‐fold organoborane catalysis. This new retrosynthetic disconnection to aldol‐type products…
View article: CCDC 2077934: Experimental Crystal Structure Determination
CCDC 2077934: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: A boron–nitrogen transborylation enabled, borane-catalysed reductive cyanation of enones
A boron–nitrogen transborylation enabled, borane-catalysed reductive cyanation of enones Open
The borane-catalysed hydrocyanation of enones has been developed and applied across a series of substrates including those being functional groups susceptible to reduction.
View article: A Boron-Oxygen Transborylation Strategy for the Asymmetric Reduction of Ketones
A Boron-Oxygen Transborylation Strategy for the Asymmetric Reduction of Ketones Open
The asymmetric reduction of ketones with pinacolborane (HBpin) has been catalysed by an enantioenriched borane catalyst, formed in situ from 9-borabicyclo[3.3.1]nonane (H- B -9-BBN) and β-pinene. While previously only used stoichiometrical…
View article: A Boron-Oxygen Transborylation Strategy for the Asymmetric Reduction of Ketones
A Boron-Oxygen Transborylation Strategy for the Asymmetric Reduction of Ketones Open
The asymmetric reduction of ketones with pinacolborane (HBpin) has been catalysed by an enantioenriched borane catalyst, formed in situ from 9-borabicyclo[3.3.1]nonane (H-B-9-BBN) and β-pinene. While previously only used stoi…
View article: A Boron–Boron Double Transborylation Strategy for the Synthesis of <i>gem</i> -Diborylalkanes
A Boron–Boron Double Transborylation Strategy for the Synthesis of <i>gem</i> -Diborylalkanes Open
Olefin hydroboration reactions provide efficient access to synthetically versatile and easily handled organoboronic esters. In this study, we demonstrate that the commercially available organoborane reagent 9-borabicyclo[3.3.1]nonane (H-B-…
View article: A Boron-Boron Double Transborylation Strategy for the Synthesis of gem-Diborylalkanes
A Boron-Boron Double Transborylation Strategy for the Synthesis of gem-Diborylalkanes Open
9-Borabicyclo[3.3.1]nonane (H-B-9-BBN) has been used as a catalyst for the sequential double hydroboration of alkynes with pinacolborane (HBpin) to give alkyl gem-di-pinacol boronic esters. This strategy, which is effective for a wi…
View article: A Boron-Boron Double Transborylation Strategy for the Synthesis of gem-Diborylalkanes
A Boron-Boron Double Transborylation Strategy for the Synthesis of gem-Diborylalkanes Open
9-Borabicyclo[3.3.1]nonane (H- B -9-BBN) has been used as a catalyst for the sequential double hydroboration of alkynes with pinacolborane (HBpin) to give alkyl gem-di-pinacol boronic esters. This strategy, which is effective for a wide ra…